OcUGT1-Catalyzing Glycodiversification of Steroids through Glucosylation and Transglucosylation Actions.


Journal

Molecules (Basel, Switzerland)
ISSN: 1420-3049
Titre abrégé: Molecules
Pays: Switzerland
ID NLM: 100964009

Informations de publication

Date de publication:
22 Jan 2020
Historique:
received: 08 01 2020
revised: 20 01 2020
accepted: 21 01 2020
entrez: 26 1 2020
pubmed: 26 1 2020
medline: 24 11 2020
Statut: epublish

Résumé

Steroidal glycosides are important sources of innovative drugs. The increased diversification of steroidal glycosides will expand the probability of discovering active molecules. It is an efficient approach to diversify steroidal glycosides by using steroidal glycosyltransferases. OcUGT1, a uridine diphosphate-d-glucose (UDP-Glc)-dependent glycosyltransferase from

Identifiants

pubmed: 31979165
pii: molecules25030475
doi: 10.3390/molecules25030475
pmc: PMC7036888
pii:
doi:

Substances chimiques

Glucosides 0
Glycosides 0
Steroids 0
Glycosyltransferases EC 2.4.-

Types de publication

Journal Article

Langues

eng

Sous-ensembles de citation

IM

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Auteurs

Yan-Li Xu (YL)

Institute of Materia Medica, Chinese Academy of Medical Sciences & Peking Union Medical College (State Key Laboratory of Bioactive Substance and Function of Natural Medicines & NHC Key Laboratory of Biosynthesis of Natural Products), Beijing 100050, China.

Jian-Qiang Kong (JQ)

Institute of Materia Medica, Chinese Academy of Medical Sciences & Peking Union Medical College (State Key Laboratory of Bioactive Substance and Function of Natural Medicines & NHC Key Laboratory of Biosynthesis of Natural Products), Beijing 100050, China.

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Classifications MeSH