Small-scale bioreactor supports high density HEK293 cell perfusion culture for the production of recombinant Erythropoietin.
Chinese Hamster Ovary (CHO) cells
Erythropoietin
High cell density culture
Human embryonic kidney 239 (HEK293) cells
Perfusion process
Small-scale bioreactor
Journal
Journal of biotechnology
ISSN: 1873-4863
Titre abrégé: J Biotechnol
Pays: Netherlands
ID NLM: 8411927
Informations de publication
Date de publication:
10 Feb 2020
10 Feb 2020
Historique:
received:
15
01
2019
revised:
11
12
2019
accepted:
26
12
2019
pubmed:
1
1
2020
medline:
15
9
2020
entrez:
1
1
2020
Statut:
ppublish
Résumé
Process intensification in mammalian cell culture-based recombinant protein production has been achieved by high cell density perfusion exceeding 10
Identifiants
pubmed: 31891733
pii: S0168-1656(19)30953-8
doi: 10.1016/j.jbiotec.2019.12.017
pii:
doi:
Substances chimiques
Recombinant Proteins
0
Erythropoietin
11096-26-7
Oxygen
S88TT14065
Types de publication
Journal Article
Langues
eng
Sous-ensembles de citation
IM
Pagination
44-52Informations de copyright
Copyright © 2019 Elsevier B.V. All rights reserved.
Déclaration de conflit d'intérêts
Declaration of Competing Interest The authors declare that they have no known competing financial interests or personal relationships that could have appeared to influence the work reported in this paper.