Impact of Fractional Flow Reserve Derived From Coronary Computed Tomography Angiography on Heart Team Treatment Decision-Making in Patients With Multivessel Coronary Artery Disease: Insights From the SYNTAX III REVOLUTION Trial.


Journal

Circulation. Cardiovascular interventions
ISSN: 1941-7632
Titre abrégé: Circ Cardiovasc Interv
Pays: United States
ID NLM: 101499602

Informations de publication

Date de publication:
12 2019
Historique:
entrez: 14 12 2019
pubmed: 14 12 2019
medline: 28 7 2020
Statut: ppublish

Résumé

Fractional flow reserve (FFR) is a reliable tool for the functional assessment of coronary stenoses. FFR computed tomography (CT) derived (FFR The trial was an international, multicenter study randomizing 2 heart teams to make a treatment decision between percutaneous coronary interventions and coronary artery bypass grafting using either coronary computed tomography angiography or conventional angiography. The heart teams received the FFR Overall, 223 patients were included. Coronary computed tomography angiography assessment was feasible in 99% of the patients and FFR In patients with 3-vessel coronary artery disease, a noninvasive physiology assessment using FFR URL: https://www.clinicaltrials.gov. Unique identifier: NCT02813473.

Sections du résumé

BACKGROUND
Fractional flow reserve (FFR) is a reliable tool for the functional assessment of coronary stenoses. FFR computed tomography (CT) derived (FFR
METHODS
The trial was an international, multicenter study randomizing 2 heart teams to make a treatment decision between percutaneous coronary interventions and coronary artery bypass grafting using either coronary computed tomography angiography or conventional angiography. The heart teams received the FFR
RESULTS
Overall, 223 patients were included. Coronary computed tomography angiography assessment was feasible in 99% of the patients and FFR
CONCLUSIONS
In patients with 3-vessel coronary artery disease, a noninvasive physiology assessment using FFR
CLINICAL TRIAL REGISTRATION
URL: https://www.clinicaltrials.gov. Unique identifier: NCT02813473.

Identifiants

pubmed: 31833413
doi: 10.1161/CIRCINTERVENTIONS.118.007607
doi:

Banques de données

ClinicalTrials.gov
['NCT02813473']

Types de publication

Journal Article Multicenter Study Randomized Controlled Trial Research Support, Non-U.S. Gov't

Langues

eng

Sous-ensembles de citation

IM

Pagination

e007607

Commentaires et corrections

Type : CommentIn

Auteurs

Daniele Andreini (D)

Centro Cardiologico Monzino, IRCCS, Milan, Italy (D.A., S.M., S.d.M., M.R., G.B., M.G., C.F., P.O., L.C., A.L.B.).
Department of Clinical Sciences and Community Health, Cardiovascular Section (D.A.), University of Milan, Italy.

Rodrigo Modolo (R)

Department of Cardiology, Amsterdam University Medical Center, the Netherlands (R.M., Y.K.).
Department of Internal Medicine, Cardiology Division, Hospital de Clinicas, University of Campinas, SP, Brazil (R.M.).

Yuki Katagiri (Y)

Department of Cardiology, Amsterdam University Medical Center, the Netherlands (R.M., Y.K.).

Saima Mushtaq (S)

Centro Cardiologico Monzino, IRCCS, Milan, Italy (D.A., S.M., S.d.M., M.R., G.B., M.G., C.F., P.O., L.C., A.L.B.).

Jeroen Sonck (J)

Cardiovascular Center Aalst, OLV Hospital, Belgium (J.S., C.C.).

Carlos Collet (C)

Cardiovascular Center Aalst, OLV Hospital, Belgium (J.S., C.C.).

Stefano De Martini (S)

Centro Cardiologico Monzino, IRCCS, Milan, Italy (D.A., S.M., S.d.M., M.R., G.B., M.G., C.F., P.O., L.C., A.L.B.).

Maurizio Roberto (M)

Centro Cardiologico Monzino, IRCCS, Milan, Italy (D.A., S.M., S.d.M., M.R., G.B., M.G., C.F., P.O., L.C., A.L.B.).

Kaoru Tanaka (K)

Universitair Ziekenhuis Brussel, Vrije Universiteit Brussel, Belgium (K.T., J.C., D.S.).

Yosuke Miyazaki (Y)

Thoraxcenter, Erasmus MC, the Netherlands (Y.M., Y.O.).

Jens Czapla (J)

Universitair Ziekenhuis Brussel, Vrije Universiteit Brussel, Belgium (K.T., J.C., D.S.).

Danny Schoors (D)

Universitair Ziekenhuis Brussel, Vrije Universiteit Brussel, Belgium (K.T., J.C., D.S.).

Andre Plass (A)

University of Zurich, Switzerland (A.P., F.M., P.K.).

Francesco Maisano (F)

University of Zurich, Switzerland (A.P., F.M., P.K.).

Philipp Kaufmann (P)

University of Zurich, Switzerland (A.P., F.M., P.K.).

Xavier Orry (X)

CHRU Nancy and Universite de Lorraine, Nancy, France (X.O., P.-A.M., T.F.).

Pierre-Adrien Metzdorf (PA)

CHRU Nancy and Universite de Lorraine, Nancy, France (X.O., P.-A.M., T.F.).

Thierry Folliguet (T)

CHRU Nancy and Universite de Lorraine, Nancy, France (X.O., P.-A.M., T.F.).

Gloria Färber (G)

Jena University Hospital, Friedrich Schiller University of Jena, Germany (G.F., I.D.).

Ioannis Diamantis (I)

Jena University Hospital, Friedrich Schiller University of Jena, Germany (G.F., I.D.).

Marc Schönweiß (M)

Heinrich Braun Klinikum, Zwickau, Germany (M.S.).

Giorgia Bonalumi (G)

Centro Cardiologico Monzino, IRCCS, Milan, Italy (D.A., S.M., S.d.M., M.R., G.B., M.G., C.F., P.O., L.C., A.L.B.).

Marco Guglielmo (M)

Centro Cardiologico Monzino, IRCCS, Milan, Italy (D.A., S.M., S.d.M., M.R., G.B., M.G., C.F., P.O., L.C., A.L.B.).

Cristina Ferrari (C)

Centro Cardiologico Monzino, IRCCS, Milan, Italy (D.A., S.M., S.d.M., M.R., G.B., M.G., C.F., P.O., L.C., A.L.B.).

Paolo Olivares (P)

Centro Cardiologico Monzino, IRCCS, Milan, Italy (D.A., S.M., S.d.M., M.R., G.B., M.G., C.F., P.O., L.C., A.L.B.).

Laura Cavallotti (L)

Centro Cardiologico Monzino, IRCCS, Milan, Italy (D.A., S.M., S.d.M., M.R., G.B., M.G., C.F., P.O., L.C., A.L.B.).

Ingrid Leal (I)

Cardialysis BV, Rotterdam, the Netherlands (I.L., W.L.).

Wietze Lindeboom (W)

Cardialysis BV, Rotterdam, the Netherlands (I.L., W.L.).

Yoshinobu Onuma (Y)

Thoraxcenter, Erasmus MC, the Netherlands (Y.M., Y.O.).

Patrick W Serruys (PW)

Department of Cardiology, Royal Brompton and Harefield Hospitals, Imperial College London, United Kingdom (P.W.S.).

Antonio L Bartorelli (AL)

Centro Cardiologico Monzino, IRCCS, Milan, Italy (D.A., S.M., S.d.M., M.R., G.B., M.G., C.F., P.O., L.C., A.L.B.).
Department of Biomedical and Clinical Sciences "Luigi Sacco" (A.L.B.), University of Milan, Italy.

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