Controlling protein interactions in blood for effective liver immunosuppressive therapy by silica nanocapsules.


Journal

Nanoscale
ISSN: 2040-3372
Titre abrégé: Nanoscale
Pays: England
ID NLM: 101525249

Informations de publication

Date de publication:
28 Jan 2020
Historique:
pubmed: 16 1 2020
medline: 21 10 2020
entrez: 16 1 2020
Statut: ppublish

Résumé

Immunosuppression with glucocorticoids is a common treatment for autoimmune liver diseases and after liver transplant, which is however associated with severe side-effects. Targeted delivery of glucocorticoids to inflammatory cells, e.g. liver macrophages and Kupffer cells, is a promising approach for minimizing side effects. Herein, we prepare core-shell silica nanocapsules (SiO

Identifiants

pubmed: 31939969
doi: 10.1039/c9nr09879h
doi:

Substances chimiques

Colloids 0
Cytokines 0
Immunosuppressive Agents 0
Nanocapsules 0
Silicon Dioxide 7631-86-9
Dexamethasone 7S5I7G3JQL

Types de publication

Journal Article

Langues

eng

Sous-ensembles de citation

IM

Pagination

2626-2637

Auteurs

Shuai Jiang (S)

Max Planck Institute for Polymer Research, Ackermannweg 10, 55128 Mainz, Germany. landfester@mpip-mainz.mpg.de daniel.crespy@vistec.ac.th.

Domenik Prozeller (D)

Max Planck Institute for Polymer Research, Ackermannweg 10, 55128 Mainz, Germany. landfester@mpip-mainz.mpg.de daniel.crespy@vistec.ac.th.

Jorge Pereira (J)

Max Planck Institute for Polymer Research, Ackermannweg 10, 55128 Mainz, Germany. landfester@mpip-mainz.mpg.de daniel.crespy@vistec.ac.th.

Johanna Simon (J)

Max Planck Institute for Polymer Research, Ackermannweg 10, 55128 Mainz, Germany. landfester@mpip-mainz.mpg.de daniel.crespy@vistec.ac.th and Dermatology Clinic, University Medical Center of the Johannes Gutenberg-University, Langenbeckstr. 1, 55131 Mainz, Germany.

Shen Han (S)

Max Planck Institute for Polymer Research, Ackermannweg 10, 55128 Mainz, Germany. landfester@mpip-mainz.mpg.de daniel.crespy@vistec.ac.th.

Sebastian Wirsching (S)

Children's Hospital, University Medical Center of the Johannes-Gutenberg University, Mainz, Germany.

Michael Fichter (M)

Children's Hospital, University Medical Center of the Johannes-Gutenberg University, Mainz, Germany.

Milagro Mottola (M)

Max Planck Institute for Polymer Research, Ackermannweg 10, 55128 Mainz, Germany. landfester@mpip-mainz.mpg.de daniel.crespy@vistec.ac.th.

Ingo Lieberwirth (I)

Max Planck Institute for Polymer Research, Ackermannweg 10, 55128 Mainz, Germany. landfester@mpip-mainz.mpg.de daniel.crespy@vistec.ac.th.

Svenja Morsbach (S)

Max Planck Institute for Polymer Research, Ackermannweg 10, 55128 Mainz, Germany. landfester@mpip-mainz.mpg.de daniel.crespy@vistec.ac.th.

Volker Mailänder (V)

Max Planck Institute for Polymer Research, Ackermannweg 10, 55128 Mainz, Germany. landfester@mpip-mainz.mpg.de daniel.crespy@vistec.ac.th and Dermatology Clinic, University Medical Center of the Johannes Gutenberg-University, Langenbeckstr. 1, 55131 Mainz, Germany.

Stephan Gehring (S)

Children's Hospital, University Medical Center of the Johannes-Gutenberg University, Mainz, Germany.

Daniel Crespy (D)

Max Planck Institute for Polymer Research, Ackermannweg 10, 55128 Mainz, Germany. landfester@mpip-mainz.mpg.de daniel.crespy@vistec.ac.th and Department of Materials Science and Engineering, School of Molecular Science and Engineering, Vidyasirimedhi Institute of Science and Technology (VISTEC), Rayong 21210, Thailand.

Katharina Landfester (K)

Max Planck Institute for Polymer Research, Ackermannweg 10, 55128 Mainz, Germany. landfester@mpip-mainz.mpg.de daniel.crespy@vistec.ac.th.

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Classifications MeSH