Efficacy of crystal violet for identifying the distal end in esophageal submucosal tunnel resection.


Journal

Minimally invasive therapy & allied technologies : MITAT : official journal of the Society for Minimally Invasive Therapy
ISSN: 1365-2931
Titre abrégé: Minim Invasive Ther Allied Technol
Pays: England
ID NLM: 9612996

Informations de publication

Date de publication:
Jun 2021
Historique:
pubmed: 1 2 2020
medline: 22 6 2021
entrez: 1 2 2020
Statut: ppublish

Résumé

Endoscopic submucosal tunnel dissection (ESTD) has recently been an effective procedure for resecting large early esophageal neoplasm. However, excessive dissection beyond the distal limit may occur because the prepared distal end often cannot be distinguished through the tunnel. This study aimed to assess the efficacy and safety of a novel crystal violet navigation (CVN) for identifying the distal end. In the observational case series study, all 22 patients who underwent esophageal ESTD using the CVN were included. When setting the distal end, the distal incision line was dyed purple using a crystal violet solution. The rates of purple color identified The rates of purple color and successful tunnel penetration were both 100%. En bloc and curative resection were 100%, and 86%, respectively. The mean total procedure time was 103.9 ± 46.2 (mean ± SD) minutes, while the mean time for the CVN was 14.1 ± 3.44 s. No complications were observed. The simple CVN method can be a navigation tool for identifying the distal end during the ESTD procedure.

Sections du résumé

BACKGROUND BACKGROUND
Endoscopic submucosal tunnel dissection (ESTD) has recently been an effective procedure for resecting large early esophageal neoplasm. However, excessive dissection beyond the distal limit may occur because the prepared distal end often cannot be distinguished through the tunnel. This study aimed to assess the efficacy and safety of a novel crystal violet navigation (CVN) for identifying the distal end.
MATERIAL AND METHODS METHODS
In the observational case series study, all 22 patients who underwent esophageal ESTD using the CVN were included. When setting the distal end, the distal incision line was dyed purple using a crystal violet solution. The rates of purple color identified
RESULTS RESULTS
The rates of purple color and successful tunnel penetration were both 100%. En bloc and curative resection were 100%, and 86%, respectively. The mean total procedure time was 103.9 ± 46.2 (mean ± SD) minutes, while the mean time for the CVN was 14.1 ± 3.44 s. No complications were observed.
CONCLUSIONS CONCLUSIONS
The simple CVN method can be a navigation tool for identifying the distal end during the ESTD procedure.

Identifiants

pubmed: 32003276
doi: 10.1080/13645706.2020.1720252
doi:

Substances chimiques

Gentian Violet J4Z741D6O5

Types de publication

Journal Article

Langues

eng

Sous-ensembles de citation

IM

Pagination

133-138

Auteurs

Hideki Kobara (H)

Department of Gastroenterology and Neurology, Faculty of Medicine, Kagawa University, Kagawa, Japan.

Noriko Nishiyama (N)

Department of Gastroenterology and Neurology, Faculty of Medicine, Kagawa University, Kagawa, Japan.

Hirohito Mori (H)

Department of Gastroenterology and Neurology, Faculty of Medicine, Kagawa University, Kagawa, Japan.

Shintaro Fujihara (S)

Department of Gastroenterology and Neurology, Faculty of Medicine, Kagawa University, Kagawa, Japan.

Tingting Shi (T)

Department of Gastroenterology and Neurology, Faculty of Medicine, Kagawa University, Kagawa, Japan.

Kazuhiro Kozuka (K)

Department of Gastroenterology and Neurology, Faculty of Medicine, Kagawa University, Kagawa, Japan.

Taiga Chiyo (T)

Department of Gastroenterology and Neurology, Faculty of Medicine, Kagawa University, Kagawa, Japan.

Nobuya Kobayashi (N)

Department of Gastroenterology and Neurology, Faculty of Medicine, Kagawa University, Kagawa, Japan.

Koji Fujita (K)

Department of Gastroenterology and Neurology, Faculty of Medicine, Kagawa University, Kagawa, Japan.

Joji Tani (J)

Department of Gastroenterology and Neurology, Faculty of Medicine, Kagawa University, Kagawa, Japan.

Tatsuo Yachida (T)

Department of Gastroenterology and Neurology, Faculty of Medicine, Kagawa University, Kagawa, Japan.

Kunihiko Tsutsui (K)

Department of Gastroenterology and Neurology, Faculty of Medicine, Kagawa University, Kagawa, Japan.

Keiichi Okano (K)

Department of Gastroenterological Surgery, Faculty of Medicine, Kagawa University, Kagawa, Japan.

Yasuyuki Suzuki (Y)

Department of Gastroenterological Surgery, Faculty of Medicine, Kagawa University, Kagawa, Japan.

Tsutomu Masaki (T)

Department of Gastroenterology and Neurology, Faculty of Medicine, Kagawa University, Kagawa, Japan.

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Classifications MeSH