Genetic Intersections of Language and Neuropsychiatric Conditions.
Genetics
Language
Neurodevelopment
Psychiatry
Journal
Current psychiatry reports
ISSN: 1535-1645
Titre abrégé: Curr Psychiatry Rep
Pays: United States
ID NLM: 100888960
Informations de publication
Date de publication:
17 01 2020
17 01 2020
Historique:
entrez:
19
1
2020
pubmed:
19
1
2020
medline:
15
8
2020
Statut:
epublish
Résumé
To better understand the shared basis of language and mental health, this review examines the behavioral and neurobiological features of aberrant language in five major neuropsychiatric conditions. Special attention is paid to genes implicated in both language and neuropsychiatric disorders, as they reveal biological domains likely to underpin the processes controlling both. Abnormal language and communication are common manifestations of neuropsychiatric conditions, and children with impaired language are more likely to develop psychiatric disorders than their peers. Major themes in the genetics of both language and psychiatry include master transcriptional regulators, like FOXP2; key developmental regulators, like AUTS2; and mediators of neurotransmission, like GRIN2A and CACNA1C.
Identifiants
pubmed: 31953567
doi: 10.1007/s11920-019-1123-z
pii: 10.1007/s11920-019-1123-z
doi:
Types de publication
Journal Article
Review
Langues
eng
Sous-ensembles de citation
IM
Pagination
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