Conor R Caffrey

Affiliations

Center for Discovery and Innovation in Parasitic Diseases, Skaggs School of Pharmacy and Pharmaceutical Sciences, University of California, San Diego, La Jolla, CA, United States of America.

Publications (16)

Evaluation of a class of isatinoids identified from a high-throughput screen of human kinase inhibitors as anti-Sleeping Sickness agents.

PLoS neglected tropical diseases

Avec: Dana M Klug , Rosario Diaz-Gonzalez , Guiomar Pérez-Moreno , Gloria Ceballos-Pérez , Raquel García-Hernández , Veronica Gomez-Pérez , Luis Miguel Ruiz-Pérez , Domingo I Rojas-Barros , Francisco Gamarro , Dolores González-Pacanowska , María S Martínez-Martínez , Pilar Manzano , Lori Ferrins , Conor R Caffrey , Miguel Navarro , Michael P Pollastri

Uncovering Biological Application of Brazilian Green Propolis: A Phenotypic Screening against Schistosoma mansoni.

Chemistry & biodiversity

Avec: Lucas A de L Paula , Mario F C Santos , Mariana C Pagotti , Renata Faleiros , Henrique P Ramos , Rodrigo C S Veneziani , Jairo K Bastos , Conor R Caffrey , Sérgio R Ambrosio , Lizandra G Magalhães

Efficacy, metabolism and pharmacokinetics of Ro 15-5458, a forgotten schistosomicidal 9-acridanone hydrazone.

The Journal of antimicrobial chemotherapy

Avec: Alexandra Probst , Cécile Häberli , Dionicio Siegel , Jianbo Huang , Seth Vigneron , Anh P Ta , Danielle E Skinner , Nelly El-Sakkary , Jeremiah D Momper , Jon Gangoiti , Yuxiang Dong , Jonathan L Vennerstrom , Susan A Charman , Conor R Caffrey , Jennifer Keiser

Anti-schistosomal activities of quinoxaline-containing compounds: From hit identification to lead optimisation.

European journal of medicinal chemistry

Avec: Gilda Padalino , Nelly El-Sakkary , Lawrence J Liu , Chenxi Liu , Danielle S G Harte , Rachel E Barnes , Edward Sayers , Josephine Forde-Thomas , Helen Whiteland , Marcella Bassetto , Salvatore Ferla , George Johnson , Arwyn T Jones , Conor R Caffrey , Iain Chalmers , Andrea Brancale , Karl F Hoffmann

Structure-Based Optimization of Quinazolines as Cruzain and

Journal of medicinal chemistry

Avec: Elany Barbosa da Silva , Débora A Rocha , Isadora S Fortes , Wenqian Yang , Ludovica Monti , Jair L Siqueira-Neto , Conor R Caffrey , James McKerrow , Saulo F Andrade , Rafaela S Ferreira

Antiparasitic Properties of Propolis Extracts and Their Compounds.

Chemistry & biodiversity

Avec: Lucas A de L Paula , Ana C B B Cândido , Mario F C Santos , Conor R Caffrey , Jairo K Bastos , Sérgio R Ambrósio , Lizandra G Magalhães

Development of subunit selective substrates for

bioRxiv : the preprint server for biology

Avec: Pavla Fajtova , Brianna M Hurysz , Yukiko Miyamoto , Mateus Serafim , Zhenze Jiang , Diego F Trujillo , Lawrence Liu , Urvashi Somani , Jehad Almaliti , Samuel A Myers , Conor R Caffrey , William H Gerwick , Christopher J Kirk , Evzen Boura , Lars Eckmann , Anthony J O'Donoghue

Biomechanics of parasite migration within hosts.

Trends in parasitology

Avec: Yi-Ting Yeh , Juan C Del Álamo , Conor R Caffrey

EF24, a schistosomicidal curcumin analog: Insights from its synthesis and phenotypic, biochemical and cytotoxic activities.

Chemico-biological interactions

Avec: Fernanda R Badoco , Lucas A L Paula , Renato P Orenha , Tiago M F Mendes , Iara S Squarisi , Nelly El-Sakkary , Messias C Loiola , Naftale Katz , Denise C Tavares , Mirela I Sairre , Renato Luis T Parreira , Fernanda Janku Cabral , Silmara M Alegretti , Conor R Caffrey , Lizandra G Magalhães

Structure-activity relationship of dibenzylideneacetone analogs against the neglected disease pathogen, Trypanosoma brucei.

Bioorganic & medicinal chemistry letters

Avec: Karol R Francisco , Ludovica Monti , Wenqian Yang , Hayoung Park , Lawrence J Liu , Kaitlyn Watkins , Dilini K Amarasinghe , Marianna Nalli , Carlos Roberto Polaquini , Luis O Regasini , Antônio Eduardo Miller Crotti , Romano Silvestri , Lizandra Guidi Magalhães , Conor R Caffrey

Structure-Activity Relationships, Tolerability and Efficacy of Microtubule-Active 1,2,4-Triazolo[1,5-

bioRxiv : the preprint server for biology

Avec: Ludovica Monti , Lawrence J Liu , Carmine Varricchio , Bobby Lucero , Thibault Alle , Wenqian Yang , Ido Bem-Shalom , Michael Gilson , Kurt R Brunden , Andrea Brancale , Conor R Caffrey , Carlo Ballatore

Protein-protein interactions: developing small-molecule inhibitors/stabilizers through covalent strategies.

Trends in pharmacological sciences

Avec: Bobby Lucero , Karol R Francisco , Lawrence J Liu , Conor R Caffrey , Carlo Ballatore

Author Correction: Caenorhabditis elegans is a useful model for anthelmintic discovery.

Nature communications

Avec: Andrew R Burns , Genna M Luciani , Gabriel Musso , Rachel Bagg , May Yeo , Yuqian Zhang , Luckshi Rajendran , John Glavin , Robert Hunter , Elizabeth Redman , Susan Stasiuk , Michael Schertzberg , G Angus McQuibban , Conor R Caffrey , Sean R Cutler , Mike Tyers , Guri Giaever , Corey Nislow , Andy G Fraser , Calum A MacRae , John Gilleard , Peter J Roy

Selectivity and Physicochemical Optimization of Repurposed Pyrazolo[1,5-

Journal of medicinal chemistry

Avec: Westley F Tear , Seema Bag , Rosario Diaz-Gonzalez , Gloria Ceballos-Pérez , Domingo I Rojas-Barros , Carlos Cordon-Obras , Guiomar Pérez-Moreno , Raquel García-Hernández , Maria Santos Martinez-Martinez , Luis Miguel Ruiz-Perez , Francisco Gamarro , Dolores Gonzalez Pacanowska , Conor R Caffrey , Lori Ferrins , Pilar Manzano , Miguel Navarro , Michael P Pollastri

Quantifying the mechanics of locomotion of the schistosome pathogen with respect to changes in its physical environment.

Journal of the Royal Society, Interface

Avec: Shun Zhang , Danielle Skinner , Prateek Joshi , Ernesto Criado-Hidalgo , Yi-Ting Yeh , Juan C Lasheras , Conor R Caffrey , Juan C Del Alamo

Bioactivity of Farnesyltransferase Inhibitors Against

Frontiers in cellular and infection microbiology

Avec: Alexandra Probst , Thi N Nguyen , Nelly El-Sakkary , Danielle Skinner , Brian M Suzuki , Frederick S Buckner , Michael H Gelb , Conor R Caffrey , Anjan Debnath

Réseau de co-auteurs

Nelly El-Sakkary 4 collaborations

Lawrence J Liu 4 collaborations

Lizandra G Magalhães 3 collaborations

Wenqian Yang 3 collaborations

Ludovica Monti 3 collaborations

Rosario Diaz-Gonzalez 2 collaborations

Guiomar Pérez-Moreno 2 collaborations

Gloria Ceballos-Pérez 2 collaborations

Raquel García-Hernández 2 collaborations

Domingo I Rojas-Barros 2 collaborations

Francisco Gamarro 2 collaborations

Pilar Manzano 2 collaborations

Lori Ferrins 2 collaborations

Miguel Navarro 2 collaborations

Michael P Pollastri 2 collaborations

Lucas A de L Paula 2 collaborations

Mario F C Santos 2 collaborations

Jairo K Bastos 2 collaborations

Alexandra Probst 2 collaborations

Andrea Brancale 2 collaborations

Yi-Ting Yeh 2 collaborations

Karol R Francisco 2 collaborations

Bobby Lucero 2 collaborations

Carlo Ballatore 2 collaborations

Danielle Skinner 2 collaborations

Dana M Klug 1 collaboration

Veronica Gomez-Pérez 1 collaboration

Luis Miguel Ruiz-Pérez 1 collaboration

Dolores González-Pacanowska 1 collaboration

María S Martínez-Martínez 1 collaboration

Mariana C Pagotti 1 collaboration

Renata Faleiros 1 collaboration

Henrique P Ramos 1 collaboration

Rodrigo C S Veneziani 1 collaboration

Sérgio R Ambrosio 1 collaboration

Cécile Häberli 1 collaboration

Dionicio Siegel 1 collaboration

Jianbo Huang 1 collaboration

Seth Vigneron 1 collaboration

Anh P Ta 1 collaboration

Danielle E Skinner 1 collaboration

Jeremiah D Momper 1 collaboration

Jon Gangoiti 1 collaboration

Yuxiang Dong 1 collaboration

Jonathan L Vennerstrom 1 collaboration

Susan A Charman 1 collaboration

Jennifer Keiser 1 collaboration

Gilda Padalino 1 collaboration

Chenxi Liu 1 collaboration

Danielle S G Harte 1 collaboration

Rachel E Barnes 1 collaboration

Edward Sayers 1 collaboration

Josephine Forde-Thomas 1 collaboration

Helen Whiteland 1 collaboration

Marcella Bassetto 1 collaboration

Salvatore Ferla 1 collaboration

George Johnson 1 collaboration

Arwyn T Jones 1 collaboration

Iain Chalmers 1 collaboration

Karl F Hoffmann 1 collaboration

Elany Barbosa da Silva 1 collaboration

Débora A Rocha 1 collaboration

Isadora S Fortes 1 collaboration

Jair L Siqueira-Neto 1 collaboration

James McKerrow 1 collaboration

Saulo F Andrade 1 collaboration

Rafaela S Ferreira 1 collaboration

Ana C B B Cândido 1 collaboration

Sérgio R Ambrósio 1 collaboration

Pavla Fajtova 1 collaboration

Brianna M Hurysz 1 collaboration

Yukiko Miyamoto 1 collaboration

Mateus Serafim 1 collaboration

Zhenze Jiang 1 collaboration

Diego F Trujillo 1 collaboration

Lawrence Liu 1 collaboration

Urvashi Somani 1 collaboration

Jehad Almaliti 1 collaboration

Samuel A Myers 1 collaboration

William H Gerwick 1 collaboration

Christopher J Kirk 1 collaboration

Evzen Boura 1 collaboration

Lars Eckmann 1 collaboration

Anthony J O'Donoghue 1 collaboration

Juan C Del Álamo 1 collaboration

Fernanda R Badoco 1 collaboration

Lucas A L Paula 1 collaboration

Renato P Orenha 1 collaboration

Tiago M F Mendes 1 collaboration

Iara S Squarisi 1 collaboration

Messias C Loiola 1 collaboration

Naftale Katz 1 collaboration

Denise C Tavares 1 collaboration

Mirela I Sairre 1 collaboration

Renato Luis T Parreira 1 collaboration

Fernanda Janku Cabral 1 collaboration

Silmara M Alegretti 1 collaboration

Hayoung Park 1 collaboration

Kaitlyn Watkins 1 collaboration

Dilini K Amarasinghe 1 collaboration

Marianna Nalli 1 collaboration

Carlos Roberto Polaquini 1 collaboration

Luis O Regasini 1 collaboration

Antônio Eduardo Miller Crotti 1 collaboration

Romano Silvestri 1 collaboration

Lizandra Guidi Magalhães 1 collaboration

Carmine Varricchio 1 collaboration

Thibault Alle 1 collaboration

Ido Bem-Shalom 1 collaboration

Michael Gilson 1 collaboration

Kurt R Brunden 1 collaboration

Andrew R Burns 1 collaboration

Genna M Luciani 1 collaboration

Gabriel Musso 1 collaboration

Rachel Bagg 1 collaboration

May Yeo 1 collaboration

Yuqian Zhang 1 collaboration

Luckshi Rajendran 1 collaboration

John Glavin 1 collaboration

Robert Hunter 1 collaboration

Elizabeth Redman 1 collaboration

Susan Stasiuk 1 collaboration

Michael Schertzberg 1 collaboration

G Angus McQuibban 1 collaboration

Sean R Cutler 1 collaboration

Mike Tyers 1 collaboration

Guri Giaever 1 collaboration

Corey Nislow 1 collaboration

Andy G Fraser 1 collaboration

Calum A MacRae 1 collaboration

John Gilleard 1 collaboration

Peter J Roy 1 collaboration

Westley F Tear 1 collaboration

Seema Bag 1 collaboration

Carlos Cordon-Obras 1 collaboration

Maria Santos Martinez-Martinez 1 collaboration

Luis Miguel Ruiz-Perez 1 collaboration

Dolores Gonzalez Pacanowska 1 collaboration

Shun Zhang 1 collaboration

Prateek Joshi 1 collaboration

Ernesto Criado-Hidalgo 1 collaboration

Juan C Lasheras 1 collaboration

Juan C Del Alamo 1 collaboration

Thi N Nguyen 1 collaboration

Brian M Suzuki 1 collaboration

Frederick S Buckner 1 collaboration

Michael H Gelb 1 collaboration

Anjan Debnath 1 collaboration