Genetic Protection Modifications: Moving Beyond the Binary Distinction Between Therapy and Enhancement for Human Genome Editing.


Journal

The CRISPR journal
ISSN: 2573-1602
Titre abrégé: CRISPR J
Pays: United States
ID NLM: 101738191

Informations de publication

Date de publication:
12 2019
Historique:
entrez: 21 12 2019
pubmed: 21 12 2019
medline: 21 7 2020
Statut: ppublish

Résumé

The current debate and policy surrounding the use of genome editing in humans typically relies on a binary distinction between therapy and human enhancement. Here, we argue that this dichotomy fails to take into account perhaps the most significant potential uses of CRISPR-Cas9 genome editing in humans. We argue that genetic treatment of sporadic Alzheimer's disease, breast and ovarian cancer predisposing

Identifiants

pubmed: 31860350
doi: 10.1089/crispr.2019.0024
doi:

Substances chimiques

RNA, Guide 0

Types de publication

Journal Article Research Support, Non-U.S. Gov't

Langues

eng

Sous-ensembles de citation

IM

Pagination

362-369

Auteurs

Rasmus Bjerregaard Mikkelsen (RB)

Department of Food and Resource Economics, Aarhus University, Aarhus, Denmark.

Henriette Reventlow S Frederiksen (HRS)

Department of Veterinary and Animal Sciences, University of Copenhagen, Frederiksberg, Denmark.

Mickey Gjerris (M)

Department of Food and Resource Economics, Aarhus University, Aarhus, Denmark.

Bjørn Holst (B)

Department of Bioneer A/S, Hørsholm, Denmark.

Poul Hyttel (P)

Department of Veterinary and Animal Sciences, University of Copenhagen, Frederiksberg, Denmark.

Yonglun Luo (Y)

Department of Lars Bolund Institute of Regenerative Medicine, BGI-Shenzhen, Shenzhen, PR China.
Department of Department of Biomedicine, Aarhus University, Aarhus, Denmark.

Kristine Freude (K)

Department of Veterinary and Animal Sciences, University of Copenhagen, Frederiksberg, Denmark.

Peter Sandøe (P)

Department of Food and Resource Economics, Aarhus University, Aarhus, Denmark.
Department of Veterinary and Animal Sciences, University of Copenhagen, Frederiksberg, Denmark.

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Classifications MeSH