Effects of Dietary Anaplerotic and Ketogenic Energy Sources on Renal Fatty Acid Oxidation Induced by Clofibrate in Suckling Neonatal Pigs.


Journal

International journal of molecular sciences
ISSN: 1422-0067
Titre abrégé: Int J Mol Sci
Pays: Switzerland
ID NLM: 101092791

Informations de publication

Date de publication:
22 Jan 2020
Historique:
received: 25 11 2019
revised: 17 01 2020
accepted: 20 01 2020
entrez: 26 1 2020
pubmed: 26 1 2020
medline: 7 10 2020
Statut: epublish

Résumé

Maintaining an active fatty acid metabolism is important for renal growth, development, and health. We evaluated the effects of anaplerotic and ketogenic energy sources on fatty acid oxidation during stimulation with clofibrate, a pharmacologic peroxisome proliferator-activated receptor α (PPARα) agonist. Suckling newborn pigs (

Identifiants

pubmed: 31979102
pii: ijms21030726
doi: 10.3390/ijms21030726
pmc: PMC7037708
pii:
doi:

Substances chimiques

Fatty Acids 0
Ketone Bodies 0
PPAR alpha 0
Palmitic Acid 2V16EO95H1
Clofibrate HPN91K7FU3
Carnitine S7UI8SM58A

Types de publication

Journal Article

Langues

eng

Sous-ensembles de citation

IM

Subventions

Organisme : U.S. Department of Agriculture
ID : 2015-67015-23245

Déclaration de conflit d'intérêts

The authors declare no conflict of interest. The funders had no role in the design of the study; in the collection, analyses, or interpretation of data; in the writing of the manuscript, or in the decision to publish the results.

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Auteurs

Xi Lin (X)

Laboratory of Developmental Nutrition, Department of Animal Sciences, North Carolina State University, Raleigh, NC 27695, USA.

Brandon Pike (B)

Laboratory of Developmental Nutrition, Department of Animal Sciences, North Carolina State University, Raleigh, NC 27695, USA.

Jinan Zhao (J)

Laboratory of Developmental Nutrition, Department of Animal Sciences, North Carolina State University, Raleigh, NC 27695, USA.

Yu Fan (Y)

Laboratory of Developmental Nutrition, Department of Animal Sciences, North Carolina State University, Raleigh, NC 27695, USA.

Yongwen Zhu (Y)

Laboratory of Developmental Nutrition, Department of Animal Sciences, North Carolina State University, Raleigh, NC 27695, USA.

Yong Zhang (Y)

Laboratory of Developmental Nutrition, Department of Animal Sciences, North Carolina State University, Raleigh, NC 27695, USA.

Feng Wang (F)

Laboratory of Developmental Nutrition, Department of Animal Sciences, North Carolina State University, Raleigh, NC 27695, USA.

Jack Odle (J)

Laboratory of Developmental Nutrition, Department of Animal Sciences, North Carolina State University, Raleigh, NC 27695, USA.

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Classifications MeSH