HHV-8-negative multicentric Castleman disease presenting as a crescentic immune complexes membranoproliferative glomerulonephritis.


Journal

BMJ case reports
ISSN: 1757-790X
Titre abrégé: BMJ Case Rep
Pays: England
ID NLM: 101526291

Informations de publication

Date de publication:
06 Jan 2020
Historique:
entrez: 9 1 2020
pubmed: 9 1 2020
medline: 15 8 2020
Statut: epublish

Résumé

Multicentric Castleman disease is a rare polyclonal lymphoproliferative disorder mainly associated with two renal manifestations: thrombotic microangiopathy and amyloidosis. Nevertheless, we report here a case of human herpes virus-8 negative multicentric Castleman disease with membranous proliferative glomerulonephritis and extracapillary proliferation. A patient was successfully treated with corticosteroids, anti-CD20 and cyclophosphamide therapy.

Identifiants

pubmed: 31911409
pii: 13/1/e231844
doi: 10.1136/bcr-2019-231844
pmc: PMC6954780
pii:
doi:

Substances chimiques

Adrenal Cortex Hormones 0
Antigen-Antibody Complex 0
Immunologic Factors 0
Immunosuppressive Agents 0
Rituximab 4F4X42SYQ6
Cyclophosphamide 8N3DW7272P

Types de publication

Case Reports Journal Article

Langues

eng

Sous-ensembles de citation

IM

Informations de copyright

© BMJ Publishing Group Limited 2020. Re-use permitted under CC BY-NC. No commercial re-use. See rights and permissions. Published by BMJ.

Déclaration de conflit d'intérêts

Competing interests: None declared.

Références

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Auteurs

Maria Brito Nunes (MB)

Internal Medicine, Centre Hospitalier Universitaire Vaudois, Lausanne, Switzerland lucilia.b.nunes@gmail.com.

Samuel Rotman (S)

Institute of Pathology, Centre Hospitalier Universitaire Vaudois, Lausanne, Switzerland.

Francois-Regis Duss (FR)

Internal Medicine, Centre Hospitalier Universitaire Vaudois, Lausanne, Switzerland.

Matthieu Halfon (M)

Nephrology, Centre Hospitalier Universitaire Vaudois, Lausanne, Switzerland.

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Classifications MeSH