Reasons for low cervical cancer survival in new accession European Union countries: a EUROCARE-5 study.
Cervical cancer
Europe
Morphology
Population-based study
Stage at diagnosis
Survival
Journal
Archives of gynecology and obstetrics
ISSN: 1432-0711
Titre abrégé: Arch Gynecol Obstet
Pays: Germany
ID NLM: 8710213
Informations de publication
Date de publication:
02 2020
02 2020
Historique:
received:
11
08
2019
accepted:
07
12
2019
pubmed:
20
12
2019
medline:
4
8
2020
entrez:
20
12
2019
Statut:
ppublish
Résumé
With better access to early diagnosis and appropriate treatment, cervical cancer (CC) burden decreased in several European countries. In Eastern European (EE) countries, which accessed European Union in 2004, CC survival was worse than in the rest of Europe. The present study investigates CC survival differences across five European regions, considering stage at diagnosis (local, regional and metastatic), morphology (mainly squamous versus glandular tumours) and patients' age. We analysed 101,714 CC women diagnosed in 2000-2007 and followed-up to December 2008. Age-standardised 5-year relative survival (RS) and the excess risks of cancer death in the 5 years after diagnosis were computed. EE women were older and less commonly diagnosed with glandular tumours. Proportions of local stage cancers were similar across Europe, while morphology- and stage-specific RS (especially for non-metastatic disease) were lower in Eastern Europe. Adjusting for age and morphology, excess risk of local stage CC death for EE patients remained higher than that for other European women. Stage, age and morphology alone do not explain worse survival in Eastern Europe: less effective care may play a role, probably partly due to fewer or inadequate resources being allocated to health care in this area, compared to the rest of Europe.
Identifiants
pubmed: 31853712
doi: 10.1007/s00404-019-05412-5
pii: 10.1007/s00404-019-05412-5
doi:
Types de publication
Journal Article
Research Support, Non-U.S. Gov't
Langues
eng
Sous-ensembles de citation
IM
Pagination
591-602Subventions
Organisme : Compagnia di San Paolo
ID : na
Pays : International
Organisme : Fondazione Cariplo (IT)
ID : na
Pays : International
Organisme : European Commission
ID : 20102202
Pays : International
Organisme : European Action Against Cancer
ID : na
Pays : International
Organisme : Ministero della Salute
ID : 1529710
Pays : International
Investigateurs
M Hackl
(M)
P Ihle
(P)
E Van Eycken
(E)
K Henau
(K)
Z Valerianova
(Z)
N Dimitrova
(N)
M Sekerija
(M)
P Cukelj
(P)
L Dušek
(L)
M Zvolský
(M)
M Mägi
(M)
T Aareleid
(T)
N Malila
(N)
K Seppä
(K)
M Velten
(M)
A V Guizard
(AV)
J Faivre
(J)
A S Woronoff
(AS)
B Tretarre
(B)
N Bossard
(N)
Z Uhry
(Z)
M Colonna
(M)
F Molinié
(F)
A Cowppli-Bony
(A)
S Bara
(S)
B Lapôtre-Ledoux
(B)
P Grosclaude
(P)
R Stabenow
(R)
S Luttmann
(S)
A Eberle
(A)
H Brenner
(H)
A Nennecke
(A)
J Engel
(J)
G Schubert-Fritschle
(G)
J Heidrich
(J)
B Holleczek
(B)
A Katalinic
(A)
H Birgisson
(H)
L Tryggvadóttir
(L)
K Clough-Gorr
(K)
G Mazzoleni
(G)
A Bulatko
(A)
C Buzzoni
(C)
A Sutera Sardo
(A)
P Mancuso
(P)
S Ferretti
(S)
A Barchielli
(A)
A Caldarella
(A)
G Gatta
(G)
M Sant
(M)
C Amati
(C)
P Baili
(P)
F Berrino
(F)
S Bonfarnuzzo
(S)
L Botta
(L)
R Capocaccia
(R)
R Foschi
(R)
C Margutti
(C)
E Meneghini
(E)
P Minicozzi
(P)
A Trama
(A)
D Serraino
(D)
L Dal Maso
(L)
R De Angelis
(R)
C Di Benedetto
(C)
M Caldora
(M)
S Francisci
(S)
F Galati
(F)
S Mallone
(S)
D Pierannunzio
(D)
M Tallon
(M)
S Rossi
(S)
M Santaquilani
(M)
A Tavilla
(A)
F Pannozzo
(F)
S Busco
(S)
R A Filiberti
(RA)
E Marani
(E)
P Ricci
(P)
G Spagnoli
(G)
C Cirilli
(C)
M Fusco
(M)
M F Vitale
(MF)
M Usala
(M)
F Vitale
(F)
W Mazzucco
(W)
M Michiara
(M)
R Zanetti
(R)
S Rosso
(S)
R Tumino
(R)
L Mangone
(L)
E Di Felice
(E)
A G Russo
(AG)
A Andreano
(A)
F Falcini
(F)
A L Caiazzo
(AL)
R Cesaraccio
(R)
S Piffer
(S)
A Madeddu
(A)
F Tisano
(F)
A C Fanetti
(AC)
I Cometti
(I)
P Candela
(P)
T Scuderi
(T)
F Stracci
(F)
F Bianconi
(F)
G Tagliabue
(G)
P Contiero
(P)
M Rugge
(M)
M Zorzi
(M)
S Pildava
(S)
G Smailyte
(G)
M Azzopardi
(M)
N Calleja
(N)
T B Johannesen
(TB)
J Rachtan
(J)
S Góźdź
(S)
P Macek
(P)
J Błaszczyk
(J)
M Bębenek
(M)
M Bielska-Lasota
(M)
G Forjaz de Lacerda
(G)
M J Bento
(MJ)
L Antunes
(L)
A Miranda
(A)
A Mayer-da-Silva
(A)
C Safaei Diba
(C)
V Zadnik
(V)
M Primic-Zakelj
(M)
A Lopez de Munain
(A)
L Gil
(L)
J M Díaz García
(JM)
A I Marcos-Navarro
(AI)
R Marcos-Gragera
(R)
M Puigdemont
(M)
M J Sanchez
(MJ)
D Y L Chang
(DYL)
M D Chirlaque
(MD)
E Ardanaz
(E)
M Guevara
(M)
J Galceran
(J)
M Carulla
(M)
M Lambe
(M)
S Khan
(S)
K Staehelin
(K)
C Bouchardy
(C)
E Fournier
(E)
S M Mousavi
(SM)
S M Ess
(SM)
M Lorez
(M)
M Mousavi
(M)
C Herrmann
(C)
A Bordoni
(A)
A Spitale
(A)
I Konzelmann
(I)
O Visser
(O)
M Aarts
(M)
R Otter
(R)
M Coleman
(M)
C Allemani
(C)
B Rachet
(B)
J Rashbass
(J)
J Broggio
(J)
J Verne
(J)
A Gavin
(A)
D Donnelly
(D)
D Morrison
(D)
R Black
(R)
D W Huws
(DW)
R Thomas
(R)
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