Utility of the global CDR

Aged Aphasia, Primary Progressive / diagnosis Cross-Sectional Studies Female Frontotemporal Lobar Degeneration / diagnosis Humans Male Mental Status and Dementia Tests / statistics & numerical data Middle Aged
CDR plus NACC FTLD CDR® behavior, comportment, and personality frontotemporal lobar degeneration global rating language

Journal

Alzheimer's & dementia : the journal of the Alzheimer's Association
ISSN: 1552-5279
Titre abrégé: Alzheimers Dement
Pays: United States
ID NLM: 101231978

Informations de publication

Date de publication:
01 2020
Historique:
received: 22 07 2019
revised: 20 11 2019
accepted: 03 12 2019
entrez: 9 1 2020
pubmed: 9 1 2020
medline: 31 10 2020
Statut: ppublish

Résumé

We created global rating scoring rules for the CDR The CDR plus NACC FTLD rating was applied to 970 sporadic and familial participants from the baseline visit of Advancing Research and Treatment in Frontotemporal Lobar Degeneration (ARTFL)/Longitudinal Evaluation of Familial Frontotemporal Dementia Subjects (LEFFTDS). Each of the eight domains of the CDR plus NACC FTLD was equally weighed in determining the global score. An interrater reliability study was completed for 40 participants. The CDR plus NACC FTLD showed very good interrater reliability. It was especially useful in detecting clinical features of mild non-fluent/agrammatic variant primary progressive aphasia participants. The global CDR plus NACC FTLD score could be an attractive outcome measure for clinical trials in symptomatic FTLD, and may be useful in natural history studies and clinical trials in FTLD spectrum disorders.

Identifiants

DOI: 10.1002/alz.12033 PMID: 31914218 PMC: PMC7202045
pubmed: 31914218
doi: 10.1002/alz.12033
pmc: PMC7202045
mid: NIHMS1581444
doi:

Types de publication

Journal Article Research Support, N.I.H., Extramural Research Support, Non-U.S. Gov't

Langues

eng

Sous-ensembles de citation

IM

Pagination

106-117

Subventions

Organisme : NIA NIH HHS
ID : P30 AG013854
Pays : United States
Organisme : NIA NIH HHS
ID : K24 AG045333
Pays : United States
Organisme : NIA NIH HHS
ID : U24 AG021886
Pays : United States
Organisme : NIA NIH HHS
ID : P50 AG005136
Pays : United States
Organisme : NIA NIH HHS
ID : P01 AG019724
Pays : United States
Organisme : NIA NIH HHS
ID : P01 AG066597
Pays : United States
Organisme : NIH HHS
ID : U01 AG045390
Pays : United States
Organisme : NIA NIH HHS
ID : R01 AG062268
Pays : United States
Organisme : NIA NIH HHS
ID : P30 AG062421
Pays : United States
Organisme : NIA NIH HHS
ID : P50 AG008702
Pays : United States
Organisme : NIA NIH HHS
ID : U19 AG063911
Pays : United States
Organisme : NIA NIH HHS
ID : U01 AG016976
Pays : United States
Organisme : NIMH NIH HHS
ID : R01 MH120794
Pays : United States
Organisme : NIH HHS
ID : U24 AG021886
Pays : United States
Organisme : NIA NIH HHS
ID : P30 AG066509
Pays : United States
Organisme : NIA NIH HHS
ID : P30 AG072977
Pays : United States
Organisme : NIH HHS
ID : U54 NS092089
Pays : United States

Informations de copyright

© 2020 the Alzheimer's Association.

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Auteurs

Toji Miyagawa (T)

Mayo Clinic, Rochester, Minnesota, USA.

Danielle Brushaber (D)

Mayo Clinic, Rochester, Minnesota, USA.

Jeremy Syrjanen (J)

Mayo Clinic, Rochester, Minnesota, USA.

Walter Kremers (W)

Mayo Clinic, Rochester, Minnesota, USA.

Julie Fields (J)

Mayo Clinic, Rochester, Minnesota, USA.

Leah K Forsberg (LK)

Mayo Clinic, Rochester, Minnesota, USA.

Hilary W Heuer (HW)

University of California San Francisco, San Francisco, California, USA.

David Knopman (D)

Mayo Clinic, Rochester, Minnesota, USA.

John Kornak (J)

University of California San Francisco, San Francisco, California, USA.

Adam Boxer (A)

University of California San Francisco, San Francisco, California, USA.

Howard J Rosen (HJ)

University of California San Francisco, San Francisco, California, USA.

Bradley F Boeve (BF)

Mayo Clinic, Rochester, Minnesota, USA.

Brian Appleby (B)

Case Western Reserve University, Cleveland, Ohio, USA.

Yvette Bordelon (Y)

University of California Los Angeles, Los Angeles, California, USA.

Jessica Bove (J)

University of Pennsylvania, Philadelphia, Pennsylvania, USA.

Patrick Brannelly (P)

Tau Consortium, Rainwater Charitable Foundation, Fort Worth, Texas, USA.

Christina Caso (C)

University of Washington, Seattle, Washington, USA.

Giovanni Coppola (G)

University of California Los Angeles, Los Angeles, California, USA.

Reilly Dever (R)

University of California San Francisco, San Francisco, California, USA.

Christina Dheel (C)

Mayo Clinic, Rochester, Minnesota, USA.

Bradford Dickerson (B)

Harvard University/Massachusetts General Hospital, Boston, Massachusetts, USA.

Susan Dickinson (S)

Association for Frontotemporal Degeneration, Radnor, Pennsylvania, USA.

Sophia Dominguez (S)

University of Pennsylvania, Philadelphia, Pennsylvania, USA.

Kimiko Domoto-Reilly (K)

University of Washington, Seattle, Washington, USA.

Kelley Faber (K)

National Centralized Repository for Alzheimer's Disease and Related Dementias (NCRAD), Indiana University, Indianapolis, Indiana, USA.

Jessica Ferrell (J)

University of North Carolina, Chapel Hill, North Carolina, USA.

Ann Fishman (A)

Johns Hopkins University, Baltimore, Maryland, USA.

Jamie Fong (J)

University of California San Francisco, San Francisco, California, USA.

Tatiana Foroud (T)

National Centralized Repository for Alzheimer's Disease and Related Dementias (NCRAD), Indiana University, Indianapolis, Indiana, USA.

Ralitza Gavrilova (R)

Mayo Clinic, Rochester, Minnesota, USA.

Debra Gearhart (D)

Mayo Clinic, Rochester, Minnesota, USA.

Behnaz Ghazanfari (B)

University of Toronto, Toronto, Ontario, Canada.

Nupur Ghoshal (N)

Washington University, St. Louis, Missouri, USA.

Jill S Goldman (JS)

Columbia University, New York, New York, USA.

Jonathan Graff-Radford (J)

Mayo Clinic, Rochester, Minnesota, USA.

Neill Graff-Radford (N)

Mayo Clinic, Jacksonville, Florida, USA.

Ian Grant (I)

Northwestern University, Chicago, Illinois, USA.

Murray Grossman (M)

University of Pennsylvania, Philadelphia, Pennsylvania, USA.

Dana Haley (D)

Mayo Clinic, Jacksonville, Florida, USA.

Robin Hsiung (R)

University of British Columbia, Vancouver, British Columbia, Canada.

Edward Huey (E)

Columbia University, New York, New York, USA.

David Irwin (D)

University of Pennsylvania, Philadelphia, Pennsylvania, USA.

David Jones (D)

Mayo Clinic, Rochester, Minnesota, USA.

Lynne Jones (L)

Washington University, St. Louis, Missouri, USA.

Kejal Kantarci (K)

Mayo Clinic, Rochester, Minnesota, USA.

Anna Karydas (A)

University of California San Francisco, San Francisco, California, USA.

Daniel Kaufer (D)

University of North Carolina, Chapel Hill, North Carolina, USA.

Diana Kerwin (D)

University of Texas Southwestern, Dallas, Texas, USA.

Ruth Kraft (R)

Mayo Clinic, Rochester, Minnesota, USA.

Joel Kramer (J)

University of California San Francisco, San Francisco, California, USA.

Walter Kukull (W)

National Alzheimer Coordinating Center (NACC), University of Washington, Seattle, Washington, USA.

Irene Litvan (I)

University of California San Diego, San Diego, California, USA.

Diane Lucente (D)

Harvard University/Massachusetts General Hospital, Boston, Massachusetts, USA.

Codrin Lungu (C)

National Institute of Neurological Disorders and Stroke (NINDS), Bethesda, Maryland, USA.

Ian Mackenzie (I)

University of British Columbia, Vancouver, British Columbia, Canada.

Miranda Maldonado (M)

University of California Los Angeles, Los Angeles, California, USA.

Masood Manoochehri (M)

Columbia University, New York, New York, USA.

Scott McGinnis (S)

Harvard University/Massachusetts General Hospital, Boston, Massachusetts, USA.

Emily McKinley (E)

University of Alabama, Birmingham, Alabama, USA.

Mario F Mendez (MF)

University of California Los Angeles, Los Angeles, California, USA.

Bruce Miller (B)

University of California San Francisco, San Francisco, California, USA.

Namita Multani (N)

University of Toronto, Toronto, Ontario, Canada.

Chiadi Onyike (C)

Johns Hopkins University, Baltimore, Maryland, USA.

Jaya Padmanabhan (J)

Harvard University/Massachusetts General Hospital, Boston, Massachusetts, USA.

Alexander Pantelyat (A)

Johns Hopkins University, Baltimore, Maryland, USA.

Rodney Pearlman (R)

Bluefield Project, San Francisco, California, USA.

Leonard Petrucelli (L)

Mayo Clinic, Jacksonville, Florida, USA.

Madeline Potter (M)

National Centralized Repository for Alzheimer's Disease and Related Dementias (NCRAD), Indiana University, Indianapolis, Indiana, USA.

Rosa Rademakers (R)

Mayo Clinic, Jacksonville, Florida, USA.

Eliana M Ramos (EM)

University of California Los Angeles, Los Angeles, California, USA.

Kate Rankin (K)

University of California San Francisco, San Francisco, California, USA.

Katya Rascovsky (K)

University of Pennsylvania, Philadelphia, Pennsylvania, USA.

Erik D Roberson (ED)

University of Alabama, Birmingham, Alabama, USA.

Emily Rogalski (E)

Northwestern University, Chicago, Illinois, USA.

Pheth Sengdy (P)

University of British Columbia, Vancouver, British Columbia, Canada.

Leslie Shaw (L)

University of Pennsylvania, Philadelphia, Pennsylvania, USA.

Maria C Tartaglia (MC)

National Centralized Repository for Alzheimer's Disease and Related Dementias (NCRAD), Indiana University, Indianapolis, Indiana, USA.

Nadine Tatton (N)

Association for Frontotemporal Degeneration, Radnor, Pennsylvania, USA.

Joanne Taylor (J)

University of California San Francisco, San Francisco, California, USA.

Arthur Toga (A)

Laboratory of Neuroimaging (LONI), University of Southern California, Los Angeles, California, USA.

John Q Trojanowski (JQ)

University of Pennsylvania, Philadelphia, Pennsylvania, USA.

Ping Wang (P)

University of California San Francisco, San Francisco, California, USA.

Sandra Weintraub (S)

Northwestern University, Chicago, Illinois, USA.

Bonnie Wong (B)

Harvard University/Massachusetts General Hospital, Boston, Massachusetts, USA.

Zbigniew Wszolek (Z)

Mayo Clinic, Jacksonville, Florida, USA.

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Classifications MeSH

questionsmedicales.fr › Personnes › Tranches d'âge › Adulte › Sujet âgé › Utility of the global CDR
questionsmedicales.fr › Troubles mentaux › Troubles neurocognitifs › Démence › Aphasie progressive primaire › Utility of the global CDR
questionsmedicales.fr › Environnement et santé publique › Santé publique › Méthodes épidémiologiques › Caractéristiques des études épidémiologiques › Études épidémiologiques › Études transversales › Utility of the global CDR
questionsmedicales.fr › Troubles mentaux › Troubles neurocognitifs › Démence › Dégénérescence lobaire frontotemporale › Utility of the global CDR
questionsmedicales.fr › Eucaryotes › Animaux › Chordés › Vertébrés › Mammifères › Eutheria › Primates › Haplorhini › Catarrhini › Hominidae › Humains › Utility of the global CDR
questionsmedicales.fr › Disciplines et activités comportementales › Tests psychologiques › Tests neuropsychologiques › Tests de l'état mental et de la démence › Utility of the global CDR
questionsmedicales.fr › Personnes › Tranches d'âge › Adulte › Adulte d'âge moyen › Utility of the global CDR