Levels of glutamatergic neurometabolites in patients with severe treatment-resistant schizophrenia: a proton magnetic resonance spectroscopy study.


Journal

Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology
ISSN: 1740-634X
Titre abrégé: Neuropsychopharmacology
Pays: England
ID NLM: 8904907

Informations de publication

Date de publication:
03 2020
Historique:
received: 07 08 2019
accepted: 07 12 2019
revised: 08 11 2019
pubmed: 17 12 2019
medline: 29 12 2020
entrez: 17 12 2019
Statut: ppublish

Résumé

Approximately 30% of patients with schizophrenia do not respond to antipsychotics and are thus considered to have treatment-resistant schizophrenia (TRS). To date, only four studies have examined glutamatergic neurometabolite levels using proton magnetic resonance spectroscopy (

Identifiants

pubmed: 31842203
doi: 10.1038/s41386-019-0589-z
pii: 10.1038/s41386-019-0589-z
pmc: PMC7021829
doi:

Substances chimiques

Antipsychotic Agents 0
Glutamic Acid 3KX376GY7L

Types de publication

Journal Article Research Support, Non-U.S. Gov't

Langues

eng

Sous-ensembles de citation

IM

Pagination

632-640

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Auteurs

Ryosuke Tarumi (R)

Department of Neuropsychiatry, School of Medicine, Keio University, Tokyo, Japan.
Department of Psychiatry, Komagino Hospital, Hachioji, Japan.

Sakiko Tsugawa (S)

Department of Neuropsychiatry, School of Medicine, Keio University, Tokyo, Japan.

Yoshihiro Noda (Y)

Department of Neuropsychiatry, School of Medicine, Keio University, Tokyo, Japan.

Eric Plitman (E)

Cerebral Imaging Centre, Douglas Mental Health University Institute, McGill University, Montreal, QC, Canada.
Department of Psychiatry, McGill University, Montreal, QC, Canada.

Shiori Honda (S)

Graduate School of Media and Governance, Keio University, Tokyo, Japan.

Karin Matsushita (K)

Faculty of Environment and Information Studies, Keio University, Tokyo, Japan.

Sofia Chavez (S)

Campbell Institute Research Program, Centre for Addiction and Mental Health, Toronto, ON, Canada.

Kyosuke Sawada (K)

Department of Neuropsychiatry, School of Medicine, Keio University, Tokyo, Japan.

Masataka Wada (M)

Department of Neuropsychiatry, School of Medicine, Keio University, Tokyo, Japan.

Mie Matsui (M)

Department of Clinical Cognitive Neuroscience, Institute of Liberal Arts and Science, Kanazawa University, Kanazawa, Japan.

Shinya Fujii (S)

Faculty of Environment and Information Studies, Keio University, Tokyo, Japan.

Takahiro Miyazaki (T)

Department of Neuropsychiatry, School of Medicine, Keio University, Tokyo, Japan.

M Mallar Chakravarty (MM)

Cerebral Imaging Centre, Douglas Mental Health University Institute, McGill University, Montreal, QC, Canada.
Department of Psychiatry, McGill University, Montreal, QC, Canada.
Department of Biomedical Engineering, McGill University, Montreal, QC, Canada.

Hiroyuki Uchida (H)

Department of Neuropsychiatry, School of Medicine, Keio University, Tokyo, Japan.
Campbell Institute Research Program, Centre for Addiction and Mental Health, Toronto, ON, Canada.

Gary Remington (G)

Campbell Institute Research Program, Centre for Addiction and Mental Health, Toronto, ON, Canada.
Department of Psychiatry, University of Toronto, Toronto, ON, Canada.

Ariel Graff-Guerrero (A)

Campbell Institute Research Program, Centre for Addiction and Mental Health, Toronto, ON, Canada.
Department of Psychiatry, University of Toronto, Toronto, ON, Canada.

Masaru Mimura (M)

Department of Neuropsychiatry, School of Medicine, Keio University, Tokyo, Japan.

Shinichiro Nakajima (S)

Department of Neuropsychiatry, School of Medicine, Keio University, Tokyo, Japan. shinichiro_nakajima@hotmail.com.
Campbell Institute Research Program, Centre for Addiction and Mental Health, Toronto, ON, Canada. shinichiro_nakajima@hotmail.com.

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Classifications MeSH