Phase I, Dose-Escalating Study of the Safety and Pharmacokinetics of Inhaled Dry-Powder Vancomycin (AeroVanc) in Volunteers and Patients with Cystic Fibrosis: a New Approach to Therapy for Methicillin-Resistant Staphylococcus aureus.
Administration, Inhalation
Adolescent
Adult
Anti-Bacterial Agents
/ blood
Cystic Fibrosis
/ blood
Dry Powder Inhalers
Female
Forced Expiratory Volume
/ drug effects
Humans
Male
Methicillin-Resistant Staphylococcus aureus
/ drug effects
Microbial Sensitivity Tests
Middle Aged
Opportunistic Infections
/ blood
Patient Safety
Powders
Staphylococcal Infections
/ blood
Vancomycin
/ blood
MRSA
cystic fibrosis
inhaled
vancomycin
Journal
Antimicrobial agents and chemotherapy
ISSN: 1098-6596
Titre abrégé: Antimicrob Agents Chemother
Pays: United States
ID NLM: 0315061
Informations de publication
Date de publication:
21 02 2020
21 02 2020
Historique:
received:
30
08
2019
accepted:
01
01
2020
pubmed:
23
1
2020
medline:
19
12
2020
entrez:
23
1
2020
Statut:
epublish
Résumé
Methicillin-resistant
Identifiants
pubmed: 31964790
pii: AAC.01776-19
doi: 10.1128/AAC.01776-19
pmc: PMC7038285
pii:
doi:
Substances chimiques
Anti-Bacterial Agents
0
Powders
0
Vancomycin
6Q205EH1VU
Types de publication
Clinical Trial, Phase I
Journal Article
Langues
eng
Sous-ensembles de citation
IM
Informations de copyright
Copyright © 2020 American Society for Microbiology.
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