Hair cortisol levels in posttraumatic stress disorder and metabolic syndrome.
Posttraumatic stress disorder
cardiovascular disease
hair cortisol concentrations
hypothalamic–pituitary–adrenal (HPA) axis
metabolic syndrome
trauma
Journal
Stress (Amsterdam, Netherlands)
ISSN: 1607-8888
Titre abrégé: Stress
Pays: England
ID NLM: 9617529
Informations de publication
Date de publication:
09 2020
09 2020
Historique:
pubmed:
6
2
2020
medline:
25
3
2021
entrez:
4
2
2020
Statut:
ppublish
Résumé
Individuals with post-traumatic stress disorder (PTSD) evidence increased rates of metabolic syndrome (MetS), and both PTSD and MetS are associated with alterations in hypothalamic-pituitary-adrenal (HPA) axis function. Few investigations have examined the possible role of HPA-axis dysfunction in the co-occurrence of PTSD and MetS. In a case-control study, we aimed to determine whether hair cortisol concentrations (HCC) were associated with (i) PTSD caseness and severity and (ii) PTSD and MetS co-occurrence. We used the Clinician-Administered PTSD Scale for DSM-5 (CAPS-5) to determine PTSD diagnoses and severity scores in 216 females of mixed ancestry aged between 20 and 79 years (
Identifiants
pubmed: 32008379
doi: 10.1080/10253890.2020.1724949
doi:
Substances chimiques
Hydrocortisone
WI4X0X7BPJ
Types de publication
Journal Article
Research Support, Non-U.S. Gov't
Langues
eng
Sous-ensembles de citation
IM