Temporal lobe angiocentric glioma with oligodendroglioma-like areas: a rare association of an uncommon tumor. A case report with review of literature.
Angiocentric glioma
Hippocampal sclerosis
Temporal low-grade neuroepithelial tumor
Journal
Child's nervous system : ChNS : official journal of the International Society for Pediatric Neurosurgery
ISSN: 1433-0350
Titre abrégé: Childs Nerv Syst
Pays: Germany
ID NLM: 8503227
Informations de publication
Date de publication:
03 2020
03 2020
Historique:
received:
04
09
2018
accepted:
19
11
2019
pubmed:
4
1
2020
medline:
22
6
2021
entrez:
4
1
2020
Statut:
ppublish
Résumé
Angiocentric glioma (AG) is a relatively uncommon clinico-pathological entity that presents in childhood. Angiocentric glioma displays various histopathological features which resemble cortical ependymoma, astroblastoma, and pilomyxoid astrocytoma and schwannoma. The astrocytes in angiocentric glioma appear peculiarly elongated, bipolar in shape, and characteristically arranged around blood vessels. They resemble radial glia and tanycytes morphologically. Unlike ependymomas, AG is a diffusely infiltrating lesion and perivascular processes are often much thicker than those in classic ependymomas. AG usually present clinically as seizures, often as medically intractable epilepsy. In the indexed case, apart from unusual presentation with features of raised intra-cranial tension, an unusual histological picture of a more cellular oligodendroglioma like component was also seen. The appropriate diagnosis is critical as AG is usually slowly growing and treatable by surgical excision alone.
Sections du résumé
BACKGROUND
Angiocentric glioma (AG) is a relatively uncommon clinico-pathological entity that presents in childhood. Angiocentric glioma displays various histopathological features which resemble cortical ependymoma, astroblastoma, and pilomyxoid astrocytoma and schwannoma. The astrocytes in angiocentric glioma appear peculiarly elongated, bipolar in shape, and characteristically arranged around blood vessels. They resemble radial glia and tanycytes morphologically. Unlike ependymomas, AG is a diffusely infiltrating lesion and perivascular processes are often much thicker than those in classic ependymomas.
CASE PRESENTATION
AG usually present clinically as seizures, often as medically intractable epilepsy. In the indexed case, apart from unusual presentation with features of raised intra-cranial tension, an unusual histological picture of a more cellular oligodendroglioma like component was also seen.
CONCLUSION
The appropriate diagnosis is critical as AG is usually slowly growing and treatable by surgical excision alone.
Identifiants
pubmed: 31897632
doi: 10.1007/s00381-019-04445-0
pii: 10.1007/s00381-019-04445-0
doi:
Types de publication
Case Reports
Journal Article
Review
Langues
eng
Sous-ensembles de citation
IM
Pagination
641-646Références
Folia Neuropathol. 2016;54(1):40-9
pubmed: 27179220
J Neuropsychiatry Clin Neurosci. 2010 Winter;22(1):123.E18-20
pubmed: 20160231
J Neurooncol. 2012 Dec;110(3):375-80
pubmed: 23065092
Clin Neuropathol. 2007 Nov-Dec;26(6):311-6
pubmed: 18232599
Acta Neuropathol. 2017 Oct;134(4):671-673
pubmed: 28776091
Neurol India. 2016 Mar-Apr;64(2):340-3
pubmed: 26954821
Brain Pathol. 2010 Mar;20(2):503-6
pubmed: 20438470
J Radiol Case Rep. 2015 Jul 31;9(7):1-9
pubmed: 26629293
Brain Pathol. 2005 Oct;15(4):281-6
pubmed: 16389940
Neuropathol Appl Neurobiol. 2015 Apr;41(3):333-46
pubmed: 24861831
Folia Neuropathol. 2014;52(3):253-9
pubmed: 25310736
Acta Neuropathol. 2017 Mar;133(3):417-429
pubmed: 27812792
Neuropathology. 2012 Oct;32(5):479-91
pubmed: 22151480
Anticancer Res. 2015 Nov;35(11):6267-70
pubmed: 26504061
Am J Surg Pathol. 2007 Nov;31(11):1709-18
pubmed: 18059228
Arch Pathol Lab Med. 2011 Aug;135(8):1037-41
pubmed: 21809996
World Neurosurg. 2017 Jan;97:755.e5-755.e10
pubmed: 27756673
Nat Genet. 2016 Mar;48(3):273-82
pubmed: 26829751
Virchows Arch. 2017 Aug;471(2):257-269
pubmed: 28674742
J Neuropathol Exp Neurol. 2005 Oct;64(10):875-81
pubmed: 16215459
J Clin Neurosci. 2016 Jun;28:117-22
pubmed: 26778052
Perm J. 2013 Winter;17(1):e100-2
pubmed: 23596378
Acta Neuropathol. 2016 Jun;131(6):833-45
pubmed: 26810070
J Neurosurg Pediatr. 2009 Mar;3(3):197-202
pubmed: 19338465
Clin Imaging. 2012 Jan-Feb;36(1):61-4
pubmed: 22226445