Bipolarins A-H, eight new ophiobolin-type sesterterpenes with antimicrobial activity from fungus Bipolaris sp. TJ403-B1.

Anti-Infective Agents / chemistry Ascomycota / drug effects China Crystallography, X-Ray Magnetic Resonance Spectroscopy Molecular Structure Sesterterpenes / chemistry Triticum / microbiology
Antimicrobial activity Bipolaris sp. Ophiobolins Sesterterpenes

Journal

Chinese journal of natural medicines
ISSN: 1875-5364
Titre abrégé: Chin J Nat Med
Pays: China
ID NLM: 101504416

Informations de publication

Date de publication:
Dec 2019
Historique:
received: 10 10 2019
entrez: 29 12 2019
pubmed: 29 12 2019
medline: 14 5 2020
Statut: ppublish

Résumé

Bipolarins A-H (1-8), eight new tetracyclic ophiobolin-type sesterterpenes featuring a rare oxaspiro[4.4]nonane moiety, were isolated from cultures of fungus Bipolaris sp. TJ403-B1. Their structures and absolute configurations were elucidated by comprehensive spectroscopic analyses, single-crystal X-ray diffraction experiments, electronic circular dichroism and

Identifiants

DOI: 10.1016/S1875-5364(19)30116-5 PMID: 31882049
pubmed: 31882049
pii: S1875-5364(19)30116-5
doi: 10.1016/S1875-5364(19)30116-5
pii:
doi:

Substances chimiques

Anti-Infective Agents 0
Sesterterpenes 0
ophiobolins 0

Types de publication

Journal Article

Langues

eng

Sous-ensembles de citation

IM

Pagination

935-944

Informations de copyright

Copyright © 2019 China Pharmaceutical University. Published by Elsevier B.V. All rights reserved.

Auteurs

Meng-Ting Liu (MT)

Hubei Key Laboratory of Natural Medicinal Chemistry and Resource Evaluation, School of Pharmacy, Tongji Medical College, Huazhong University of Science and Technology, Wuhan 430030, China.

Yan He (Y)

Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan 430030, China.

Ling Shen (L)

Hubei Key Laboratory of Natural Medicinal Chemistry and Resource Evaluation, School of Pharmacy, Tongji Medical College, Huazhong University of Science and Technology, Wuhan 430030, China.

Zheng-Xi Hu (ZX)

Hubei Key Laboratory of Natural Medicinal Chemistry and Resource Evaluation, School of Pharmacy, Tongji Medical College, Huazhong University of Science and Technology, Wuhan 430030, China. Electronic address: hzx616@126.com.

Yong-Hui Zhang (YH)

Hubei Key Laboratory of Natural Medicinal Chemistry and Resource Evaluation, School of Pharmacy, Tongji Medical College, Huazhong University of Science and Technology, Wuhan 430030, China. Electronic address: zhangyh@mails.tjmu.edu.cn.

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Classifications MeSH

questionsmedicales.fr › Actions chimiques et utilisations › Actions pharmacologiques › Utilisations thérapeutiques › Anti-infectieux › Bipolarins A-H, eight new ophiobolin-type...
questionsmedicales.fr › Eucaryotes › Champignons › Ascomycota › Bipolarins A-H, eight new ophiobolin-type...
questionsmedicales.fr › Régions géographiques › Asie › Extrême-Orient › Chine › Bipolarins A-H, eight new ophiobolin-type...
questionsmedicales.fr › Techniques d'investigation › Techniques de chimie analytique › Cristallographie aux rayons X › Bipolarins A-H, eight new ophiobolin-type...
questionsmedicales.fr › Techniques d'investigation › Techniques de chimie analytique › Analyse spectrale › Spectroscopie par résonance magnétique › Bipolarins A-H, eight new ophiobolin-type...
questionsmedicales.fr › Phénomènes chimiques › Structure moléculaire › Bipolarins A-H, eight new ophiobolin-type...
questionsmedicales.fr › Composés chimiques organiques › Hydrocarbures › Terpènes › Sesterterpènes › Bipolarins A-H, eight new ophiobolin-type...
questionsmedicales.fr › Eucaryotes › Viridiplantae › Streptophyta › Embryophyta › Tracheobionta › Magnoliopsida › Poaceae › Triticum › Bipolarins A-H, eight new ophiobolin-type...