Development of hypocomplementemic urticarial vasculitis during certolizumab pegol treatment for rheumatoid arthritis: A case report.


Journal

Journal of clinical pharmacy and therapeutics
ISSN: 1365-2710
Titre abrégé: J Clin Pharm Ther
Pays: England
ID NLM: 8704308

Informations de publication

Date de publication:
Oct 2020
Historique:
received: 13 10 2019
revised: 12 11 2019
accepted: 06 01 2020
pubmed: 29 1 2020
medline: 11 8 2021
entrez: 29 1 2020
Statut: ppublish

Résumé

Tumour necrosis factor-α-blocking agents potentially cause vasculitis. However, no study has reported on the association between hypocomplementemic urticarial vasculitis (HUV) and certolizumab pegol (CZP) usage. We present the first case of HUV development during CZP treatment for rheumatoid arthritis. Hypocomplementemic urticarial vasculitis improved after CZP was discontinued and the dose of oral prednisolone was increased. Clinicians should be aware about the potential development of HUV during CZP treatment, which is presumed to be safe considering its unique structural characteristics that differ from those of other tumour necrosis factor-α-blocking agents.

Identifiants

pubmed: 31990069
doi: 10.1111/jcpt.13117
doi:

Substances chimiques

Antirheumatic Agents 0
Prednisolone 9PHQ9Y1OLM
Certolizumab Pegol UMD07X179E

Types de publication

Case Reports

Langues

eng

Sous-ensembles de citation

IM

Pagination

1179-1182

Informations de copyright

© 2020 John Wiley & Sons Ltd.

Références

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Auteurs

Yoshiro Horai (Y)

Department of Rheumatology, National Hospital Organization Nagasaki Medical Center, Omura, Japan.
Clinical Research Center, National Hospital Organization Nagasaki Medical Center, Omura, Japan.

Hiroshi Ishikawa (H)

Department of Dermatology, National Hospital Organization Nagasaki Medical Center, Nagasaki, Japan.

Nozomi Iwanaga (N)

Department of Rheumatology, National Hospital Organization Nagasaki Medical Center, Omura, Japan.

Yasumori Izumi (Y)

Department of General Internal Medicine, National Hospital Organization Nagasaki Medical Center, Omura, Japan.

Yuki Matsuoka (Y)

Department of Pathology, National Hospital Organization Nagasaki Medical Center, Nagasaki, Japan.

Shiro Miura (S)

Department of Pathology, National Hospital Organization Nagasaki Medical Center, Nagasaki, Japan.

Atsushi Kawakami (A)

Division of Advanced Preventive Medical Sciences, Department of Immunology and Rheumatology, Nagasaki University Graduate School of Biomedical Sciences, Nagasaki, Japan.

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