Italian Association of Clinical Endocrinologists (AME) and Italian AACE Chapter Position Statement for Clinical Practice: Acromegaly - Part 1: Diagnostic and Clinical Issues.

Acromegaly / blood Endocrinologists / standards Human Growth Hormone / blood Humans Insulin-Like Growth Factor I / metabolism Italy / epidemiology Practice Guidelines as Topic / standards Societies, Medical / standards
Acromegaly GH IGF-I comorbidities discrepant pituitary

Journal

Endocrine, metabolic & immune disorders drug targets
ISSN: 2212-3873
Titre abrégé: Endocr Metab Immune Disord Drug Targets
Pays: United Arab Emirates
ID NLM: 101269157

Informations de publication

Date de publication:
2020
Historique:
received: 17 10 2019
revised: 05 12 2019
accepted: 05 12 2019
pubmed: 28 1 2020
medline: 5 8 2021
entrez: 28 1 2020
Statut: ppublish

Résumé

Acromegaly is a rare disease. Improvements in lifespan in these patients have recently been reported due to transsphenoidal surgery (TSS), advances in medical therapy, and strict criteria for defining disease remission. This document reports the opinions of a group of Italian experts who have gathered together their prolonged clinical experience in the diagnostic and therapeutic challenges of acromegaly patients. Both GH and IGF-I (only IGF-I in those treated with Pegvisomant) are needed in the diagnosis and follow-up. Comorbidities (cardio-cerebrovascular disease, sleep apnea, metabolic derangement, neoplasms, and bone/joint disease) should be specifically addressed. Any newly diagnosed patient should be referred to a multidisciplinary team experienced in the treatment of pituitary adenomas.

Identifiants

DOI: 10.2174/1871530320666200127103320 PMID: 31985386 PMC: PMC7579251
pubmed: 31985386
pii: EMIDDT-EPUB-103917
doi: 10.2174/1871530320666200127103320
pmc: PMC7579251
doi:

Substances chimiques

IGF1 protein, human 0
Human Growth Hormone 12629-01-5
Insulin-Like Growth Factor I 67763-96-6

Types de publication

Journal Article Review

Langues

eng

Sous-ensembles de citation

IM

Pagination

1133-1143

Informations de copyright

Copyright© Bentham Science Publishers; For any queries, please email at epub@benthamscience.net.

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Auteurs

Renato Cozzi (R)

Division of Endocrinology, Niguarda Hospital, Milan, Italy.

Maria R Ambrosio (MR)

Section of Endocrinology and Internal Medicine, Department of Medical Sciences, University of Ferrara, Ferrara, Italy.

Roberto Attanasio (R)

IRCCS Orthopedic Institute Galeazzi, Endocrinology Service, Mila, Italy.

Alessandro Bozzao (A)

Neuroradiology, S. Andrea Hospital, NESMOS Department (Neuroscience, Mental Health, Sensorial Organs), Sapienza University of Rome, Rome, Italy.

Laura De Marinis (L)

Pituitary Unit, Department of Endocrinology, Catholic University of the Sacred Heart, School of Medicine, Rome, Italy.

Ernesto De Menis (E)

Department of Internal Medicine, General Hospital, Montebelluna (TV), Italy.

Edoardo Guastamacchia (E)

AME President, University of Bari, Bari, Italy.

Andrea Lania (A)

Department of Biomedical Sciences, IRCCS Humanitas University and Endocrinology Unit, Humanitas Research Hospital, Rozzano, Italy.

Giovanni Lasio (G)

Department of Neurosurgery, Humanitas University and Endocrinology Unit, Humanitas Research Hospital, Rozzano, Italy.

Francesco Logoluso (F)

Endocrinology Unit, Department of Emergency and Organ Transplantation, University Medical School 'Aldo Moro', Bari, Italy.

Pietro Maffei (P)

Department of Medicine (DIMED), 3rd Medical Clinic, Padua University Hospital, Padua, Italy.

Maurizio Poggi (M)

Endocrinology, Department of Clinical and Molecular Medicine, S. Andrea Hospital, Sapienza University of Rome, Rome, Italy.

Vincenzo Toscano (V)

Endocrinology, Department of Clinical and Molecular Medicine, S. Andrea Hospital, Sapienza University of Rome, Rome, Italy.

Michele Zini (M)

Endocrinology Unit, Azienda Ospedaliera S. Maria Nuova IRCCS, Reggio Emilia, Italy.

Philippe Chanson (P)

Endocrinology and Reproductive Diseases, Bicêtre Hospital and Paris-Saclay University 11, France.

Laurence Katznelson (L)

Department of Medicine, Stanford University Hospital, Stanford, CA, United States.

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Classifications MeSH

questionsmedicales.fr › Maladies endocriniennes › Maladies de l'hypophyse › Hyperpituitarisme › Acromégalie › Italian Association of Clinical...
questionsmedicales.fr › Établissements, main d'oeuvre et services de soins de santé › Personnel de santé › Médecins › Endocrinologues › Italian Association of Clinical...
questionsmedicales.fr › Acides aminés, peptides et protéines › Peptides › Hormones peptidiques › Hormones hypophysaires › Hormones antéhypophysaires › Hormone de croissance › Hormone de croissance humaine › Italian Association of Clinical...
questionsmedicales.fr › Eucaryotes › Animaux › Chordés › Vertébrés › Mammifères › Eutheria › Primates › Haplorhini › Catarrhini › Hominidae › Humains › Italian Association of Clinical...
questionsmedicales.fr › Facteurs biologiques › Protéines et peptides de signalisation intercellulaire › Somatomédines › Facteur de croissance IGF-I › Italian Association of Clinical...
questionsmedicales.fr › Régions géographiques › Europe › Italie › Italian Association of Clinical...
questionsmedicales.fr › Qualité, accès, évaluation des soins de santé › Assurance de la qualité des soins de santé › Recommandations comme sujet › Guides de bonnes pratiques cliniques comme sujet › Italian Association of Clinical...
questionsmedicales.fr › Organisations et économie des soins de santé › Organismes › Sociétés › Sociétés médicales › Italian Association of Clinical...