Equation Derivation of the Probability Distribution of IBS Score among Full Sibling Pairs.
forensic genetics; full sibling; identity by state; binomial distribution; probability
Journal
Fa yi xue za zhi
ISSN: 1004-5619
Titre abrégé: Fa Yi Xue Za Zhi
Pays: China
ID NLM: 9426151
Informations de publication
Date de publication:
Dec 2019
Dec 2019
Historique:
received:
16
11
2018
entrez:
24
1
2020
pubmed:
24
1
2020
medline:
6
2
2020
Statut:
ppublish
Résumé
Objective To derive the general equation of the probability distribution of identity by state （IBS） score among biological full sibling pairs by calculating STR allele frequency. Methods Based on the Mendelian genetics law and the hypothesis that parents of biological full siblings （FS） were unrelated individuals, the 推导IBS评分在全同胞对人群中概率分布的计算公式. 目的 推导通过STR等位基因频率计算生物学全同胞对间状态一致性（identity by state，IBS）评分概率分布的通用计算公式。 方法 依据孟德尔遗传规律和生物学全同胞（full sibling，FS）的父母为无关个体这一假设，推导得到不同基因型组合的无关个体生育两名子代时，子代不同基因型组合的 法医遗传学；全同胞；状态一致性；二项分布；概率.
Autres résumés
Type: Publisher
(chi)
推导IBS评分在全同胞对人群中概率分布的计算公式.
Identifiants
pubmed: 31970950
pii: j/6/657
doi: 10.12116/j.issn.1004-5619.2019.06.003
doi:
Types de publication
Journal Article
Langues
eng
chi
Sous-ensembles de citation
IM
Pagination
657-661Informations de copyright
Copyright© by the Editorial Department of Journal of Forensic Medicine.
Déclaration de conflit d'intérêts
The authors of this article and the planning committee members and staff have no relevant financial relationships with commercial interests to disclose.