Cryoballoon ablation for gastric pouch and/or outlet reduction in patients with weight regain post Roux-en-Y gastric bypass.
Journal
Endoscopy
ISSN: 1438-8812
Titre abrégé: Endoscopy
Pays: Germany
ID NLM: 0215166
Informations de publication
Date de publication:
03 2020
03 2020
Historique:
pubmed:
25
1
2020
medline:
16
2
2021
entrez:
25
1
2020
Statut:
ppublish
Résumé
Cryoballoon ablation could induce stricture formation to achieve outlet and pouch reduction in patients regaining weight after Roux-en-Y gastric bypass (RYGB). This pilot study aimed to assess technical feasibility and short-term efficacy. A retrospective chart review (January - November 2018) at two academic centers identified patients with weight regain post-RYGB, treated with cryoablation if pouch > 4 cm and/or outlet > 15 mm. Patients were scheduled for surveillance endoscopies at 8 weeks. 22 patients presented 10.5 years (SD 4.42) post-RYGB with weight regain of 30.9 kg (SD 13.7). Technical success was 89.5 % for outlet ablation and 93.0 % for pouch ablation. From baseline to 8 weeks, the outlet was reduced from 24.1 mm (95 % confidence interval [CI] 19.8 to 28.5) to 17.1 mm (95 %CI 13.1 to 21.1; Cryoablation appears technically feasible and effective for outlet and/or pouch reduction in the short term.
Sections du résumé
BACKGROUND
Cryoballoon ablation could induce stricture formation to achieve outlet and pouch reduction in patients regaining weight after Roux-en-Y gastric bypass (RYGB). This pilot study aimed to assess technical feasibility and short-term efficacy.
METHODS
A retrospective chart review (January - November 2018) at two academic centers identified patients with weight regain post-RYGB, treated with cryoablation if pouch > 4 cm and/or outlet > 15 mm. Patients were scheduled for surveillance endoscopies at 8 weeks.
RESULTS
22 patients presented 10.5 years (SD 4.42) post-RYGB with weight regain of 30.9 kg (SD 13.7). Technical success was 89.5 % for outlet ablation and 93.0 % for pouch ablation. From baseline to 8 weeks, the outlet was reduced from 24.1 mm (95 % confidence interval [CI] 19.8 to 28.5) to 17.1 mm (95 %CI 13.1 to 21.1;
CONCLUSION
Cryoablation appears technically feasible and effective for outlet and/or pouch reduction in the short term.
Types de publication
Journal Article
Langues
eng
Sous-ensembles de citation
IM
Pagination
227-230Commentaires et corrections
Type : CommentIn
Type : CommentIn
Informations de copyright
© Georg Thieme Verlag KG Stuttgart · New York.
Déclaration de conflit d'intérêts
Dr. Khashab is on the medical advisory board for Boston Scientific and Olympus America, and is a consultant for Boston Scientific, Olympus America, and Medtronic. Dr. Kalloo is a founding member, equity Holder, and consultant for Apollo Endosurgery. Dr. Kumbhari is a consultant for Medtronic, Pentax, Reshape Lifesciences, Boston Scientific, and Apollo Endosurgery; he also receives research support from ERBE USA and Apollo Endosurgery. Dr. Trindade is a consultant for Pentax Medical and CSA Medical. Dr. Benias is a consultant for Apollo Endosurgery. Dr. Thompson is a consultant for Boston Scientific, Medtronic, USGI Medical, Olympus, Apollo Endosurgery, GI Windows, Aspire Bariatrics, Fractyl, Spatz, and GI Dynamics. Dr. Canto is a consultant for Exigo and has received research grants from Pentax and Endogastric Solutions. All other authors have nothing to disclose.