Red cell use in trauma.


Journal

Current opinion in anaesthesiology
ISSN: 1473-6500
Titre abrégé: Curr Opin Anaesthesiol
Pays: United States
ID NLM: 8813436

Informations de publication

Date de publication:
Apr 2020
Historique:
pubmed: 1 2 2020
medline: 11 3 2020
entrez: 1 2 2020
Statut: ppublish

Résumé

Red cell transfusions are commonly used in management of hemorrhage in trauma patients. The appropriate indications and criteria for transfusion are still debated. Here, we summarize the recent findings on the use of red cell transfusion in trauma setting. Recent evidence continues to support the long-established link between allogeneic transfusion and worse clinical outcomes, reinstating the importance of more judicious use of allogeneic blood and careful consideration of benefits versus risks when making transfusion decisions. Studies support restrictive transfusion strategies (often based on hemoglobin thresholds of 7-8 g/dl) in most patient populations, although some argue more caution in specific populations (e.g. patients with traumatic brain injury) and more studies are needed to determine if these patients benefit from less restrictive transfusion strategies. It should be remembered that anemia remains an independent risk factor for worse outcomes and red cell transfusion does not constitute a lasting treatment. Anemia should be properly assessed and managed based on the cause and using hematinic medications as indicated. Although the debate on hemoglobin thresholds for transfusion continues, clinicians should not overlook proper management of the underlying issue (anemia).

Identifiants

pubmed: 32004168
doi: 10.1097/ACO.0000000000000837
pii: 00001503-202004000-00016
doi:

Substances chimiques

Hemoglobins 0

Types de publication

Journal Article Review

Langues

eng

Sous-ensembles de citation

IM

Pagination

220-226

Références

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Auteurs

Aryeh Shander (A)

Department of Anesthesiology and Critical Care Medicine; Englewood Hospital and Medical Center.
TeamHealth Research Institute; Englewood.
Icahn School Of Medicine at Mount Sinai, New York, NY, USA.

Kai Zacharowski (K)

Department of Anesthesiology, Intensive Care Medicine & Pain Therapy, University Hospital Frankfurt, Goethe University, Frankfurt, Main, Germany.

Donat R Spahn (DR)

Institute of Anesthesiology, University and University Hospital Zürich, Zürich, Switzerland.

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