The Placental Basis of Fetal Growth Restriction.
Fetal growth restriction (FGR)
Fetal vascular malperfusion (FVM)
Intrauterine growth restriction (IUGR)
Maternal vascular malperfusion (MVM)
Placental dysfunction
Placental growth factor (PlGF)
Placental insufficiency
Placental pathology
Journal
Obstetrics and gynecology clinics of North America
ISSN: 1558-0474
Titre abrégé: Obstet Gynecol Clin North Am
Pays: United States
ID NLM: 8709551
Informations de publication
Date de publication:
Mar 2020
Mar 2020
Historique:
entrez:
4
2
2020
pubmed:
6
2
2020
medline:
12
11
2020
Statut:
ppublish
Résumé
Placental dysfunction is a major contributing factor to fetal growth restriction. Placenta-mediated fetal growth restriction occurs through chronic fetal hypoxia owing to poor placental perfusion through a variety of mechanisms. Maternal vascular malperfusion is the most common placental disease contributing to fetal growth restriction; however, the role of rare placental diseases should not be overlooked. Although the features of maternal vascular malperfusion are identifiable on placental pathology, antepartum diagnostic methods are evolving. Placental imaging and uterine artery Doppler, used in conjunction with angiogenic growth factors (specifically placenta growth factor and soluble fms-like tyrosine kinase-1), play an increasingly important role.
Identifiants
pubmed: 32008673
pii: S0889-8545(19)30118-4
doi: 10.1016/j.ogc.2019.10.008
pii:
doi:
Types de publication
Journal Article
Review
Langues
eng
Sous-ensembles de citation
IM
Pagination
81-98Informations de copyright
Copyright © 2019 Elsevier Inc. All rights reserved.