Use of Nevelia Dermal-Epidermal Regenerative Template in the Management of Ischemic Diabetic Foot Postsurgical Wounds.


Journal

The international journal of lower extremity wounds
ISSN: 1552-6941
Titre abrégé: Int J Low Extrem Wounds
Pays: United States
ID NLM: 101128359

Informations de publication

Date de publication:
Sep 2020
Historique:
pubmed: 31 1 2020
medline: 29 6 2021
entrez: 31 1 2020
Statut: ppublish

Résumé

The purpose of this cross-sectional study is evaluate the effectiveness of a dermal-epidermal substitute (DES) composed of 3-dimensional porous matrix of type 1, purified, stabilized, bovin-origin collagen (Nevelia, SYMATESE, Chaponost, France) without a subsequent skin graft in the treatment ischemic postsurgical diabetic foot ulcers. This study group was composed of a sample of consecutive diabetic patients with critical limb ischemia and postsurgical wounds. All patients received a preset limb salvage protocol including the application of the DES, but none received a skin graft. Patients were closely followed until wound healing or different outcome. The outcome measures were healing, nonhealing, major amputation, and death evaluated at 1 and 2 years of follow-up. Forty-one patients were included. The average postsurgical wound area was 69.6 ± 50 cm

Identifiants

pubmed: 31996064
doi: 10.1177/1534734619896460
doi:

Types de publication

Journal Article

Langues

eng

Sous-ensembles de citation

IM

Pagination

282-288

Auteurs

Luigi Uccioli (L)

University of Tor Vergata, Rome, Italy.

Marco Meloni (M)

University of Tor Vergata, Rome, Italy.

Valentina Izzo (V)

University of Tor Vergata, Rome, Italy.

Laura Giurato (L)

University of Tor Vergata, Rome, Italy.

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Classifications MeSH