New Approximate Statistical Significance of Gapped Alignments Based on the Greedy Extension Model.
Poisson clumping
biological sequences
local alignment
local score
sequence comparison
statistical significance
Journal
Journal of computational biology : a journal of computational molecular cell biology
ISSN: 1557-8666
Titre abrégé: J Comput Biol
Pays: United States
ID NLM: 9433358
Informations de publication
Date de publication:
09 2020
09 2020
Historique:
pubmed:
9
1
2020
medline:
8
10
2021
entrez:
9
1
2020
Statut:
ppublish
Résumé
Sequence alignment is a fundamental concept in bioinformatics to distinguish regions of similarity among various sequences. The degree of similarity has been considered as a score. There are a number of various methods to find the statistical significance of similarity in the gapped and ungapped cases. In this article, we improve the statistical significance accuracy of the local score by introducing a new approximate
Identifiants
pubmed: 31913652
doi: 10.1089/cmb.2018.0203
doi:
Types de publication
Journal Article
Langues
eng
Sous-ensembles de citation
IM