c-MAF deletion in adult C57BL/6J mice induces cataract formation and abnormal differentiation of lens fiber cells.

Animals Cataract / genetics Gene Deletion Lens, Crystalline / pathology Mice Mice, Inbred C57BL Proto-Oncogene Proteins c-maf / genetics
c-MAF cataract lens epithelial cell lens fiber cell

Journal

Experimental animals
ISSN: 1881-7122
Titre abrégé: Exp Anim
Pays: Japan
ID NLM: 9604830

Informations de publication

Date de publication:
24 Apr 2020
Historique:
pubmed: 24 1 2020
medline: 5 8 2020
entrez: 24 1 2020
Statut: ppublish

Résumé

The transcription factor c-MAF is a member of the large MAF family, members of which possess transactivation and bZIP domains. c-MAF plays an important role in lens formation, T-lymphocyte differentiation, hypertrophic chondrocyte differentiation, and kidney development in mouse embryos. However, because homozygous deletion of c-Maf in C57BL/6J mice causes embryonic lethality, the functions of c-MAF in adult mice remain largely uninvestigated. To address this issue, we generated c-Maf floxed (c-Maf

Identifiants

DOI: 10.1538/expanim.19-0137 PMID: 31969519 PMC: PMC7220708
pubmed: 31969519
doi: 10.1538/expanim.19-0137
pmc: PMC7220708
doi:

Substances chimiques

Maf protein, mouse 0
Proto-Oncogene Proteins c-maf 0

Types de publication

Journal Article

Langues

eng

Sous-ensembles de citation

IM

Pagination

242-249

Références

J Biol Chem. 1999 Jul 2;274(27):19254-60
pubmed: 10383433
Trends Biochem Sci. 1997 Nov;22(11):437-41
pubmed: 9397686
Mol Vis. 2007 Oct 18;13:2019-22
pubmed: 17982426
Science. 1998 Apr 3;280(5360):115-8
pubmed: 9525857
Proc Natl Acad Sci U S A. 1997 Feb 4;94(3):884-9
pubmed: 9023351
J Biochem. 1993 Mar;113(3):343-9
pubmed: 8387481
Development. 2009 Aug;136(15):2567-78
pubmed: 19570848
Mol Vis. 2010 Mar 03;16:341-52
pubmed: 20216939
Proc Natl Acad Sci U S A. 1999 Mar 30;96(7):3781-5
pubmed: 10097114
Hum Mol Genet. 2002 Jan 1;11(1):33-42
pubmed: 11772997
J Biol Chem. 2013 Apr 19;288(16):11436-47
pubmed: 23479732
Blood. 2011 Aug 4;118(5):1374-85
pubmed: 21628412
Mol Vis. 1997 May 07;3:5
pubmed: 9238094
Am J Med Genet A. 2014 May;164A(5):1272-6
pubmed: 24664492
J Exp Med. 1998 Nov 16;188(10):1859-66
pubmed: 9815263
Sci Signal. 2013 Dec 17;6(306):ra110
pubmed: 24345681
Dev Biol. 2008 Jun 15;318(2):276-88
pubmed: 18455718
Dev Biol. 2003 Oct 1;262(1):51-63
pubmed: 14512017
Am J Med Genet A. 2006 Mar 15;140(6):558-66
pubmed: 16470690
Dev Biol. 2002 Apr 15;244(2):305-18
pubmed: 11944939
Invest Ophthalmol Vis Sci. 2011 Apr 20;52(5):2571-6
pubmed: 21212184
Methods. 2001 May;24(1):71-80
pubmed: 11327805
Biochem Biophys Res Commun. 2004 Aug 6;320(4):1323-7
pubmed: 15249232
Dev Neurosci. 2004;26(5-6):446-55
pubmed: 15855773
Genomics. 2000 Feb 1;63(3):314-20
pubmed: 10704279
PLoS One. 2015 May 07;10(5):e0125304
pubmed: 25951169
J Clin Invest. 2010 Oct;120(10):3455-65
pubmed: 20877012

Auteurs

Mitsunori Fujino (M)

Department of Anatomy and Embryology, Faculty of Medicine, University of Tsukuba, 1-1-1 Tennodai, Tsukuba, Ibaraki 305-8575, Japan.
Ph.D. Program in Human Biology, School of Integrative and Global Majors, University of Tsukuba, 1-1-1 Tennodai, Tsukuba, Ibaraki 305-8575, Japan.

Asuka Tagami (A)

Department of Anatomy and Embryology, Faculty of Medicine, University of Tsukuba, 1-1-1 Tennodai, Tsukuba, Ibaraki 305-8575, Japan.

Masami Ojima (M)

Laboratory Animal Resource Center (LARC), University of Tsukuba, 1-1-1 Tennodai, Tsukuba, Ibaraki 305-8575, Japan.

Seiya Mizuno (S)

Laboratory Animal Resource Center (LARC), University of Tsukuba, 1-1-1 Tennodai, Tsukuba, Ibaraki 305-8575, Japan.

Ahmed M Abdellatif (AM)

Department of Anatomy and Embryology, Faculty of Veterinary Medicine, Mansoura University, Mansoura 35516, Egypt.

Akihiro Kuno (A)

Department of Anatomy and Embryology, Faculty of Medicine, University of Tsukuba, 1-1-1 Tennodai, Tsukuba, Ibaraki 305-8575, Japan.

Satoru Takahashi (S)

Department of Anatomy and Embryology, Faculty of Medicine, University of Tsukuba, 1-1-1 Tennodai, Tsukuba, Ibaraki 305-8575, Japan.
Laboratory Animal Resource Center (LARC), University of Tsukuba, 1-1-1 Tennodai, Tsukuba, Ibaraki 305-8575, Japan.
Life Science Center, Tsukuba Advanced Research Alliance (TARA), University of Tsukuba, 1-1-1 Tennodai, Tsukuba, Ibaraki 305-8575, Japan.
International Institute for Integrative Sleep Medicine (WPI-IIIS), University of Tsukuba, 1-1-1 Tennodai, Tsukuba, Ibaraki 305-8575, Japan.
Transborder Medical Research Center, Faculty of Medicine, University of Tsukuba, 1-1-1 Tennodai, Tsukuba, Ibaraki 305-8575, Japan.

Articles similaires

Evaluating the efficacy of telesurgery with dual console SSI Mantra Surgical Robotic System: experiment on animal model and clinical trials.

Sudhir Prem Srivastava, Vishwajyoti Pascual Srivastava, Avinesh Singh et al.
1.00
Robotic Surgical Procedures Animals Humans Telemedicine Models, Animal

Odour generalisation and detection dog training.

Lyn Caldicott, Thomas W Pike, Helen E Zulch et al.
1.00
Animals Odorants Dogs Generalization, Psychological Smell

FBXO22 inhibits colitis and colorectal carcinogenesis by regulating the degradation of the S2448-phosphorylated form of mTOR.

Minle Li, Xuan Chen, Pengfei Qu et al.
1.00
Animals TOR Serine-Threonine Kinases Colorectal Neoplasms Colitis Mice

Use of organic material provided by an automatic enrichment device by weaner pigs and its influence on tail lesions.

Philipp Heseker, Jeanette Probst, Stefanie Ammer et al.
1.00
Animals Tail Swine Behavior, Animal Animal Husbandry

Classifications MeSH

questionsmedicales.fr › Eucaryotes › Animaux › c-MAF deletion in adult C57BL/6J mice induces...
questionsmedicales.fr › Maladies de l'oeil › Maladies du cristallin › Cataracte › c-MAF deletion in adult C57BL/6J mice induces...
questionsmedicales.fr › Phénomènes génétiques › Mutagenèse › Délétion de séquence › Délétion de gène › c-MAF deletion in adult C57BL/6J mice induces...
questionsmedicales.fr › Organes des sens › Oeil › Pôle antérieur du bulbe oculaire › Cristallin › c-MAF deletion in adult C57BL/6J mice induces...
questionsmedicales.fr › Eucaryotes › Animaux › Chordés › Vertébrés › Mammifères › Eutheria › Rodentia › Muridae › Murinae › Souris › c-MAF deletion in adult C57BL/6J mice induces...
questionsmedicales.fr › Eucaryotes › Animaux › Chordés › Vertébrés › Mammifères › Eutheria › Rodentia › Muridae › Murinae › Souris › Lignées consanguines de souris › Souris de lignée C57BL › c-MAF deletion in adult C57BL/6J mice induces...
questionsmedicales.fr › Acides aminés, peptides et protéines › Protéines › Facteurs de transcription › Facteurs de transcription à motif basique et à glissière à leucines › Facteurs de transcription Maf › Grandes protéines des facteurs de transcription Maf › Protéines proto-oncogènes c-maf › c-MAF deletion in adult C57BL/6J mice induces...