Local delivery of corticosteroids in clinical ophthalmology: A review.

Adrenal Cortex Hormones Glucocorticoids / therapeutic use Humans Macular Edema Ophthalmology
Fluocinolone acetonide corticosteroid dexamethasone prednisolone acetate triamcinolone acetonide

Journal

Clinical & experimental ophthalmology
ISSN: 1442-9071
Titre abrégé: Clin Exp Ophthalmol
Pays: Australia
ID NLM: 100896531

Informations de publication

Date de publication:
04 2020
Historique:
received: 23 07 2019
revised: 21 11 2019
accepted: 09 12 2019
pubmed: 21 12 2019
medline: 26 8 2021
entrez: 21 12 2019
Statut: ppublish

Résumé

Locally administered steroids have a long history in ophthalmology for the treatment of inflammatory conditions. Anterior segment conditions tend to be treated with topical steroids whilst posterior segment conditions generally require periocular, intravitreal or systemic administration for penetration. Over recent decades, the clinical applications of periocular steroid delivery have expanded to a wide range of conditions including macular oedema from retino-vascular conditions. Formulations have been developed with the aim to provide practical, targeted, longer-term and more efficacious therapy whilst minimizing side effects. Herein, we provide a comprehensive overview of the types of periocular steroid delivery, their clinical applications in ophthalmology and their side effects.

Identifiants

DOI: 10.1111/ceo.13702 PMID: 31860766 PMC: PMC7187156
pubmed: 31860766
doi: 10.1111/ceo.13702
pmc: PMC7187156
doi:

Substances chimiques

Adrenal Cortex Hormones 0
Glucocorticoids 0

Types de publication

Journal Article Review

Langues

eng

Sous-ensembles de citation

IM

Pagination

366-401

Informations de copyright

© 2019 The Authors. Clinical & Experimental Ophthalmology published by John Wiley & Sons Australia, Ltd on behalf of Royal Australian and New Zealand College of Ophthalmologists.

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Auteurs

Adrian T Fung (AT)

Westmead Clinical School, Discipline of Clinical Ophthalmology and Eye Health, University of Sydney, Sydney, New South Wales, Australia.
Department of Ophthalmology, Faculty of Medicine and Health Sciences, Macquarie University, Sydney, New South Wales, Australia.
Save Sight Institute, Central Clinical School, Discipline of Clinical Ophthalmology and Eye Health, University of Sydney, Sydney, New South Wales, Australia.
ORCID: 0000-0002-1117-3893

Tuan Tran (T)

Save Sight Institute, Central Clinical School, Discipline of Clinical Ophthalmology and Eye Health, University of Sydney, Sydney, New South Wales, Australia.
ORCID: 0000-0002-0853-2226

Lyndell L Lim (LL)

Royal Victorian Eye and Ear Hospital, Melbourne, Victoria, Australia.
Centre for Eye Research Australia, Melbourne, Victoria, Australia.
University of Melbourne, Melbourne, Victoria, Australia.

Chameen Samarawickrama (C)

Westmead Clinical School, Discipline of Clinical Ophthalmology and Eye Health, University of Sydney, Sydney, New South Wales, Australia.
Save Sight Institute, Central Clinical School, Discipline of Clinical Ophthalmology and Eye Health, University of Sydney, Sydney, New South Wales, Australia.
Liverpool Clinical School, Faculty of Medicine, University of New South Wales, Sydney, New South Wales, Australia.

Jennifer Arnold (J)

Marsden Eye Specialists, Sydney, New South Wales, Australia.

Mark Gillies (M)

Save Sight Institute, Central Clinical School, Discipline of Clinical Ophthalmology and Eye Health, University of Sydney, Sydney, New South Wales, Australia.

Caroline Catt (C)

Save Sight Institute, Central Clinical School, Discipline of Clinical Ophthalmology and Eye Health, University of Sydney, Sydney, New South Wales, Australia.
Children's Hospital Westmead, Westmead, New South Wales, Australia.

Logan Mitchell (L)

University of Otago, Dunedin, New Zealand.

Andrew Symons (A)

Royal Melbourne Hospital, Melbourne, Victoria, Australia.

Robert Buttery (R)

Melbourne Retina Associates, Melbourne, Victoria, Australia.

Lisa Cottee (L)

Eye Doctors Mona Vale, Sydney, New South Wales, Australia.

Krishna Tumuluri (K)

Westmead Clinical School, Discipline of Clinical Ophthalmology and Eye Health, University of Sydney, Sydney, New South Wales, Australia.
Department of Ophthalmology, Faculty of Medicine and Health Sciences, Macquarie University, Sydney, New South Wales, Australia.
Save Sight Institute, Central Clinical School, Discipline of Clinical Ophthalmology and Eye Health, University of Sydney, Sydney, New South Wales, Australia.

Paul Beaumont (P)

Eye Doctors Mona Vale, Sydney, New South Wales, Australia.

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Classifications MeSH

questionsmedicales.fr › Hormones corticosurrénaliennes › Local delivery of corticosteroids in clinical...
questionsmedicales.fr › Actions chimiques et utilisations › Actions pharmacologiques › Effets physiologiques des médicaments › Hormones, substituts d'hormones et antagonistes d'hormones › Hormones › Glucocorticoïdes › Local delivery of corticosteroids in clinical...
questionsmedicales.fr › Eucaryotes › Animaux › Chordés › Vertébrés › Mammifères › Eutheria › Primates › Haplorhini › Catarrhini › Hominidae › Humains › Local delivery of corticosteroids in clinical...
questionsmedicales.fr › Maladies de l'oeil › Rétinopathies › Dégénérescence de la rétine › Dégénérescence maculaire › Oedème maculaire › Local delivery of corticosteroids in clinical...
questionsmedicales.fr › Professions de santé › Médecine › Spécialités chirurgicales › Ophtalmologie › Local delivery of corticosteroids in clinical...