Accueil
Johan Rockberg
Johan Rockberg
Affiliations
KTH Royal Institute of Technology, Department of Protein Science, 10691 Stockholm, Sweden.
Publications (22)
Systematic use of synthetic 5'-UTR RNA structures to tune protein translation improves yield and quality of complex proteins in mammalian cell factories.
Nucleic acids research
Avec:
Peter Eisenhut
,
Aman Mebrahtu
,
Mona Moradi Barzadd
,
Niklas Thalén
,
Gerald Klanert
,
Marcus Weinguny
,
Anna Sandegren
,
Chao Su
,
Diane Hatton
,
Nicole Borth
,
Johan Rockberg
Enhanced metabolism and negative regulation of ER stress support higher erythropoietin production in HEK293 cells.
Cell reports
Avec:
Rasool Saghaleyni
,
Magdalena Malm
,
Noah Moruzzi
,
Jan Zrimec
,
Ronia Razavi
,
Num Wistbacka
,
Hannes Thorell
,
Anton Pintar
,
Andreas Hober
,
Fredrik Edfors
,
Veronique Chotteau
,
Per-Olof Berggren
,
Luigi Grassi
,
Aleksej Zelezniak
,
Thomas Svensson
,
Diane Hatton
,
Jens Nielsen
,
Jonathan L Robinson
,
Johan Rockberg
An easy-to-use high-throughput selection system for the discovery of recombinant protein binders from alternative scaffold libraries.
Protein engineering, design & selection : PEDS
Avec:
Marit Möller
,
Malin Jönsson
,
Magnus Lundqvist
,
Blenda Hedin
,
Louise Larsson
,
Emma Larsson
,
Johan Rockberg
,
Mathias Uhlén
,
Sarah Lindbo
,
Hanna Tegel
,
Sophia Hober
High throughput generation of a resource of the human secretome in mammalian cells.
New biotechnology
Avec:
Hanna Tegel
,
Melanie Dannemeyer
,
Sara Kanje
,
Åsa Sivertsson
,
Anna Berling
,
Anne-Sophie Svensson
,
Andreas Hober
,
Henric Enstedt
,
Anna-Luisa Volk
,
Magnus Lundqvist
,
Mona Moradi
,
Delaram Afshari
,
Siri Ekblad
,
LanLan Xu
,
Malin Westin
,
Faranak Bidad
,
Lovisa Holmberg Schiavone
,
Rick Davies
,
Lorenz M Mayr
,
Sinead Knight
,
Sven O Göpel
,
Björn G Voldborg
,
Fredrik Edfors
,
Björn Forsström
,
Kalle von Feilitzen
,
Martin Zwahlen
,
Johan Rockberg
,
Jenny Ottosson Takanen
,
Mathias Uhlén
,
Sophia Hober
Ancestral lysosomal enzymes with increased activity harbor therapeutic potential for treatment of Hunter syndrome.
iScience
Avec:
Natalie M Hendrikse
,
Anna Sandegren
,
Tommy Andersson
,
Jenny Blomqvist
,
Åsa Makower
,
Dominik Possner
,
Chao Su
,
Niklas Thalén
,
Agneta Tjernberg
,
Ulrica Westermark
,
Johan Rockberg
,
Stefan Svensson Gelius
,
Per-Olof Syrén
,
Erik Nordling
CaRA - A multi-purpose phage display library for selection of calcium-regulated affinity proteins.
New biotechnology
Avec:
Malin Jönsson
,
Julia Scheffel
,
Emma Larsson
,
Marit Möller
,
Gabriella Rossi
,
Magnus Lundqvist
,
Johan Rockberg
,
Mathias Uhlén
,
Hanna Tegel
,
Sara Kanje
,
Sophia Hober
Mammalian cell display with automated oligo design and library assembly allows for rapid residue level conformational epitope mapping.
Communications biology
Avec:
Niklas Berndt Thalén
,
Maximilian Karlander
,
Magnus Lundqvist
,
Helena Persson
,
Camilla Hofström
,
S Pauliina Turunen
,
Magdalena Godzwon
,
Anna-Luisa Volk
,
Magdalena Malm
,
Mats Ohlin
,
Johan Rockberg
The human secretome.
Science signaling
Avec:
Mathias Uhlén
,
Max J Karlsson
,
Andreas Hober
,
Anne-Sophie Svensson
,
Julia Scheffel
,
David Kotol
,
Wen Zhong
,
Abdellah Tebani
,
Linnéa Strandberg
,
Fredrik Edfors
,
Evelina Sjöstedt
,
Jan Mulder
,
Adil Mardinoglu
,
Anna Berling
,
Siri Ekblad
,
Melanie Dannemeyer
,
Sara Kanje
,
Johan Rockberg
,
Magnus Lundqvist
,
Magdalena Malm
,
Anna-Luisa Volk
,
Peter Nilsson
,
Anna Månberg
,
Tea Dodig-Crnkovic
,
Elisa Pin
,
Martin Zwahlen
,
Per Oksvold
,
Kalle von Feilitzen
,
Ragna S Häussler
,
Mun-Gwan Hong
,
Cecilia Lindskog
,
Fredrik Ponten
,
Borbala Katona
,
Jimmy Vuu
,
Emil Lindström
,
Jens Nielsen
,
Jonathan Robinson
,
Burcu Ayoglu
,
Diana Mahdessian
,
Devin Sullivan
,
Peter Thul
,
Frida Danielsson
,
Charlotte Stadler
,
Emma Lundberg
,
Göran Bergström
,
Anders Gummesson
,
Bjørn G Voldborg
,
Hanna Tegel
,
Sophia Hober
,
Björn Forsström
,
Jochen M Schwenk
,
Linn Fagerberg
,
Åsa Sivertsson
Small-scale bioreactor supports high density HEK293 cell perfusion culture for the production of recombinant Erythropoietin.
Journal of biotechnology
Avec:
Hubert Schwarz
,
Ye Zhang
,
Caijuan Zhan
,
Magdalena Malm
,
Raymond Field
,
Richard Turner
,
Christopher Sellick
,
Paul Varley
,
Johan Rockberg
,
Véronique Chotteau
SAMURAI (Solid-phase Assisted Mutagenesis by Uracil Restriction for Accurate Integration) for antibody affinity maturation and paratope mapping.
Nucleic acids research
Avec:
Francis Jingxin Hu
,
Magnus Lundqvist
,
Mathias Uhlén
,
Johan Rockberg
Tuning of CHO secretional machinery improve activity of secreted therapeutic sulfatase 150-fold.
Metabolic engineering
Avec:
Niklas Berndt Thalén
,
Mona Moradi Barzadd
,
Magnus Lundqvist
,
Johanna Rodhe
,
Monica Andersson
,
Gholamreza Bidkhori
,
Dominik Possner
,
Chao Su
,
Joakim Nilsson
,
Peter Eisenhut
,
Magdalena Malm
,
Alice Karlsson
,
Jeanette Vestin
,
Johan Forsberg
,
Erik Nordling
,
Adil Mardinoglu
,
Anna-Luisa Volk
,
Anna Sandegren
,
Johan Rockberg
Co-culture platform for tuning of cancer receptor density allows for evaluation of bispecific immune cell engagers.
New biotechnology
Avec:
Aman Mebrahtu
,
Gustav Aniander
,
Alessandro Mega
,
Mona Moradi Barzadd
,
Niklas Berndt Thalén
,
Lindvi Gudmundsdotter
,
Eva Backström Rydin
,
Anna Sandegren
,
Fredrik Y Frejd
,
Johan Rockberg
Systematic Development of Sandwich Immunoassays for the Plasma Secretome.
Proteomics
Avec:
Ragna S Häussler
,
Annika Bendes
,
MariaJesus Iglesias
,
Laura Sanchez-Rivera
,
Tea Dodig-Crnković
,
Sanna Byström
,
Claudia Fredolini
,
Elin Birgersson
,
Matilda Dale
,
Fredrik Edfors
,
Linn Fagerberg
,
Johan Rockberg
,
Hanna Tegel
,
Mathias Uhlén
,
Ulrika Qundos
,
Jochen M Schwenk
Low Shear Stress Increases Recombinant Protein Production and High Shear Stress Increases Apoptosis in Human Cells.
iScience
Avec:
Caijuan Zhan
,
Gholamreza Bidkhori
,
Hubert Schwarz
,
Magdalena Malm
,
Aman Mebrahtu
,
Ray Field
,
Christopher Sellick
,
Diane Hatton
,
Paul Varley
,
Adil Mardinoglu
,
Johan Rockberg
,
Veronique Chotteau
Evolution from adherent to suspension: systems biology of HEK293 cell line development.
Scientific reports
Avec:
Magdalena Malm
,
Rasool Saghaleyni
,
Magnus Lundqvist
,
Marco Giudici
,
Veronique Chotteau
,
Ray Field
,
Paul G Varley
,
Diane Hatton
,
Luigi Grassi
,
Thomas Svensson
,
Jens Nielsen
,
Johan Rockberg
Small Bispecific Affinity Proteins for Simultaneous Target Binding and Albumin-Associated Half-Life Extension.
Molecular pharmaceutics
Avec:
Emma von Witting
,
Sarah Lindbo
,
Magnus Lundqvist
,
Marit Möller
,
Andreas Wisniewski
,
Sara Kanje
,
Johan Rockberg
,
Hanna Tegel
,
Mikael Åstrand
,
Mathias Uhlén
,
Sophia Hober
Harnessing secretory pathway differences between HEK293 and CHO to rescue production of difficult to express proteins.
Metabolic engineering
Avec:
Magdalena Malm
,
Chih-Chung Kuo
,
Mona Moradi Barzadd
,
Aman Mebrahtu
,
Num Wistbacka
,
Ronia Razavi
,
Anna-Luisa Volk
,
Magnus Lundqvist
,
David Kotol
,
Hanna Tegel
,
Sophia Hober
,
Fredrik Edfors
,
Torbjörn Gräslund
,
Veronique Chotteau
,
Ray Field
,
Paul G Varley
,
Robert G Roth
,
Nathan E Lewis
,
Diane Hatton
,
Johan Rockberg
Chromophore pre-maturation for improved speed and sensitivity of split-GFP monitoring of protein secretion.
Scientific reports
Avec:
Magnus Lundqvist
,
Niklas Thalén
,
Anna-Luisa Volk
,
Henning Gram Hansen
,
Eric von Otter
,
Per-Åke Nygren
,
Mathias Uhlen
,
Johan Rockberg
Reactive oxygen species as an initiator of toxic innate immune responses in retort to SARS-CoV-2 in an ageing population, consider N-acetylcysteine as early therapeutic intervention.
Toxicology reports
Avec:
Aikaterini Nasi
,
Stephanie McArdle
,
Gustav Gaudernack
,
Gabriel Westman
,
Cornelis Melief
,
Johan Rockberg
,
Ramon Arens
,
Demetrios Kouretas
,
Jan Sjölin
,
Sara Mangsbo
Bispecific Antibody Molecule Inhibits Tumor Cell Proliferation More Efficiently Than the Two-Molecule Combination.
Drugs in R&D
Avec:
Anna-Luisa Volk
,
Aman Mebrahtu
,
Bong-Kook Ko
,
Magnus Lundqvist
,
Maximilian Karlander
,
Hyun-Jong Lee
,
Fredrik Y Frejd
,
Kyu-Tae Kim
,
Jong-Seo Lee
,
Johan Rockberg
Secretome screening reveals immunomodulating functions of IFNα-7, PAP and GDF-7 on regulatory T-cells.
Scientific reports
Avec:
Mei Ding
,
Rajneesh Malhotra
,
Tomas Ottosson
,
Magnus Lundqvist
,
Aman Mebrahtu
,
Johan Brengdahl
,
Ulf Gehrmann
,
Elisabeth Bäck
,
Douglas Ross-Thriepland
,
Ida Isaksson
,
Björn Magnusson
,
Kris F Sachsenmeier
,
Hanna Tegel
,
Sophia Hober
,
Mathias Uhlén
,
Lorenz M Mayr
,
Rick Davies
,
Johan Rockberg
,
Lovisa Holmberg Schiavone
Autophagy and intracellular product degradation genes identified by systems biology analysis reduce aggregation of bispecific antibody in CHO cells.
New biotechnology
Avec:
Mona Moradi Barzadd
,
Magnus Lundqvist
,
Claire Harris
,
Magdalena Malm
,
Anna-Luisa Volk
,
Niklas Thalén
,
Veronique Chotteau
,
Luigi Grassi
,
Andrew Smith
,
Marina Leal Abadi
,
Giulia Lambiase
,
Suzanne Gibson
,
Diane Hatton
,
Johan Rockberg
Réseau de co-auteurs
Magnus Lundqvist
14 collaborations
Magdalena Malm
9 collaborations
Mathias Uhlén
8 collaborations
Hanna Tegel
8 collaborations
Anna-Luisa Volk
8 collaborations
Sophia Hober
7 collaborations
Aman Mebrahtu
6 collaborations
Diane Hatton
6 collaborations
Mona Moradi Barzadd
5 collaborations
Fredrik Edfors
5 collaborations
Veronique Chotteau
5 collaborations
Niklas Thalén
4 collaborations
Anna Sandegren
4 collaborations
Sara Kanje
4 collaborations
Chao Su
3 collaborations
Andreas Hober
3 collaborations
Luigi Grassi
3 collaborations
Jens Nielsen
3 collaborations
Marit Möller
3 collaborations
Niklas Berndt Thalén
3 collaborations
Adil Mardinoglu
3 collaborations
Ray Field
3 collaborations
Peter Eisenhut
2 collaborations
Rasool Saghaleyni
2 collaborations
Ronia Razavi
2 collaborations
Num Wistbacka
2 collaborations
Thomas Svensson
2 collaborations
Malin Jönsson
2 collaborations
Emma Larsson
2 collaborations
Sarah Lindbo
2 collaborations
Melanie Dannemeyer
2 collaborations
Åsa Sivertsson
2 collaborations
Anna Berling
2 collaborations
Anne-Sophie Svensson
2 collaborations
Siri Ekblad
2 collaborations
Lovisa Holmberg Schiavone
2 collaborations
Rick Davies
2 collaborations
Lorenz M Mayr
2 collaborations
Björn Forsström
2 collaborations
Kalle von Feilitzen
2 collaborations
Martin Zwahlen
2 collaborations
Dominik Possner
2 collaborations
Erik Nordling
2 collaborations
Julia Scheffel
2 collaborations
Maximilian Karlander
2 collaborations
David Kotol
2 collaborations
Ragna S Häussler
2 collaborations
Jochen M Schwenk
2 collaborations
Linn Fagerberg
2 collaborations
Hubert Schwarz
2 collaborations
Caijuan Zhan
2 collaborations
Christopher Sellick
2 collaborations
Paul Varley
2 collaborations
Gholamreza Bidkhori
2 collaborations
Fredrik Y Frejd
2 collaborations
Paul G Varley
2 collaborations
Gerald Klanert
1 collaboration
Marcus Weinguny
1 collaboration
Nicole Borth
1 collaboration
Noah Moruzzi
1 collaboration
Jan Zrimec
1 collaboration
Hannes Thorell
1 collaboration
Anton Pintar
1 collaboration
Per-Olof Berggren
1 collaboration
Aleksej Zelezniak
1 collaboration
Jonathan L Robinson
1 collaboration
Blenda Hedin
1 collaboration
Louise Larsson
1 collaboration
Henric Enstedt
1 collaboration
Mona Moradi
1 collaboration
Delaram Afshari
1 collaboration
LanLan Xu
1 collaboration
Malin Westin
1 collaboration
Faranak Bidad
1 collaboration
Sinead Knight
1 collaboration
Sven O Göpel
1 collaboration
Björn G Voldborg
1 collaboration
Jenny Ottosson Takanen
1 collaboration
Natalie M Hendrikse
1 collaboration
Tommy Andersson
1 collaboration
Jenny Blomqvist
1 collaboration
Åsa Makower
1 collaboration
Agneta Tjernberg
1 collaboration
Ulrica Westermark
1 collaboration
Stefan Svensson Gelius
1 collaboration
Per-Olof Syrén
1 collaboration
Gabriella Rossi
1 collaboration
Helena Persson
1 collaboration
Camilla Hofström
1 collaboration
S Pauliina Turunen
1 collaboration
Magdalena Godzwon
1 collaboration
Mats Ohlin
1 collaboration
Max J Karlsson
1 collaboration
Wen Zhong
1 collaboration
Abdellah Tebani
1 collaboration
Linnéa Strandberg
1 collaboration
Evelina Sjöstedt
1 collaboration
Jan Mulder
1 collaboration
Peter Nilsson
1 collaboration
Anna Månberg
1 collaboration
Tea Dodig-Crnkovic
1 collaboration
Elisa Pin
1 collaboration
Per Oksvold
1 collaboration
Mun-Gwan Hong
1 collaboration
Cecilia Lindskog
1 collaboration
Fredrik Ponten
1 collaboration
Borbala Katona
1 collaboration
Jimmy Vuu
1 collaboration
Emil Lindström
1 collaboration
Jonathan Robinson
1 collaboration
Burcu Ayoglu
1 collaboration
Diana Mahdessian
1 collaboration
Devin Sullivan
1 collaboration
Peter Thul
1 collaboration
Frida Danielsson
1 collaboration
Charlotte Stadler
1 collaboration
Emma Lundberg
1 collaboration
Göran Bergström
1 collaboration
Anders Gummesson
1 collaboration
Bjørn G Voldborg
1 collaboration
Ye Zhang
1 collaboration
Raymond Field
1 collaboration
Richard Turner
1 collaboration
Véronique Chotteau
1 collaboration
Francis Jingxin Hu
1 collaboration
Johanna Rodhe
1 collaboration
Monica Andersson
1 collaboration
Joakim Nilsson
1 collaboration
Alice Karlsson
1 collaboration
Jeanette Vestin
1 collaboration
Johan Forsberg
1 collaboration
Gustav Aniander
1 collaboration
Alessandro Mega
1 collaboration
Lindvi Gudmundsdotter
1 collaboration
Eva Backström Rydin
1 collaboration
Annika Bendes
1 collaboration
MariaJesus Iglesias
1 collaboration
Laura Sanchez-Rivera
1 collaboration
Tea Dodig-Crnković
1 collaboration
Sanna Byström
1 collaboration
Claudia Fredolini
1 collaboration
Elin Birgersson
1 collaboration
Matilda Dale
1 collaboration
Ulrika Qundos
1 collaboration
Marco Giudici
1 collaboration
Emma von Witting
1 collaboration
Andreas Wisniewski
1 collaboration
Mikael Åstrand
1 collaboration
Chih-Chung Kuo
1 collaboration
Torbjörn Gräslund
1 collaboration
Robert G Roth
1 collaboration
Nathan E Lewis
1 collaboration
Henning Gram Hansen
1 collaboration
Eric von Otter
1 collaboration
Per-Åke Nygren
1 collaboration
Mathias Uhlen
1 collaboration
Aikaterini Nasi
1 collaboration
Stephanie McArdle
1 collaboration
Gustav Gaudernack
1 collaboration
Gabriel Westman
1 collaboration
Cornelis Melief
1 collaboration
Ramon Arens
1 collaboration
Demetrios Kouretas
1 collaboration
Jan Sjölin
1 collaboration
Sara Mangsbo
1 collaboration
Bong-Kook Ko
1 collaboration
Hyun-Jong Lee
1 collaboration
Kyu-Tae Kim
1 collaboration
Jong-Seo Lee
1 collaboration
Mei Ding
1 collaboration
Rajneesh Malhotra
1 collaboration
Tomas Ottosson
1 collaboration
Johan Brengdahl
1 collaboration
Ulf Gehrmann
1 collaboration
Elisabeth Bäck
1 collaboration
Douglas Ross-Thriepland
1 collaboration
Ida Isaksson
1 collaboration
Björn Magnusson
1 collaboration
Kris F Sachsenmeier
1 collaboration
Claire Harris
1 collaboration
Andrew Smith
1 collaboration
Marina Leal Abadi
1 collaboration
Giulia Lambiase
1 collaboration
Suzanne Gibson
1 collaboration