Pregnancy outcomes in women with idiopathic inflammatory myopathy, before and after diagnosis-a population-based study.
Adult
Cesarean Section
/ statistics & numerical data
Female
Humans
Infant, Low Birth Weight
Infant, Newborn
Myositis
/ diagnosis
Pregnancy
Pregnancy Complications
/ diagnosis
Pregnancy Outcome
/ epidemiology
Premature Birth
/ epidemiology
Prognosis
Registries
/ statistics & numerical data
Risk Assessment
/ methods
Sweden
/ epidemiology
adverse pregnancy outcomes
caesarean section
idiopathic inflammatory myopathy
low birth weight
preterm birth
Journal
Rheumatology (Oxford, England)
ISSN: 1462-0332
Titre abrégé: Rheumatology (Oxford)
Pays: England
ID NLM: 100883501
Informations de publication
Date de publication:
01 09 2020
01 09 2020
Historique:
received:
10
09
2019
revised:
11
12
2019
pubmed:
31
1
2020
medline:
26
1
2021
entrez:
31
1
2020
Statut:
ppublish
Résumé
To examine pregnancy outcomes among births to women with idiopathic inflammatory myopathy (IIM) in relation to time of IIM diagnosis using population-based data. This study used Swedish nationwide registers to identify all singleton births that occurred between 1973 and 2016 among women diagnosed with IIM between 1998 and 2016 and among women unexposed to IIM. We classified births according to the IIM status of the mother at time of delivery: post-IIM (n = 68), 1-3 years pre-IIM (n = 23), >3 years pre-IIM (n = 710) and unexposed to IIM (n = 4101). Multivariate regression models were used to estimate relative risks of adverse pregnancy outcomes in post-IIM births and pre-IIM births separately, in comparison with their non-IIM comparators. We found that post-IIM births had increased risks of caesarean section [adjusted relative risk (aRR) = 1.98; 95% CI: 1.08, 3.64], preterm birth (aRR = 3.35; 95% CI: 1.28, 8.73) and low birth weight (aRR = 5.69; 95% CI: 1.84, 17.55) compared with non-IIM comparators. We also noticed higher frequencies of caesarean section and instrumental delivery in 1-3 years pre-IIM births than in the non-IIM comparators. Women who gave birth after IIM diagnosis had higher risks of caesarean section, preterm birth and low birth weight. These results further underline the importance of special care and close monitoring of women with IIM. Higher frequencies of caesarean section and instrumental delivery in pre-IIM births highlight the need for future research on the influence of subclinical features of IIM on pregnancy outcomes.
Identifiants
pubmed: 31998957
pii: 5717945
doi: 10.1093/rheumatology/kez666
pmc: PMC7449806
doi:
Types de publication
Journal Article
Research Support, Non-U.S. Gov't
Langues
eng
Sous-ensembles de citation
IM
Pagination
2572-2580Informations de copyright
© The Author(s) 2020. Published by Oxford University Press on behalf of the British Society for Rheumatology.
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