Pathogen-Specific Impacts of the 2011-2012 La Niña-Associated Floods on Enteric Infections in the MAL-ED Peru Cohort: A Comparative Interrupted Time Series Analysis.


Journal

International journal of environmental research and public health
ISSN: 1660-4601
Titre abrégé: Int J Environ Res Public Health
Pays: Switzerland
ID NLM: 101238455

Informations de publication

Date de publication:
12 01 2020
Historique:
received: 04 12 2019
revised: 07 01 2020
accepted: 09 01 2020
entrez: 17 1 2020
pubmed: 17 1 2020
medline: 18 7 2020
Statut: epublish

Résumé

Extreme floods pose multiple direct and indirect health risks. These risks include contamination of water, food, and the environment, often causing outbreaks of diarrheal disease. Evidence regarding the effects of flooding on individual diarrhea-causing pathogens is limited, but is urgently needed in order to plan and implement interventions and prioritize resources before climate-related disasters strike. This study applied a causal inference approach to data from a multisite study that deployed broadly inclusive diagnostics for numerous high-burden common enteropathogens. Relative risks (RRs) of infection with each pathogen during a flooding disaster that occurred at one of the sites-Loreto, Peru-were calculated from generalized linear models using a comparative interrupted time series framework with the other sites as a comparison group and adjusting for background seasonality. During the early period of the flood, increased risk of heat-stable enterotoxigenic

Identifiants

pubmed: 31940920
pii: ijerph17020487
doi: 10.3390/ijerph17020487
pmc: PMC7013961
pii:
doi:

Types de publication

Comparative Study Journal Article Research Support, N.I.H., Extramural Research Support, Non-U.S. Gov't Research Support, U.S. Gov't, Non-P.H.S.

Langues

eng

Sous-ensembles de citation

IM

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Auteurs

Josh Colston (J)

Division of Infectious Diseases and International Health, University of Virginia School of Medicine, Charlottesville, VA 22903, USA.

Maribel Paredes Olortegui (M)

Asociación Benéfica Prisma, Iquitos 16006, Peru.

Benjamin Zaitchik (B)

Department of Earth and Planetary Sciences, Johns Hopkins Krieger School of Arts and Sciences, Baltimore, MD 21218, USA.

Pablo Peñataro Yori (P)

Division of Infectious Diseases and International Health, University of Virginia, Charlottesville, VA 22903, USA.

Gagandeep Kang (G)

Christian Medical College, Vellore 632004, India.

Tahmeed Ahmed (T)

Nutrition & Clinical Services Division, International Centre for Diarrhoeal Disease Research, Bangladesh (icddr,b), Dhaka 1213, Bangladesh.

Pascal Bessong (P)

University of Venda, Thohoyandou 0950, South Africa.

Esto Mduma (E)

Haydom Global Health Institute, Haydom P.O. Box 9000, Tanzania.

Zulfiqar Bhutta (Z)

Department of Pediatrics and Child Health, Aga Khan University, Karachi 74800, Pakistan.

Prakash Sunder Shrestha (P)

Department of Child Health, Institute of Medicine of Tribhuvan University, Kirtipur 44618, Nepal.

Aldo Lima (A)

Federal University of Ceará, Fortaleza 60020-181, Brazil.

Margaret Kosek (M)

Division of Infectious Diseases and International Health, University of Virginia, Charlottesville, VA 22903, USA.

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Classifications MeSH