Sacral nerve stimulation increases gastric accommodation in rats: a spinal afferent and vagal efferent pathway.
Afferent Pathways
/ physiology
Animals
Efferent Pathways
/ physiology
Electric Stimulation Therapy
/ methods
Gastric Emptying
Gastroparesis
/ physiopathology
Lumbosacral Plexus
/ physiology
Male
Nitrergic Neurons
/ physiology
Rats, Sprague-Dawley
Reflex
Spinal Nerves
/ physiology
Stomach
/ innervation
Vagus Nerve
/ physiology
gastric accommodation
sacral nerve stimulation
spinal afferent pathway
vagal efferent pathway
Journal
American journal of physiology. Gastrointestinal and liver physiology
ISSN: 1522-1547
Titre abrégé: Am J Physiol Gastrointest Liver Physiol
Pays: United States
ID NLM: 100901227
Informations de publication
Date de publication:
01 03 2020
01 03 2020
Historique:
pubmed:
28
1
2020
medline:
4
8
2020
entrez:
28
1
2020
Statut:
ppublish
Résumé
Impaired gastric accommodation (GA) has been frequently reported in various gastrointestinal diseases. No standard treatment strategy is available for treating impaired GA. We explored the possible effect of sacral nerve stimulation (SNS) on GA and discovered a spinal afferent and vagal efferent mechanism in rats. Sprague-Dawley rats (450-500 g) with a chronically implanted gastric cannula and ECG electrodes were studied in a series of sessions to study:
Identifiants
pubmed: 31984783
doi: 10.1152/ajpgi.00255.2019
doi:
Types de publication
Journal Article
Langues
eng
Sous-ensembles de citation
IM