Pseudoangiomatous Stromal Hyperplasia (PASH) of the Breast: An Uncommon Finding in an Uncommon Patient.
Journal
The American journal of case reports
ISSN: 1941-5923
Titre abrégé: Am J Case Rep
Pays: United States
ID NLM: 101489566
Informations de publication
Date de publication:
16 Jan 2020
16 Jan 2020
Historique:
entrez:
17
1
2020
pubmed:
17
1
2020
medline:
22
7
2020
Statut:
epublish
Résumé
BACKGROUND Pseudoangiomatous stromal hyperplasia (PASH) is an uncommon benign breast lesion. CASE REPORT PASH is reported in a young female in treatment for neurological diseases with multi-drug therapy (clonazepam, valproate and risperidone). Her menstrual cycles are irregular, and she reached menarche very late. CONCLUSIONS The higher PASH prevalence in premenopausal woman (the majority of whom are actively taking oral contraceptive pills), in 24% to 47% of men with gynecomastia and during pregnancy supports a hormonal etiology; the interaction between clonazepam, valproate, risperidone and progesterone could increase the level of progesterone that could stimulate PASH growth.
Identifiants
pubmed: 31941879
pii: 919856
doi: 10.12659/AJCR.919856
pmc: PMC6979473
doi:
Substances chimiques
Progesterone
4G7DS2Q64Y
Types de publication
Case Reports
Langues
eng
Sous-ensembles de citation
IM
Pagination
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