Rising time from bed in acute phase after hospitalization predicts frailty at hospital discharge in patients with acute heart failure.
Elderly
Frailty
Heart failure
Hospitalized patient
Rising time from bed
Journal
Journal of cardiology
ISSN: 1876-4738
Titre abrégé: J Cardiol
Pays: Netherlands
ID NLM: 8804703
Informations de publication
Date de publication:
06 2020
06 2020
Historique:
received:
26
08
2019
revised:
21
11
2019
accepted:
08
12
2019
pubmed:
4
1
2020
medline:
22
5
2021
entrez:
4
1
2020
Statut:
ppublish
Résumé
The early prediction of frailty at discharge in elderly patients hospitalized with heart failure (HF) is essential for clinical management and therapeutic decision-making. This study was performed to examine whether the rising time from bed measured immediately after admission can be used as a predictor of frailty in these patients. A retrospective cohort study was performed in a population of 387 consecutive elderly patients with HF. Rising time from bed was measured within 2 days after admission when cardiac rehabilitation was started. Frailty was assessed at hospital discharge using a composite of four markers as a frailty score (range, 0-12): gait speed, handgrip strength, serum albumin, and activities of daily living status. The patients were divided into two groups based on frailty score <5 (non-frail) or ≥5 (frail). The study population had a mean age of 75 years and 63.6 % were men. The median rising time was 6.8s, and 53.5 % were classified as frail. After adjustment for various factors, rising time was independently associated with frailty (odds ratio=1.10; 95 % confidence index=1.04-1.18). The area under the receiver operating characteristics curve of rising time for frailty was 0.71, and the cut-off value for rising time to identify those at high risk of frailty was 7.1s. Rising time from bed measured within 2 days after admission was shown to be an independent predictor of frailty at hospital discharge in elderly patients hospitalized for HF.
Sections du résumé
BACKGROUND
The early prediction of frailty at discharge in elderly patients hospitalized with heart failure (HF) is essential for clinical management and therapeutic decision-making. This study was performed to examine whether the rising time from bed measured immediately after admission can be used as a predictor of frailty in these patients.
METHODS
A retrospective cohort study was performed in a population of 387 consecutive elderly patients with HF. Rising time from bed was measured within 2 days after admission when cardiac rehabilitation was started. Frailty was assessed at hospital discharge using a composite of four markers as a frailty score (range, 0-12): gait speed, handgrip strength, serum albumin, and activities of daily living status. The patients were divided into two groups based on frailty score <5 (non-frail) or ≥5 (frail).
RESULTS
The study population had a mean age of 75 years and 63.6 % were men. The median rising time was 6.8s, and 53.5 % were classified as frail. After adjustment for various factors, rising time was independently associated with frailty (odds ratio=1.10; 95 % confidence index=1.04-1.18). The area under the receiver operating characteristics curve of rising time for frailty was 0.71, and the cut-off value for rising time to identify those at high risk of frailty was 7.1s.
CONCLUSIONS
Rising time from bed measured within 2 days after admission was shown to be an independent predictor of frailty at hospital discharge in elderly patients hospitalized for HF.
Identifiants
pubmed: 31899114
pii: S0914-5087(19)30381-8
doi: 10.1016/j.jjcc.2019.12.007
pii:
doi:
Types de publication
Journal Article
Research Support, Non-U.S. Gov't
Langues
eng
Sous-ensembles de citation
IM
Pagination
587-593Informations de copyright
Copyright © 2019 Japanese College of Cardiology. Published by Elsevier Ltd. All rights reserved.