Quantitative classification of chromatin dynamics reveals regulators of intestinal stem cell differentiation.

Animals Cell Differentiation / genetics Chromatin / metabolism Chromatin Assembly and Disassembly DNA Methylation Gene Expression Profiling Gene Regulatory Networks Genes, Reporter Intestines / cytology Male Mice Mice, Inbred C57BL Organ Culture Techniques SOX9 Transcription Factor / genetics Stem Cells / metabolism
5hmC Chromatin Differentiation Id3 Intestinal stem cell

Journal

Development (Cambridge, England)
ISSN: 1477-9129
Titre abrégé: Development
Pays: England
ID NLM: 8701744

Informations de publication

Date de publication:
03 01 2020
Historique:
received: 25 06 2019
accepted: 27 11 2019
pubmed: 22 12 2019
medline: 11 7 2020
entrez: 22 12 2019
Statut: epublish

Résumé

Intestinal stem cell (ISC) plasticity is thought to be regulated by broadly permissive chromatin shared between ISCs and their progeny. Here, we have used a Sox9

Identifiants

DOI: 10.1242/dev.181966 PMID: 31862843 PMC: PMC6983707
pubmed: 31862843
pii: dev.181966
doi: 10.1242/dev.181966
pmc: PMC6983707
pii:
doi:

Substances chimiques

Chromatin 0
SOX9 Transcription Factor 0
Sox9 protein, mouse 0

Types de publication

Journal Article Research Support, N.I.H., Extramural Research Support, Non-U.S. Gov't

Langues

eng

Sous-ensembles de citation

IM

Subventions

Organisme : NIDDK NIH HHS
ID : R03 DK122111
Pays : United States
Organisme : NIDDK NIH HHS
ID : R01 DK091427
Pays : United States
Organisme : NIDDK NIH HHS
ID : P30 DK034987
Pays : United States
Organisme : NCI NIH HHS
ID : P30 CA016086
Pays : United States
Organisme : NIDDK NIH HHS
ID : K01 DK111709
Pays : United States

Informations de copyright

© 2020. Published by The Company of Biologists Ltd.

Déclaration de conflit d'intérêts

Competing interestsThe authors declare no competing or financial interests.

Références

Gastroenterology. 2018 Nov;155(5):1508-1523.e10
pubmed: 30055169
Genes Dev. 2011 Apr 1;25(7):679-84
pubmed: 21460036
J Biol Chem. 2016 Feb 19;291(8):4256-65
pubmed: 26703470
Genome Biol. 2013 May 28;14(5):R50
pubmed: 23714178
Cell Rep. 2018 Aug 28;24(9):2312-2328.e7
pubmed: 30157426
Cell. 2019 Feb 7;176(4):897-912.e20
pubmed: 30686579
Gastroenterology. 2009 Dec;137(6):2052-62
pubmed: 19737569
Nucleic Acids Res. 2001 May 1;29(9):e45
pubmed: 11328886
Cell Stem Cell. 2011 Sep 2;9(3):219-32
pubmed: 21885018
Physiol Rev. 2010 Oct;90(4):1337-81
pubmed: 20959618
Mol Syst Biol. 2018 Jun 26;14(6):e8227
pubmed: 29945941
J Biol Chem. 2013 Jan 18;288(3):1929-38
pubmed: 23192339
Nutrients. 2018 Dec 22;11(1):null
pubmed: 30583500
Nature. 2014 Feb 27;506(7489):511-5
pubmed: 24413398
Genome Res. 2015 Nov;25(11):1757-70
pubmed: 26314830
Nat Genet. 2019 May;51(5):777-785
pubmed: 30988513
Science. 2014 Aug 22;345(6199):943-9
pubmed: 25103404
Nature. 2015 Feb 19;518(7539):317-30
pubmed: 25693563
EMBO J. 2012 Jun 12;31(14):3079-91
pubmed: 22692129
Nat Cell Biol. 2015 Mar;17(3):340-9
pubmed: 25664616
Cancer Cell. 2012 Jun 12;21(6):777-92
pubmed: 22698403
Nucleic Acids Res. 2017 Jun 2;45(10):5770-5784
pubmed: 28334816
Nature. 2017 May 11;545(7653):238-242
pubmed: 28467820
EMBO J. 2017 Apr 3;36(7):869-885
pubmed: 28077488
Nat Methods. 2017 Oct;14(10):975-978
pubmed: 28825706
Genes Dev. 2016 Nov 1;30(21):2433-2442
pubmed: 27856615
Cell Stem Cell. 2017 Jul 6;21(1):65-77.e5
pubmed: 28648363
Mol Cell. 2016 Aug 18;63(4):711-719
pubmed: 27477909
Am J Physiol Gastrointest Liver Physiol. 2010 May;298(5):G590-600
pubmed: 20185687
Nature. 2007 Oct 25;449(7165):1003-7
pubmed: 17934449
Proc Natl Acad Sci U S A. 2014 Aug 12;111(32):E3306-15
pubmed: 25071199
Nature. 2013 Mar 7;495(7439):65-9
pubmed: 23446353
EMBO J. 2013 Mar 6;32(5):645-55
pubmed: 23353889
Am J Physiol Gastrointest Liver Physiol. 2009 May;296(5):G1108-18
pubmed: 19228882
Gastroenterology. 2015 Nov;149(6):1553-1563.e10
pubmed: 26170137
Stem Cell Reports. 2014 Aug 12;3(2):234-41
pubmed: 25254337
Nature. 2015 Feb 19;518(7539):413-6
pubmed: 25487152
Cell. 1990 Apr 6;61(1):49-59
pubmed: 2156629
Methods Mol Biol. 2018;1799:397-417
pubmed: 29956167
Nat Methods. 2017 Oct;14(10):959-962
pubmed: 28846090
Nature. 2017 Nov 16;551(7680):333-339
pubmed: 29144463
Nat Methods. 2017 Apr;14(4):417-419
pubmed: 28263959
Cell Rep. 2016 Aug 23;16(8):2053-2060
pubmed: 27524622
Cell Stem Cell. 2016 Feb 4;18(2):203-13
pubmed: 26831517
J Am Soc Nephrol. 2008 Apr;19(4):667-71
pubmed: 18287559
Nature. 2015 Feb 19;518(7539):331-6
pubmed: 25693564

Auteurs

Jesse R Raab (JR)

Department of Genetics, University of North Carolina at Chapel Hill, NC 27599, USA.
Lineberger Comprehensive Cancer Center, University of North Carolina at Chapel Hill, NC 27599, USA.
ORCID: 0000-0001-6387-8994

Deepthi Y Tulasi (DY)

Department of Genetics, University of North Carolina at Chapel Hill, NC 27599, USA.

Kortney E Wager (KE)

Department of Genetics, University of North Carolina at Chapel Hill, NC 27599, USA.

Jeremy M Morowitz (JM)

Department of Genetics, University of North Carolina at Chapel Hill, NC 27599, USA.

Scott T Magness (ST)

Center for Gastrointestinal Biology and Disease, University of North Carolina at Chapel Hill, NC 27599, USA.
Department of Cell Biology and Physiology, University of North Carolina at Chapel Hill, NC 27599, USA.
Joint Department of Biomedical Engineering, University of North Carolina at Chapel Hill/North Carolina State University, NC 27599, USA.

Adam D Gracz (AD)

Department of Genetics, University of North Carolina at Chapel Hill, NC 27599, USA agracz@med.unc.edu.
Center for Gastrointestinal Biology and Disease, University of North Carolina at Chapel Hill, NC 27599, USA.
ORCID: 0000-0003-1298-568X

Articles similaires

Smoking Cessation and Incident Cardiovascular Disease.

Jun Hwan Cho, Seung Yong Shin, Hoseob Kim et al.
1.00
Humans Male Smoking Cessation Cardiovascular Diseases Female

Evaluation of Low-Value Services Across Major Medicare Advantage Insurers and Traditional Medicare.

Ciara Duggan, Adam L Beckman, Ishani Ganguli et al.
1.00
Humans United States Aged Cross-Sectional Studies Medicare Part C

Effectiveness of Virtual Yoga for Chronic Low Back Pain: A Randomized Clinical Trial.

Hallie Tankha, Devyn Gaskins, Amanda Shallcross et al.
1.00
Humans Yoga Low Back Pain Female Male

Meal Timing and Anthropometric and Metabolic Outcomes: A Systematic Review and Meta-Analysis.

Hiu Yee Liu, Ashley A Eso, Nathan Cook et al.
1.00
Humans Meals Time Factors Female Adult

Classifications MeSH

questionsmedicales.fr › Eucaryotes › Animaux › Quantitative classification of chromatin...
questionsmedicales.fr › Phénomènes physiologiques cellulaires › Différenciation cellulaire › Quantitative classification of chromatin...
questionsmedicales.fr › Phénomènes génétiques › Structures génétiques › Structures de chromosome › Chromatine › Quantitative classification of chromatin...
questionsmedicales.fr › Phénomènes génétiques › Régulation de l'expression des gènes › Assemblage et désassemblage de la chromatine › Quantitative classification of chromatin...
questionsmedicales.fr › Phénomènes génétiques › Méthylation de l'ADN › Quantitative classification of chromatin...
questionsmedicales.fr › Techniques d'investigation › Techniques génétiques › Analyse de profil d'expression de gènes › Quantitative classification of chromatin...
questionsmedicales.fr › Phénomènes génétiques › Structures génétiques › Séquences d'acides nucléiques régulatrices › Réseaux de régulation génique › Quantitative classification of chromatin...
questionsmedicales.fr › Phénomènes génétiques › Structures génétiques › Génome › Composants de génome › Gènes › Gènes rapporteurs › Quantitative classification of chromatin...
questionsmedicales.fr › Système digestif › Tube digestif › Intestins › Quantitative classification of chromatin...
questionsmedicales.fr › Eucaryotes › Animaux › Chordés › Vertébrés › Mammifères › Eutheria › Rodentia › Muridae › Murinae › Souris › Quantitative classification of chromatin...
questionsmedicales.fr › Eucaryotes › Animaux › Chordés › Vertébrés › Mammifères › Eutheria › Rodentia › Muridae › Murinae › Souris › Lignées consanguines de souris › Souris de lignée C57BL › Quantitative classification of chromatin...
questionsmedicales.fr › Techniques d'investigation › Techniques in vitro › Techniques de culture › Techniques de culture d'organes › Quantitative classification of chromatin...
questionsmedicales.fr › Acides aminés, peptides et protéines › Protéines › Facteurs de transcription › Facteurs de transcription SOX › Facteurs de transcription SOX-E › Facteur de transcription SOX-9 › Quantitative classification of chromatin...
questionsmedicales.fr › Cellules › Cellules souches › Quantitative classification of chromatin...