Determination of free apocarotenoids and apocarotenoid esters in human colostrum.
Apocarotenoids
Carotenoids
Human colostrum
SFE-SFC-APCI/QqQ/MS
Journal
Analytical and bioanalytical chemistry
ISSN: 1618-2650
Titre abrégé: Anal Bioanal Chem
Pays: Germany
ID NLM: 101134327
Informations de publication
Date de publication:
Feb 2020
Feb 2020
Historique:
received:
20
10
2019
accepted:
16
12
2019
revised:
12
12
2019
pubmed:
5
1
2020
medline:
3
4
2020
entrez:
5
1
2020
Statut:
ppublish
Résumé
The presence of carotenoids in human colostrum has been reported in the literature, and xanthophyll esters in human colostrum were recently detected for the first time. However, no published studies have reported whether apocarotenoids, which are metabolites derived from carotenoid enzymatic or nonenzymatic oxidative cleavage, are present in human colostrum. Therefore, the purpose of the present study was to search for the possible occurrence of apocarotenoids, including apocarotenoid esters, in human colostrum for the first time by applying an online supercritical fluid extraction-supercritical fluid chromatography-tandem mass spectrometry methodology. Recent evidence related to apocarotenoid transcriptional activity has suggested that they may have beneficial health properties superior to those of their parent carotenoids. Three different apocarotenoids, namely apo-8'-β-carotenal, apo-8'-lycopenal, and β-citraurin, were identified in intact human colostrum samples, with average concentrations of 85 nmol L
Identifiants
pubmed: 31900534
doi: 10.1007/s00216-019-02359-z
pii: 10.1007/s00216-019-02359-z
doi:
Substances chimiques
Esters
0
Carotenoids
36-88-4
Types de publication
Journal Article
Langues
eng
Sous-ensembles de citation
IM
Pagination
1335-1342Références
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