How aging affects the premotor control of lower limb movements in simulated gait.
Adult
Aged
Aging
/ physiology
Ankle
/ physiology
Brain Mapping
Female
Foot
/ physiology
Frontal Lobe
/ diagnostic imaging
Gait
/ physiology
Humans
Imagination
Lower Extremity
/ physiology
Magnetic Resonance Imaging
Male
Middle Aged
Motor Cortex
/ diagnostic imaging
Movement
/ physiology
Neuropsychological Tests
Parietal Lobe
/ diagnostic imaging
Psychomotor Performance
/ physiology
Walking
/ physiology
Young Adult
fMRI
foot movements
gait motor control
healthy aging
motor imagery
premotor cortex
Journal
Human brain mapping
ISSN: 1097-0193
Titre abrégé: Hum Brain Mapp
Pays: United States
ID NLM: 9419065
Informations de publication
Date de publication:
05 2020
05 2020
Historique:
received:
19
07
2019
revised:
19
10
2019
accepted:
23
12
2019
pubmed:
11
1
2020
medline:
23
9
2021
entrez:
11
1
2020
Statut:
ppublish
Résumé
Gait control becomes more demanding in healthy older adults, yet what cognitive or motor process leads to this age-related change is unknown. The present study aimed to investigate whether it might depend on specific decay in the quality of gait motor representation and/or a more general reduction in the efficiency of lower limb motor control. Younger and older healthy participants performed in fMRI a virtual walking paradigm that combines motor imagery (MI) of walking and standing on the spot with the presence (Dynamic Motor Imagery condition, DMI) or absence (pure MI condition) of overtly executed ankle dorsiflexion. Gait imagery was aided by the concomitant observation of moving videos simulating a stroll in the park from a first-person perspective. Behaviorally, older participants showed no sign of evident depletion in the quality of gait motor representations, and absence of between-group differences in the neural correlates of MI. However, while younger participants showed increased frontoparietal activity during DMI, older participants displayed stronger activation of premotor areas when controlling the pure execution of ankle dorsiflexion, regardless of the imagery task. These data suggest that reduced automaticity of lower limb motor control in healthy older subjects leads to the recruitment of additional premotor resources even in the absence of basic gait functional disabilities.
Identifiants
pubmed: 31922648
doi: 10.1002/hbm.24919
pmc: PMC7267909
doi:
Types de publication
Journal Article
Research Support, Non-U.S. Gov't
Langues
eng
Sous-ensembles de citation
IM
Pagination
1889-1903Informations de copyright
© 2020 The Authors. Human Brain Mapping published by Wiley Periodicals, Inc.
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