Functional Variation of IL-1R-Associated Kinases in the Conserved MyD88-TRAF6 Pathway during Evolution.

Animals Biological Evolution Lancelets Myeloid Differentiation Factor 88 / immunology Phylogeny Protein Serine-Threonine Kinases / immunology Signal Transduction / immunology TNF Receptor-Associated Factor 6 / immunology

Journal

Journal of immunology (Baltimore, Md. : 1950)
ISSN: 1550-6606
Titre abrégé: J Immunol
Pays: United States
ID NLM: 2985117R

Informations de publication

Date de publication:
15 02 2020
Historique:
received: 22 02 2019
accepted: 12 12 2019
pubmed: 10 1 2020
medline: 15 9 2020
entrez: 10 1 2020
Statut: ppublish

Résumé

IL-1R-associated kinases (IRAK) are important regulators in the TLR/IL-1R pathways, but their function appears inconsistent between

Identifiants

DOI: 10.4049/jimmunol.1900222 PMID: 31915260
pubmed: 31915260
pii: jimmunol.1900222
doi: 10.4049/jimmunol.1900222
doi:

Substances chimiques

Myeloid Differentiation Factor 88 0
TNF Receptor-Associated Factor 6 0
Protein Serine-Threonine Kinases EC 2.7.11.1

Types de publication

Journal Article Research Support, Non-U.S. Gov't

Langues

eng

Sous-ensembles de citation

IM

Pagination

832-843

Informations de copyright

Copyright © 2020 by The American Association of Immunologists, Inc.

Auteurs

Xinyu Yan (X)

State Key Laboratory of Biocontrol, Guangdong Key Laboratory of Pharmaceutical Functional Genes, School of Life Sciences, Sun Yat-sen University, 510275 Guangzhou, China.

Shenghui Chen (S)

State Key Laboratory of Biocontrol, Guangdong Key Laboratory of Pharmaceutical Functional Genes, School of Life Sciences, Sun Yat-sen University, 510275 Guangzhou, China.

Huiqing Huang (H)

Guangdong Food and Drug Vocational College, 510520 Guangzhou, China.

Ting Peng (T)

State Key Laboratory of Biocontrol, Guangdong Key Laboratory of Pharmaceutical Functional Genes, School of Life Sciences, Sun Yat-sen University, 510275 Guangzhou, China.

Mengjiao Lan (M)

State Key Laboratory of Biocontrol, Guangdong Key Laboratory of Pharmaceutical Functional Genes, School of Life Sciences, Sun Yat-sen University, 510275 Guangzhou, China.

Xia Yang (X)

State Key Laboratory of Biocontrol, Guangdong Key Laboratory of Pharmaceutical Functional Genes, School of Life Sciences, Sun Yat-sen University, 510275 Guangzhou, China.

Meiling Dong (M)

State Key Laboratory of Biocontrol, Guangdong Key Laboratory of Pharmaceutical Functional Genes, School of Life Sciences, Sun Yat-sen University, 510275 Guangzhou, China.

Shangwu Chen (S)

State Key Laboratory of Biocontrol, Guangdong Key Laboratory of Pharmaceutical Functional Genes, School of Life Sciences, Sun Yat-sen University, 510275 Guangzhou, China.

Anlong Xu (A)

State Key Laboratory of Biocontrol, Guangdong Key Laboratory of Pharmaceutical Functional Genes, School of Life Sciences, Sun Yat-sen University, 510275 Guangzhou, China; lssxal@mail.sysu.edu.cn hshengf2@mail.sysu.edu.cn.
School of Life Science, Beijing University of Chinese Medicine, 100029 Beijing, China; and.

Shengfeng Huang (S)

State Key Laboratory of Biocontrol, Guangdong Key Laboratory of Pharmaceutical Functional Genes, School of Life Sciences, Sun Yat-sen University, 510275 Guangzhou, China; lssxal@mail.sysu.edu.cn hshengf2@mail.sysu.edu.cn.
Laboratory for Marine Biology and Biotechnology, Qingdao National Laboratory for Marine Science and Technology, 266003 Qingdao, China.

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Classifications MeSH

questionsmedicales.fr › Eucaryotes › Animaux › Functional Variation of IL-1R-Associated...
questionsmedicales.fr › Phénomènes biologiques › Évolution biologique › Functional Variation of IL-1R-Associated...
questionsmedicales.fr › Eucaryotes › Animaux › Invertébrés › Chordés invertébrés › Cephalochordata › Lancelets › Functional Variation of IL-1R-Associated...
questionsmedicales.fr › Acides aminés, peptides et protéines › Protéines › Protéines et peptides de signalisation intracellulaire › Protéines adaptatrices de la transduction du signal › Facteur de différenciation myéloïde-88 › Functional Variation of IL-1R-Associated...
questionsmedicales.fr › Sciences de l'information › Phylogenèse › Functional Variation of IL-1R-Associated...
questionsmedicales.fr › Acides aminés, peptides et protéines › Protéines › Protéines et peptides de signalisation intracellulaire › Protein-Serine-Threonine Kinases › Functional Variation of IL-1R-Associated...
questionsmedicales.fr › Phénomènes physiologiques cellulaires › Transduction du signal › Functional Variation of IL-1R-Associated...
questionsmedicales.fr › Acides aminés, peptides et protéines › Protéines › Protéines et peptides de signalisation intracellulaire › Protéines adaptatrices de la transduction du signal › Protéines et peptides associés aux récepteurs des facteurs de nécrose tumorale › Facteur-6 associé aux récepteurs de TNF › Functional Variation of IL-1R-Associated...