Synthesis and Bioactivity of Phthalimide Analogs as Potential Drugs to Treat Schistosomiasis, a Neglected Disease of Poverty.

Schistosoma anti-schistosomal activity benzimidazole click chemistry drug discovery phthalimide tropical disease

Journal

Pharmaceuticals (Basel, Switzerland)
ISSN: 1424-8247
Titre abrégé: Pharmaceuticals (Basel)
Pays: Switzerland
ID NLM: 101238453

Informations de publication

Date de publication:
03 02 2020
Historique:
received: 24 12 2019
revised: 16 01 2020
accepted: 17 01 2020
entrez: 8 2 2020
pubmed: 8 2 2020
medline: 8 2 2020
Statut: epublish

Résumé

The neglected tropical disease, schistosomiasis, is caused by trematode blood flukes of the

Identifiants

pubmed: 32028743
pii: ph13020025
doi: 10.3390/ph13020025
pmc: PMC7169845
pii:
doi:

Types de publication

Journal Article

Langues

eng

Déclaration de conflit d'intérêts

The authors declare no competing financial interest.

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Auteurs

Snigdha Singh (S)

Laboratory for Translational Chemistry and Drug Discovery, Department of Chemistry, Hansraj College, University of Delhi, Delhi 110007, India.

Nelly El-Sakkary (N)

Center for Discovery and Innovation in Parasitic Diseases, Skaggs School of Pharmacy and Pharmaceutical Sciences, University of California San Diego, 9500 Gilman Drive, La Jolla, CA 92093, USA.

Danielle E Skinner (DE)

Center for Discovery and Innovation in Parasitic Diseases, Skaggs School of Pharmacy and Pharmaceutical Sciences, University of California San Diego, 9500 Gilman Drive, La Jolla, CA 92093, USA.

Prem Prakash Sharma (PP)

Laboratory for Translational Chemistry and Drug Discovery, Department of Chemistry, Hansraj College, University of Delhi, Delhi 110007, India.

Sabine Ottilie (S)

Department of Pediatrics, University of California, San Diego, School of Medicine, La Jolla, CA 92093, USA.

Yevgeniya Antonova-Koch (Y)

Department of Pediatrics, University of California, San Diego, School of Medicine, La Jolla, CA 92093, USA.

Prashant Kumar (P)

Department of Chemistry, SRM University, Delhi-NCR, Sonepat, Haryana 131029, India.

Elizabeth Winzeler (E)

Department of Pediatrics, University of California, San Diego, School of Medicine, La Jolla, CA 92093, USA.
Department of Chemistry, Miranda House, University of Delhi, Delhi 110007, India.

Conor R Caffrey (CR)

Center for Discovery and Innovation in Parasitic Diseases, Skaggs School of Pharmacy and Pharmaceutical Sciences, University of California San Diego, 9500 Gilman Drive, La Jolla, CA 92093, USA.

Brijesh Rathi (B)

Laboratory for Translational Chemistry and Drug Discovery, Department of Chemistry, Hansraj College, University of Delhi, Delhi 110007, India.

Classifications MeSH