Association of Local Epicardial Adipose Tissue Depots and Left Ventricular Diastolic Performance in Patients With Preserved Left Ventricular Ejection Fraction.
Adipose Tissue
/ diagnostic imaging
Adiposity
Aged
Aged, 80 and over
Computed Tomography Angiography
Coronary Angiography
Cross-Sectional Studies
Diastole
Echocardiography, Doppler, Pulsed
Female
Humans
Male
Middle Aged
Multidetector Computed Tomography
Pericardium
/ diagnostic imaging
Retrospective Studies
Risk Factors
Stroke Volume
Ventricular Dysfunction, Left
/ diagnostic imaging
Ventricular Function, Left
Epicardial adipose tissue
Left ventricular diastolic dysfunction
Obesity
Journal
Circulation journal : official journal of the Japanese Circulation Society
ISSN: 1347-4820
Titre abrégé: Circ J
Pays: Japan
ID NLM: 101137683
Informations de publication
Date de publication:
24 01 2020
24 01 2020
Historique:
pubmed:
21
1
2020
medline:
21
10
2020
entrez:
21
1
2020
Statut:
ppublish
Résumé
Although full-volume quantification of epicardial adipose tissue (EAT) is a predictor of LV diastolic dysfunction (LVDD), how localized EAT depots are linked to LVDD remains unclear. We evaluated the effect of local EAT depots on LV diastolic function parameters in patients with preserved LV ejection fraction (LVEF).Methods and Results:From 423 consecutive patients who underwent cardiac CT angiography, we recruited 252 with sinus rhythm and normal LVEF. The EAT volume index (EATV/body surface area) and the localized EAT thickness around the right coronary artery (EAT Localized EAT depots are linked to altered mitral annular motion. Further study is warranted to clarify whether localized EAT depots are functionally linked to the clinical manifestations of LVDD.
Sections du résumé
BACKGROUND
Although full-volume quantification of epicardial adipose tissue (EAT) is a predictor of LV diastolic dysfunction (LVDD), how localized EAT depots are linked to LVDD remains unclear. We evaluated the effect of local EAT depots on LV diastolic function parameters in patients with preserved LV ejection fraction (LVEF).Methods and Results:From 423 consecutive patients who underwent cardiac CT angiography, we recruited 252 with sinus rhythm and normal LVEF. The EAT volume index (EATV/body surface area) and the localized EAT thickness around the right coronary artery (EAT
CONCLUSIONS
Localized EAT depots are linked to altered mitral annular motion. Further study is warranted to clarify whether localized EAT depots are functionally linked to the clinical manifestations of LVDD.
Identifiants
pubmed: 31956209
doi: 10.1253/circj.CJ-19-0793
doi:
Types de publication
Journal Article
Langues
eng
Sous-ensembles de citation
IM
Pagination
203-216Commentaires et corrections
Type : CommentIn