Co-circulation of multiple enterovirus D68 subclades, including a novel B3 cluster, across Europe in a season of expected low prevalence, 2019/20.


Journal

Euro surveillance : bulletin Europeen sur les maladies transmissibles = European communicable disease bulletin
ISSN: 1560-7917
Titre abrégé: Euro Surveill
Pays: Sweden
ID NLM: 100887452

Informations de publication

Date de publication:
01 2020
Historique:
entrez: 23 1 2020
pubmed: 23 1 2020
medline: 12 9 2020
Statut: ppublish

Résumé

Enterovirus D68 (EV-D68) was detected in 93 patients from five European countries between 1 January 2019 and 15 January 2020, a season with expected low circulation. Patients were primarily children (n = 67, median age: 4 years), 59 patients required hospitalisation and five had severe neurologic manifestations. Phylogenetic analysis revealed two clusters in the B3 subclade and subclade A2/D. This circulation of EV-D68 associated with neurological manifestations stresses the importance of surveillance and diagnostics beyond expected peak years.

Identifiants

pubmed: 31964463
doi: 10.2807/1560-7917.ES.2020.25.2.1900749
pmc: PMC6976881
doi:

Types de publication

Journal Article

Langues

eng

Sous-ensembles de citation

IM

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Auteurs

Sofie Elisabeth Midgley (SE)

Department for Virus and Microbiological Special Diagnostics, Statens Serum Institut, Copenhagen, Denmark.

Kimberley Benschop (K)

Centre for Infectious Disease Research, Diagnostics and Laboratory Surveillance, National Institute for Public Health and the Environment (RIVM), Bilthoven, the Netherlands.

Robert Dyrdak (R)

Department of Clinical Microbiology, Karolinska University Hospital, Stockholm, Sweden.
Department of Microbiology, Tumor and Cell Biology, Karolinska Institutet, Stockholm, Sweden.

Audrey Mirand (A)

CHU Clermont-Ferrand, Centre National de Référence des entérovirus et parechovirus - Laboratoire Associé, Laboratoire de Virologie, Clermont-Ferrand, France.
Université Clermont Auvergne, CNRS, Laboratoire Microorganismes: Génome et Environnement, Clermont-Ferrand, France.

Jean-Luc Bailly (JL)

Université Clermont Auvergne, CNRS, Laboratoire Microorganismes: Génome et Environnement, Clermont-Ferrand, France.

Sibylle Bierbaum (S)

Institute of Virology, University of Freiburg, Freiburg, Germany.

Stefan Buderus (S)

Department of General Pediatrics, St.-Marien-Hospital, Bonn, Germany.

Sindy Böttcher (S)

National Reference Center for Poliomyelitis and Enteroviruses, Robert Koch-Institute, Berlin, Germany.

Anna-Maria Eis-Hübinger (AM)

Institute of Virology, University of Bonn Medical Center, Bonn, Germany.

Mario Hönemann (M)

Institute of Virology, University of Leipzig, Leipzig, Germany.

Veronika Vorobieva Jensen (VV)

Department for Virus and Microbiological Special Diagnostics, Statens Serum Institut, Copenhagen, Denmark.

Ulla Birgitte Hartling (UB)

Department of Paediatrics, Aarhus University Hospital, Aarhus, Denmark.

Cécile Henquell (C)

CHU Clermont-Ferrand, Centre National de Référence des entérovirus et parechovirus - Laboratoire Associé, Laboratoire de Virologie, Clermont-Ferrand, France.

Marcus Panning (M)

Institute of Virology, University of Freiburg, Freiburg, Germany.

Marianne Kragh Thomsen (MK)

Department of Clinical Microbiology, Aarhus University Hospital, Aarhus, Denmark.

Emma B Hodcroft (EB)

Biozentrum, University of Basel, Basel, Switzerland.
Swiss Institute of Bioinformatics, Basel, Switzerland.

Adam Meijer (A)

Centre for Infectious Disease Research, Diagnostics and Laboratory Surveillance, National Institute for Public Health and the Environment (RIVM), Bilthoven, the Netherlands.

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Classifications MeSH