Synthesis and Preclinical Evaluation of an

Alzheimer Disease / metabolism Animals Brain / metabolism Epilepsy / diagnosis Humans Membrane Glycoproteins / metabolism Nerve Tissue Proteins / metabolism Primates / metabolism Synaptic Vesicles / metabolism
Alzheimer’s disease PET Parkinson’s disease SV2A fluorine-18 non-human primate

Journal

ACS chemical neuroscience
ISSN: 1948-7193
Titre abrégé: ACS Chem Neurosci
Pays: United States
ID NLM: 101525337

Informations de publication

Date de publication:
19 02 2020
Historique:
pubmed: 22 1 2020
medline: 4 3 2021
entrez: 22 1 2020
Statut: ppublish

Résumé

Synaptic vesicle glycoprotein 2A (SV2A) is a 12-pass transmembrane glycoprotein ubiquitously expressed in presynaptic vesicles.

Identifiants

DOI: 10.1021/acschemneuro.9b00618 PMID: 31961649
pubmed: 31961649
doi: 10.1021/acschemneuro.9b00618
doi:

Substances chimiques

Membrane Glycoproteins 0
Nerve Tissue Proteins 0

Types de publication

Journal Article Research Support, N.I.H., Extramural

Langues

eng

Sous-ensembles de citation

IM

Pagination

592-603

Subventions

Organisme : NIBIB NIH HHS
ID : K01 EB023312
Pays : United States
Organisme : NIA NIH HHS
ID : R01 AG058773
Pays : United States
Organisme : NIA NIH HHS
ID : R01 AG052560
Pays : United States

Auteurs

Zhengxin Cai (Z)

PET Center, Department of Radiology and Biomedical Imaging , Yale University , New Haven , Connecticut 06520 , United States.
ORCID: 0000-0002-2005-6760

Songye Li (S)

PET Center, Department of Radiology and Biomedical Imaging , Yale University , New Haven , Connecticut 06520 , United States.
ORCID: 0000-0002-6096-8756

Wenjie Zhang (W)

PET Center, Department of Radiology and Biomedical Imaging , Yale University , New Haven , Connecticut 06520 , United States.
Department of Nuclear Medicine, Laboratory of Clinical Nuclear Medicine , West China Hospital, Sichuan University , Chengdu , Sichuan 610041 , China.

Richard Pracitto (R)

PET Center, Department of Radiology and Biomedical Imaging , Yale University , New Haven , Connecticut 06520 , United States.

Xiaoai Wu (X)

PET Center, Department of Radiology and Biomedical Imaging , Yale University , New Haven , Connecticut 06520 , United States.
Department of Nuclear Medicine, Laboratory of Clinical Nuclear Medicine , West China Hospital, Sichuan University , Chengdu , Sichuan 610041 , China.

Evan Baum (E)

PET Center, Department of Radiology and Biomedical Imaging , Yale University , New Haven , Connecticut 06520 , United States.
ORCID: 0000-0002-0998-1293

Sjoerd J Finnema (SJ)

PET Center, Department of Radiology and Biomedical Imaging , Yale University , New Haven , Connecticut 06520 , United States.

Daniel Holden (D)

PET Center, Department of Radiology and Biomedical Imaging , Yale University , New Haven , Connecticut 06520 , United States.

Takuya Toyonaga (T)

PET Center, Department of Radiology and Biomedical Imaging , Yale University , New Haven , Connecticut 06520 , United States.

Shu-Fei Lin (SF)

PET Center, Department of Radiology and Biomedical Imaging , Yale University , New Haven , Connecticut 06520 , United States.

Marcel Lindemann (M)

PET Center, Department of Radiology and Biomedical Imaging , Yale University , New Haven , Connecticut 06520 , United States.

Anupama Shirali (A)

PET Center, Department of Radiology and Biomedical Imaging , Yale University , New Haven , Connecticut 06520 , United States.

David C Labaree (DC)

PET Center, Department of Radiology and Biomedical Imaging , Yale University , New Haven , Connecticut 06520 , United States.

Jim Ropchan (J)

PET Center, Department of Radiology and Biomedical Imaging , Yale University , New Haven , Connecticut 06520 , United States.

Nabeel Nabulsi (N)

PET Center, Department of Radiology and Biomedical Imaging , Yale University , New Haven , Connecticut 06520 , United States.

Richard E Carson (RE)

PET Center, Department of Radiology and Biomedical Imaging , Yale University , New Haven , Connecticut 06520 , United States.

Yiyun Huang (Y)

PET Center, Department of Radiology and Biomedical Imaging , Yale University , New Haven , Connecticut 06520 , United States.

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Classifications MeSH

questionsmedicales.fr › Troubles mentaux › Troubles neurocognitifs › Démence › Maladie d'Alzheimer › Synthesis and Preclinical Evaluation of an
questionsmedicales.fr › Eucaryotes › Animaux › Synthesis and Preclinical Evaluation of an
questionsmedicales.fr › Système nerveux › Système nerveux central › Encéphale › Synthesis and Preclinical Evaluation of an
questionsmedicales.fr › Maladies du système nerveux › Maladies du système nerveux central › Encéphalopathies › Épilepsie › Synthesis and Preclinical Evaluation of an
questionsmedicales.fr › Eucaryotes › Animaux › Chordés › Vertébrés › Mammifères › Eutheria › Primates › Haplorhini › Catarrhini › Hominidae › Humains › Synthesis and Preclinical Evaluation of an
questionsmedicales.fr › Acides aminés, peptides et protéines › Protéines › Protéines membranaires › Glycoprotéines membranaires › Synthesis and Preclinical Evaluation of an
questionsmedicales.fr › Acides aminés, peptides et protéines › Protéines › Protéines de tissu nerveux › Synthesis and Preclinical Evaluation of an
questionsmedicales.fr › Eucaryotes › Animaux › Chordés › Vertébrés › Mammifères › Eutheria › Primates › Synthesis and Preclinical Evaluation of an
questionsmedicales.fr › Cellules › Structures cellulaires › Espace intracellulaire › Cytoplasme › Structures cytoplasmiques › Organites › Vésicules cytoplasmiques › Vésicules de transport › Vésicules de sécrétion › Vésicules synaptiques › Synthesis and Preclinical Evaluation of an