The color of skin: white diseases of the skin, nails, and mucosa.


Journal

Clinics in dermatology
ISSN: 1879-1131
Titre abrégé: Clin Dermatol
Pays: United States
ID NLM: 8406412

Informations de publication

Date de publication:
Historique:
entrez: 4 1 2020
pubmed: 4 1 2020
medline: 11 6 2020
Statut: ppublish

Résumé

White diseases are a heterogenous group characterized by hypopigmentation or depigmentation. Skin and eye color are determined by the number and size of melanosomes present. Melanin is produced by melanosomes in the melanocytes present within the epidermis of the skin, uvea, and retinal pigmented epithelium (RPE). Conditions altering the number of melanocytes or concentration of melanin result in a lack of pigmentation, appearing as "white diseases" ranging from the well-known albinism and vitiligo to more esoteric white hand syndrome and Degos disease.

Identifiants

pubmed: 31896410
pii: S0738-081X(19)30129-4
doi: 10.1016/j.clindermatol.2019.07.018
pii:
doi:

Substances chimiques

Cosmetics 0
Skin Lightening Preparations 0

Types de publication

Journal Article

Langues

eng

Sous-ensembles de citation

IM

Pagination

561-579

Informations de copyright

Copyright © 2019 Elsevier Inc. All rights reserved.

Auteurs

Ashley E Brown (AE)

McGovern Medical School, University of Texas Health Science Center at Houston,Houston, Texas, USA. Electronic address: Ashley.brown@uth.tmc.edu.

Connie C Qiu (CC)

Lewis Katz School of Medicine, Temple University, Philadelphia, Pennsylvania, USA.

Brandy Drozd (B)

McGovern Medical School, University of Texas Health Science Center at Houston,Houston, Texas, USA.

Lindsay R Sklover (LR)

Lewis Katz School of Medicine, Temple University, Philadelphia, Pennsylvania, USA.

Conor M Vickers (CM)

Lewis Katz School of Medicine, Temple University, Philadelphia, Pennsylvania, USA.

Sylvia Hsu (S)

Department of Dermatology, Temple University Lewis Katz School of Medicine, Philadelphia, Pennsylvania, USA.

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Classifications MeSH