Insight the Biological Activities of Selected Abietane Diterpenes Isolated from
Abietanes
/ pharmacology
Antineoplastic Agents, Phytogenic
/ pharmacology
Apoptosis
Brain Neoplasms
/ drug therapy
Cell Cycle
Cell Line, Tumor
Cell Survival
DNA Breaks, Double-Stranded
Drug Design
Flow Cytometry
Glioma
/ drug therapy
Histones
/ chemistry
Humans
Membrane Potential, Mitochondrial
/ drug effects
Necrosis
Phosphorylation
Plant Extracts
/ pharmacology
Plectranthus
/ chemistry
H2A.X
apoptosis
cell cycle
cytotoxic activity
gene expression
mitochondrial membrane potential
natural abietane diterpenes
Journal
Biomolecules
ISSN: 2218-273X
Titre abrégé: Biomolecules
Pays: Switzerland
ID NLM: 101596414
Informations de publication
Date de publication:
28 01 2020
28 01 2020
Historique:
received:
28
12
2019
revised:
20
01
2020
accepted:
22
01
2020
entrez:
5
2
2020
pubmed:
6
2
2020
medline:
30
3
2021
Statut:
epublish
Résumé
Natural compounds isolated from plants are excellent starting points in drug design and have been widely studied as anticancer agents; they hence find use in a considerable proportion of anticancer drugs. The genus
Identifiants
pubmed: 32012853
pii: biom10020194
doi: 10.3390/biom10020194
pmc: PMC7072155
pii:
doi:
Substances chimiques
2-(4-hydroxy)-benzoyloxy-11-hydroxy-5,7,9(11),13-abietatetraen-12-one
0
Abietanes
0
Antineoplastic Agents, Phytogenic
0
Histones
0
Plant Extracts
0
Types de publication
Journal Article
Langues
eng
Sous-ensembles de citation
IM
Déclaration de conflit d'intérêts
The authors declare no conflict of interest.
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