Impaired endothelium-mediated cerebrovascular reactivity promotes anxiety and respiration disorders in mice.


Journal

Proceedings of the National Academy of Sciences of the United States of America
ISSN: 1091-6490
Titre abrégé: Proc Natl Acad Sci U S A
Pays: United States
ID NLM: 7505876

Informations de publication

Date de publication:
21 01 2020
Historique:
pubmed: 4 1 2020
medline: 28 4 2020
entrez: 4 1 2020
Statut: ppublish

Résumé

Carbon dioxide (CO

Identifiants

pubmed: 31896584
pii: 1907467117
doi: 10.1073/pnas.1907467117
pmc: PMC6983400
doi:

Substances chimiques

GPR4 protein, mouse 0
Receptors, G-Protein-Coupled 0
Carbon Dioxide 142M471B3J
GTP-Binding Protein alpha Subunits, Gq-G11 EC 3.6.5.1

Types de publication

Journal Article Research Support, Non-U.S. Gov't

Langues

eng

Sous-ensembles de citation

IM

Pagination

1753-1761

Déclaration de conflit d'intérêts

The authors declare no competing interest.

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Auteurs

Jan Wenzel (J)

Institute for Experimental and Clinical Pharmacology and Toxicology, University of Lübeck, 23562 Lübeck, Germany; jan.wenzel@uni-luebeck.de markus.schwaninger@uni-luebeck.de.
DZHK (German Research Centre for Cardiovascular Research), partner site Hamburg/Lübeck/Kiel, 23562 Lübeck, Germany.

Cathrin E Hansen (CE)

Institute for Experimental and Clinical Pharmacology and Toxicology, University of Lübeck, 23562 Lübeck, Germany.

Carla Bettoni (C)

Institute of Physiology, University of Zürich, CH-8057 Zürich, Switzerland.

Miriam A Vogt (MA)

Central Institute of Mental Health, Medical Faculty of Mannheim/University of Heidelberg, 68159 Mannheim, Germany.

Beate Lembrich (B)

Institute for Experimental and Clinical Pharmacology and Toxicology, University of Lübeck, 23562 Lübeck, Germany.

Rentsenkhand Natsagdorj (R)

Institute for Experimental and Clinical Pharmacology and Toxicology, University of Lübeck, 23562 Lübeck, Germany.
DZHK (German Research Centre for Cardiovascular Research), partner site Hamburg/Lübeck/Kiel, 23562 Lübeck, Germany.

Gianna Huber (G)

Institute for Experimental and Clinical Pharmacology and Toxicology, University of Lübeck, 23562 Lübeck, Germany.

Josefine Brands (J)

Institute for Experimental and Clinical Pharmacology and Toxicology, University of Lübeck, 23562 Lübeck, Germany.
DZHK (German Research Centre for Cardiovascular Research), partner site Hamburg/Lübeck/Kiel, 23562 Lübeck, Germany.

Kjestine Schmidt (K)

DZHK (German Research Centre for Cardiovascular Research), partner site Hamburg/Lübeck/Kiel, 23562 Lübeck, Germany.
Institute of Physiology, University of Lübeck, 23562 Lübeck, Germany.

Julian C Assmann (JC)

Institute for Experimental and Clinical Pharmacology and Toxicology, University of Lübeck, 23562 Lübeck, Germany.

Ines Stölting (I)

Institute for Experimental and Clinical Pharmacology and Toxicology, University of Lübeck, 23562 Lübeck, Germany.

Kathrin Saar (K)

Cardiovascular and Metabolic Sciences, Max Delbrück Center for Molecular Medicine in the Helmholtz Association, 13125 Berlin, Germany.
DZHK (German Research Centre for Cardiovascular Research), partner site Berlin, 13125 Berlin, Germany.

Jan Sedlacik (J)

Department of Diagnostic and Interventional Neuroradiology, University Medical Center Hamburg-Eppendorf, 20251 Hamburg, Germany.

Jens Fiehler (J)

Department of Diagnostic and Interventional Neuroradiology, University Medical Center Hamburg-Eppendorf, 20251 Hamburg, Germany.

Peter Ludewig (P)

Department of Neurology, University Medical Center Hamburg-Eppendorf, 20251 Hamburg, Germany.

Michael Wegmann (M)

Priority Area Asthma and Allergy, Research Center Borstel, 23845 Borstel, Germany.

Nina Feller (N)

Institute for Experimental and Clinical Pharmacology and Toxicology, University of Lübeck, 23562 Lübeck, Germany.

Marius Richter (M)

Institute for Experimental and Clinical Pharmacology and Toxicology, University of Lübeck, 23562 Lübeck, Germany.

Helge Müller-Fielitz (H)

Institute for Experimental and Clinical Pharmacology and Toxicology, University of Lübeck, 23562 Lübeck, Germany.

Thomas Walther (T)

Institute for Experimental and Clinical Pharmacology and Toxicology, University of Lübeck, 23562 Lübeck, Germany.

Gabriele M König (GM)

Institute for Pharmaceutical Biology, University of Bonn, 53115 Bonn, Germany.

Evi Kostenis (E)

Institute for Pharmaceutical Biology, University of Bonn, 53115 Bonn, Germany.

Walter Raasch (W)

Institute for Experimental and Clinical Pharmacology and Toxicology, University of Lübeck, 23562 Lübeck, Germany.
DZHK (German Research Centre for Cardiovascular Research), partner site Hamburg/Lübeck/Kiel, 23562 Lübeck, Germany.

Norbert Hübner (N)

Cardiovascular and Metabolic Sciences, Max Delbrück Center for Molecular Medicine in the Helmholtz Association, 13125 Berlin, Germany.
DZHK (German Research Centre for Cardiovascular Research), partner site Berlin, 13125 Berlin, Germany.
Charité Universitätsmedizin Berlin, 10117 Berlin.

Peter Gass (P)

Central Institute of Mental Health, Medical Faculty of Mannheim/University of Heidelberg, 68159 Mannheim, Germany.

Stefan Offermanns (S)

Department of Pharmacology, Max Planck Institute for Heart and Lung Research, 61231 Bad Nauheim, Germany.

Cor de Wit (C)

DZHK (German Research Centre for Cardiovascular Research), partner site Hamburg/Lübeck/Kiel, 23562 Lübeck, Germany.
Institute of Physiology, University of Lübeck, 23562 Lübeck, Germany.

Carsten A Wagner (CA)

Institute of Physiology, University of Zürich, CH-8057 Zürich, Switzerland.

Markus Schwaninger (M)

Institute for Experimental and Clinical Pharmacology and Toxicology, University of Lübeck, 23562 Lübeck, Germany; jan.wenzel@uni-luebeck.de markus.schwaninger@uni-luebeck.de.
DZHK (German Research Centre for Cardiovascular Research), partner site Hamburg/Lübeck/Kiel, 23562 Lübeck, Germany.

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Classifications MeSH