Small Bispecific Affinity Proteins for Simultaneous Target Binding and Albumin-Associated Half-Life Extension.

Bacterial Proteins / metabolism Half-Life Life Expectancy Protein Binding / physiology Recombinant Fusion Proteins / metabolism Serum Albumin / metabolism Streptococcus / metabolism Tumor Necrosis Factor-alpha / metabolism
ABD ADAPT albumin half-life extension next-generation sequencing phage display protein engineering

Journal

Molecular pharmaceutics
ISSN: 1543-8392
Titre abrégé: Mol Pharm
Pays: United States
ID NLM: 101197791

Informations de publication

Date de publication:
04 01 2021
Historique:
pubmed: 2 12 2020
medline: 6 10 2021
entrez: 1 12 2020
Statut: ppublish

Résumé

Albumin-binding fusion partners are frequently used as a means for the

Identifiants

DOI: 10.1021/acs.molpharmaceut.0c00975 PMID: 33259222 PMC: PMC9490751
pubmed: 33259222
doi: 10.1021/acs.molpharmaceut.0c00975
pmc: PMC9490751
doi:

Substances chimiques

Bacterial Proteins 0
IgG Fc-binding protein, Streptococcus 0
Recombinant Fusion Proteins 0
Serum Albumin 0
Tumor Necrosis Factor-alpha 0

Types de publication

Journal Article Research Support, Non-U.S. Gov't

Langues

eng

Sous-ensembles de citation

IM

Pagination

328-337

Commentaires et corrections

Type : ErratumIn

Références

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Auteurs

Emma von Witting (E)

Protein Science, School of Engineering Sciences in Chemistry, Biotechnology and Health, KTH Royal Institute of Technology, Stockholm 10691, Sweden.
ORCID: 0000-0002-4695-7858

Sarah Lindbo (S)

Protein Science, School of Engineering Sciences in Chemistry, Biotechnology and Health, KTH Royal Institute of Technology, Stockholm 10691, Sweden.

Magnus Lundqvist (M)

Protein Science, School of Engineering Sciences in Chemistry, Biotechnology and Health, KTH Royal Institute of Technology, Stockholm 10691, Sweden.

Marit Möller (M)

Protein Science, School of Engineering Sciences in Chemistry, Biotechnology and Health, KTH Royal Institute of Technology, Stockholm 10691, Sweden.

Andreas Wisniewski (A)

Protein Science, School of Engineering Sciences in Chemistry, Biotechnology and Health, KTH Royal Institute of Technology, Stockholm 10691, Sweden.

Sara Kanje (S)

Protein Science, School of Engineering Sciences in Chemistry, Biotechnology and Health, KTH Royal Institute of Technology, Stockholm 10691, Sweden.
ORCID: 0000-0002-4751-2519

Johan Rockberg (J)

Protein Science, School of Engineering Sciences in Chemistry, Biotechnology and Health, KTH Royal Institute of Technology, Stockholm 10691, Sweden.

Hanna Tegel (H)

Protein Science, School of Engineering Sciences in Chemistry, Biotechnology and Health, KTH Royal Institute of Technology, Stockholm 10691, Sweden.

Mikael Åstrand (M)

Protein Science, School of Engineering Sciences in Chemistry, Biotechnology and Health, KTH Royal Institute of Technology, Stockholm 10691, Sweden.

Mathias Uhlén (M)

Protein Science, School of Engineering Sciences in Chemistry, Biotechnology and Health, KTH Royal Institute of Technology, Stockholm 10691, Sweden.

Sophia Hober (S)

Protein Science, School of Engineering Sciences in Chemistry, Biotechnology and Health, KTH Royal Institute of Technology, Stockholm 10691, Sweden.
ORCID: 0000-0003-0605-8417

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Classifications MeSH

questionsmedicales.fr › Acides aminés, peptides et protéines › Protéines › Protéines bactériennes › Small Bispecific Affinity Proteins for...
questionsmedicales.fr › Phénomènes physiques › Temps › Période › Small Bispecific Affinity Proteins for...
questionsmedicales.fr › Environnement et santé publique › Santé publique › Méthodes épidémiologiques › Collecte de données › Registre civil › Espérance de vie › Small Bispecific Affinity Proteins for...
questionsmedicales.fr › Métabolisme › Liaison aux protéines › Small Bispecific Affinity Proteins for...
questionsmedicales.fr › Acides aminés, peptides et protéines › Protéines › Protéines recombinantes › Protéines de fusion recombinantes › Small Bispecific Affinity Proteins for...
questionsmedicales.fr › Acides aminés, peptides et protéines › Protéines › Protéines du sang › Sérumalbumine › Small Bispecific Affinity Proteins for...
questionsmedicales.fr › Bactéries › Bactéries à Gram positif › Lactobacillales › Streptococcaceae › Streptococcus › Small Bispecific Affinity Proteins for...
questionsmedicales.fr › Facteurs biologiques › Protéines et peptides de signalisation intercellulaire › Cytokines › Facteurs de nécrose tumorale › Facteur de nécrose tumorale alpha › Small Bispecific Affinity Proteins for...