Predictive accuracy and clinical benefit of a nomogram aimed to predict


Journal

European journal of nuclear medicine and molecular imaging
ISSN: 1619-7089
Titre abrégé: Eur J Nucl Med Mol Imaging
Pays: Germany
ID NLM: 101140988

Informations de publication

Date de publication:
08 2020
Historique:
received: 24 10 2019
accepted: 12 01 2020
pubmed: 2 2 2020
medline: 15 5 2021
entrez: 2 2 2020
Statut: ppublish

Résumé

To perform an external validation of a recently published nomogram aimed to predict positive Overall, 413 PCa patients with BCR after RP (two consecutive PSA ≥ 0.2 ng/ml) and PSA value between 0.2 and 1 ng/ml were included. A multivariable logistic regression model was produced to assess the predictors of positive In the external cohort, the overall detection rate of We assessed similar suboptimal predictive accuracies in the external cohort compared to the original one. PSA and ongoing ADT were confirmed as positive predictors, and the most informative nomogram cut-off resulted 35%.

Identifiants

pubmed: 32006061
doi: 10.1007/s00259-020-04696-z
pii: 10.1007/s00259-020-04696-z
doi:

Substances chimiques

Gallium Isotopes 0
Gallium Radioisotopes 0
Oligopeptides 0
gallium 68 PSMA-11 0
Edetic Acid 9G34HU7RV0
Prostate-Specific Antigen EC 3.4.21.77

Types de publication

Journal Article

Langues

eng

Sous-ensembles de citation

IM

Pagination

2100-2105

Auteurs

Lorenzo Bianchi (L)

Department of Urology, University of Bologna, S. Orsola-Malpighi Hospital, Via Palagi 9, 40138, Bologna, Italy. lorenzo.bianchi3@gmail.com.
Department of Specialistic, Diagnostic and Experimental Medicine (DIMES), University of Bologna, Bologna, Italy. lorenzo.bianchi3@gmail.com.

Marco Borghesi (M)

Department of Urology, University of Bologna, S. Orsola-Malpighi Hospital, Via Palagi 9, 40138, Bologna, Italy.
Department of Specialistic, Diagnostic and Experimental Medicine (DIMES), University of Bologna, Bologna, Italy.

Riccardo Schiavina (R)

Department of Urology, University of Bologna, S. Orsola-Malpighi Hospital, Via Palagi 9, 40138, Bologna, Italy.
Department of Specialistic, Diagnostic and Experimental Medicine (DIMES), University of Bologna, Bologna, Italy.

Paolo Castellucci (P)

Metropolitan Nuclear Medicine, S. Orsola-Malpighi University Hospital, University of Bologna, Bologna, Italy.

Amelio Ercolino (A)

Department of Urology, University of Bologna, S. Orsola-Malpighi Hospital, Via Palagi 9, 40138, Bologna, Italy.

Federico Mineo Bianchi (FM)

Department of Urology, University of Bologna, S. Orsola-Malpighi Hospital, Via Palagi 9, 40138, Bologna, Italy.

Umberto Barbaresi (U)

Department of Urology, University of Bologna, S. Orsola-Malpighi Hospital, Via Palagi 9, 40138, Bologna, Italy.

Giulia Polverari (G)

Metropolitan Nuclear Medicine, S. Orsola-Malpighi University Hospital, University of Bologna, Bologna, Italy.
Nuclear Medicine, Department of Medical Sciences, University of Turin, Turin, Italy.

Eugenio Brunocilla (E)

Department of Urology, University of Bologna, S. Orsola-Malpighi Hospital, Via Palagi 9, 40138, Bologna, Italy.
Department of Specialistic, Diagnostic and Experimental Medicine (DIMES), University of Bologna, Bologna, Italy.

Stefano Fanti (S)

Metropolitan Nuclear Medicine, S. Orsola-Malpighi University Hospital, University of Bologna, Bologna, Italy.

Francesco Ceci (F)

Department of Specialistic, Diagnostic and Experimental Medicine (DIMES), University of Bologna, Bologna, Italy.
Nuclear Medicine, Department of Medical Sciences, University of Turin, Turin, Italy.

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Classifications MeSH