Jennifer Keiser

Affiliations

Swiss Tropical and Public Health Institute, Socinstrasse 57, P.O. Box, CH-4002 Basel, Switzerland.
Universität Basel, Petersplatz 1, P.O. Box, CH-4001 Basel, Switzerland.

Publications (28)

Mechanochemical Formation of Racemic Praziquantel Hemihydrate with Improved Biopharmaceutical Properties.

Pharmaceutics

Avec: Debora Zanolla , Dritan Hasa , Mihails Arhangelskis , Gabriela Schneider-Rauber , Michele R Chierotti , Jennifer Keiser , Dario Voinovich , William Jones , Beatrice Perissutti

Evaluation of emodepside in laboratory models of human intestinal nematode and schistosome infections.

Parasites & vectors

Avec: Tanja Karpstein , Valérian Pasche , Cécile Häberli , Ivan Scandale , Anna Neodo , Jennifer Keiser

Activity and pharmacokinetics of a praziquantel crystalline polymorph in the Schistosoma mansoni mouse model.

European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft fur Pharmazeutische Verfahrenstechnik e.V

Avec: Flavio C Lombardo , Beatrice Perissutti , Jennifer Keiser

Novel 1-Methyl-1 H-pyrazole-5-carboxamide Derivatives with Potent Anthelmintic Activity.

Journal of medicinal chemistry

Avec: Thuy G Le , Abhijit Kundu , Atanu Ghoshal , Nghi H Nguyen , Sarah Preston , Yaqing Jiao , Banfeng Ruan , Lian Xue , Fei Huang , Jennifer Keiser , Andreas Hofmann , Bill C H Chang , Jose Garcia-Bustos , Timothy N C Wells , Michael J Palmer , Abdul Jabbar , Robin B Gasser , Jonathan B Baell

Structure-Activity Relationship Studies of Tolfenpyrad Reveal Subnanomolar Inhibitors of Haemonchus contortus Development.

Journal of medicinal chemistry

Assessment of fecal calprotectin and fecal occult blood as point-of-care markers for soil-transmitted helminth attributable intestinal morbidity in a case-control substudy conducted in Côte d'Ivoire, Lao PDR and Pemba Island, Tanzania.

EClinicalMedicine

Avec: Chandni Patel , Ladina Keller , Sophie Welsche , Jan Hattendorf , Somphou Sayasone , Said M Ali , Shaali M Ame , Jean Tenena Coulibaly , Eveline Hürlimann , Jennifer Keiser

Pharmacometric Analysis of Tribendimidine Monotherapy and Combination Therapies To Achieve High Cure Rates in Patients with Hookworm Infections.

Antimicrobial agents and chemotherapy

Avec: Janneke M Brussee , Anna Neodo , Jessica D Schulz , Jean T Coulibaly , Marc Pfister , Jennifer Keiser

Population Pharmacokinetics and Exposure-Response Analysis of Tribendimidine To Improve Treatment for Children with Hookworm Infection.

Antimicrobial agents and chemotherapy

Avec: Janneke M Brussee , Noemi Hiroshige , Anna Neodo , Jean T Coulibaly , Marc Pfister , Jennifer Keiser

Evaluation of Commercially Available Anthelminthics in Laboratory Models of Human Intestinal Nematode Infections.

ACS infectious diseases

Avec: Jennifer Keiser , Cécile Häberli

Activities of Quinoxaline, Nitroquinoxaline, and [1,2,4]Triazolo[4,3-a]quinoxaline Analogs of MMV007204 against Schistosoma mansoni.

Antimicrobial agents and chemotherapy

Avec: Stefan L Debbert , Mikaela J Hintz , Christian J Bell , Kenya R Earl , Grant E Forsythe , Cécile Häberli , Jennifer Keiser

Performance of the Kato-Katz method and real time polymerase chain reaction for the diagnosis of soil-transmitted helminthiasis in the framework of a randomised controlled trial: treatment efficacy and day-to-day variation.

Parasites & vectors

Avec: Ladina Keller , Chandni Patel , Sophie Welsche , Tobias Schindler , Eveline Hürlimann , Jennifer Keiser

Development of Praziquantel sulphonamide derivatives as antischistosomal drugs.

Journal of enzyme inhibition and medicinal chemistry

Avec: Andrea Angeli , Marta Ferraroni , Fabrizio Carta , Cécile Häberli , Jennifer Keiser , Gabriele Costantino , Claudiu T Supuran

Long-term outcomes of ivermectin-albendazole versus albendazole alone against soil-transmitted helminths: Results from randomized controlled trials in Lao PDR and Pemba Island, Tanzania.

PLoS neglected tropical diseases

Avec: Ladina Keller , Sophie Welsche , Chandni Patel , Somphou Sayasone , Said M Ali , Shaali M Ame , Jan Hattendorf , Eveline Hürlimann , Jennifer Keiser

Development of emodepside as a possible adulticidal treatment for human onchocerciasis-The fruit of a successful industrial-academic collaboration.

PLoS pathogens

Avec: Jürgen Krücken , Lindy Holden-Dye , Jennifer Keiser , Roger K Prichard , Simon Townson , Benjamin L Makepeace , Marc P Hübner , Steffen R Hahnel , Ivan Scandale , Achim Harder , Daniel Kulke

Modeling the effect of different drugs and treatment regimen for hookworm on cure and egg reduction rates taking into account diagnostic error.

PLoS neglected tropical diseases

Avec: Carla M Grolimund , Oliver Bärenbold , Jürg Utzinger , Jennifer Keiser , Penelope Vounatsou

Pharmacokinetics of Ascending Doses of Praziquantel in Adults Infected with Opisthorchis felineus in Western Siberia, Russian Federation.

Antimicrobial agents and chemotherapy

Avec: Alexandra Probst , Daniela Hofmann , Olga S Fedorova , Sofia V Mazeina , Tatiana S Sokolova , Ekaterina Golovach , Jennifer Keiser

Improving translational power in antischistosomal drug discovery.

Advances in parasitology

Avec: Alexandra Probst , Stefan Biendl , Jennifer Keiser

Helminth infections: Enabling the World Health Organization Road Map.

International journal for parasitology

Avec: Sabine Specht , Jennifer Keiser

Diagnostic tests for human Schistosoma mansoni and Schistosoma haematobium infection: a systematic review and meta-analysis.

The Lancet. Microbe

Avec: Michel T Vaillant , Fred Philippy , Anouk Neven , Jessica Barré , Dmitry Bulaev , Piero L Olliaro , Jürg Utzinger , Jennifer Keiser , Amadou T Garba

Structure-activity relationship and target investigation of 2-aryl quinolines with nematocidal activity.

International journal for parasitology. Drugs and drug resistance

Avec: Harrison T Shanley , Aya C Taki , Nghi Nguyen , Tao Wang , Joseph J Byrne , Ching-Seng Ang , Michael G Leeming , Shuai Nie , Nicholas Williamson , Yuanting Zheng , Neil D Young , Pasi K Korhonen , Andreas Hofmann , Bill C H Chang , Tim N C Wells , Cécile Häberli , Jennifer Keiser , Abdul Jabbar , Brad E Sleebs , Robin B Gasser

Dual Strategy to Design New Agents Targeting

ACS infectious diseases

Avec: Natalie Fuchs , Robert A Zimmermann , Marvin Schwickert , Annika Gunkel , Collin Zimmer , Mergim Meta , Kevin Schwickert , Jennifer Keiser , Cécile Haeberli , Werner Kiefer , Tanja Schirmeister

Identification of a family of species-selective complex I inhibitors as potential anthelmintics.

Nature communications

Avec: Taylor Davie , Xènia Serrat , Lea Imhof , Jamie Snider , Igor Štagljar , Jennifer Keiser , Hiroyuki Hirano , Nobumoto Watanabe , Hiroyuki Osada , Andrew G Fraser

Correction: Modification and optimization of the FECPAKG2 protocol for the detection and quantification of soil-transmitted helminth eggs in human stool.

PLoS neglected tropical diseases

Avec: Mio Ayana , Johnny Vlaminck , Piet Cools , Shaali Ame , Marco Albonico , Daniel Dana , Jennifer Keiser , Helen Manly , Leonardo F Matoso , Zeleke Mekonnen , Antonio Montresor , Rodrigo Correa-Oliveira , Laura Rinaldi , Somphou Sayasone , Stephen J Sowerby , Lensa Tesfaye , Jozef Vercruysse , Greg Mirams , Bruno Levecke

Drug Combinations Against Soil-Transmitted Helminth Infections.

Advances in parasitology

Avec: Wendelin Moser , Christian Schindler , Jennifer Keiser

Pharmacokinetics of Albendazole, Albendazole Sulfoxide, and Albendazole Sulfone Determined from Plasma, Blood, Dried-Blood Spots, and Mitra Samples of Hookworm-Infected Adolescents.

Antimicrobial agents and chemotherapy

Avec: Jessica D Schulz , Anna Neodo , Jean T Coulibaly , Jennifer Keiser

Early Antischistosomal Leads Identified from in Vitro and in Vivo Screening of the Medicines for Malaria Venture Pathogen Box.

ACS infectious diseases

Avec: Valérian Pasche , Benoît Laleu , Jennifer Keiser

Efficacy and Safety of Albendazole in Hookworm-infected Preschool-aged Children, School-aged Children, and Adults in Côte d'Ivoire: A Phase 2 Randomized, Controlled Dose-finding Trial.

Clinical infectious diseases : an official publication of the Infectious Diseases Society of America

Avec: Chandni Patel , Jean T Coulibaly , Daniela Hofmann , Yves N'Gbesso , Jan Hattendorf , Jennifer Keiser

Efficacy, metabolism and pharmacokinetics of Ro 15-5458, a forgotten schistosomicidal 9-acridanone hydrazone.

The Journal of antimicrobial chemotherapy

Avec: Alexandra Probst , Cécile Häberli , Dionicio Siegel , Jianbo Huang , Seth Vigneron , Anh P Ta , Danielle E Skinner , Nelly El-Sakkary , Jeremiah D Momper , Jon Gangoiti , Yuxiang Dong , Jonathan L Vennerstrom , Susan A Charman , Conor R Caffrey , Jennifer Keiser

Réseau de co-auteurs

Cécile Häberli 6 collaborations

Anna Neodo 4 collaborations

Chandni Patel 4 collaborations

Jean T Coulibaly 4 collaborations

Andreas Hofmann 3 collaborations

Bill C H Chang 3 collaborations

Abdul Jabbar 3 collaborations

Robin B Gasser 3 collaborations

Ladina Keller 3 collaborations

Sophie Welsche 3 collaborations

Jan Hattendorf 3 collaborations

Somphou Sayasone 3 collaborations

Eveline Hürlimann 3 collaborations

Alexandra Probst 3 collaborations

Beatrice Perissutti 2 collaborations

Valérian Pasche 2 collaborations

Ivan Scandale 2 collaborations

Thuy G Le 2 collaborations

Abhijit Kundu 2 collaborations

Atanu Ghoshal 2 collaborations

Nghi H Nguyen 2 collaborations

Sarah Preston 2 collaborations

Yaqing Jiao 2 collaborations

Banfeng Ruan 2 collaborations

Lian Xue 2 collaborations

Fei Huang 2 collaborations

Jose Garcia-Bustos 2 collaborations

Timothy N C Wells 2 collaborations

Michael J Palmer 2 collaborations

Jonathan B Baell 2 collaborations

Said M Ali 2 collaborations

Shaali M Ame 2 collaborations

Janneke M Brussee 2 collaborations

Jessica D Schulz 2 collaborations

Marc Pfister 2 collaborations

Jürg Utzinger 2 collaborations

Daniela Hofmann 2 collaborations

Debora Zanolla 1 collaboration

Dritan Hasa 1 collaboration

Mihails Arhangelskis 1 collaboration

Gabriela Schneider-Rauber 1 collaboration

Michele R Chierotti 1 collaboration

Dario Voinovich 1 collaboration

William Jones 1 collaboration

Tanja Karpstein 1 collaboration

Flavio C Lombardo 1 collaboration

Jean Tenena Coulibaly 1 collaboration

Noemi Hiroshige 1 collaboration

Stefan L Debbert 1 collaboration

Mikaela J Hintz 1 collaboration

Christian J Bell 1 collaboration

Kenya R Earl 1 collaboration

Grant E Forsythe 1 collaboration

Tobias Schindler 1 collaboration

Andrea Angeli 1 collaboration

Marta Ferraroni 1 collaboration

Fabrizio Carta 1 collaboration

Gabriele Costantino 1 collaboration

Claudiu T Supuran 1 collaboration

Jürgen Krücken 1 collaboration

Lindy Holden-Dye 1 collaboration

Roger K Prichard 1 collaboration

Simon Townson 1 collaboration

Benjamin L Makepeace 1 collaboration

Marc P Hübner 1 collaboration

Steffen R Hahnel 1 collaboration

Achim Harder 1 collaboration

Daniel Kulke 1 collaboration

Carla M Grolimund 1 collaboration

Oliver Bärenbold 1 collaboration

Penelope Vounatsou 1 collaboration

Olga S Fedorova 1 collaboration

Sofia V Mazeina 1 collaboration

Tatiana S Sokolova 1 collaboration

Ekaterina Golovach 1 collaboration

Stefan Biendl 1 collaboration

Sabine Specht 1 collaboration

Michel T Vaillant 1 collaboration

Fred Philippy 1 collaboration

Anouk Neven 1 collaboration

Jessica Barré 1 collaboration

Dmitry Bulaev 1 collaboration

Piero L Olliaro 1 collaboration

Amadou T Garba 1 collaboration

Harrison T Shanley 1 collaboration

Aya C Taki 1 collaboration

Nghi Nguyen 1 collaboration

Tao Wang 1 collaboration

Joseph J Byrne 1 collaboration

Ching-Seng Ang 1 collaboration

Michael G Leeming 1 collaboration

Shuai Nie 1 collaboration

Nicholas Williamson 1 collaboration

Yuanting Zheng 1 collaboration

Neil D Young 1 collaboration

Pasi K Korhonen 1 collaboration

Tim N C Wells 1 collaboration

Brad E Sleebs 1 collaboration

Natalie Fuchs 1 collaboration

Robert A Zimmermann 1 collaboration

Marvin Schwickert 1 collaboration

Annika Gunkel 1 collaboration

Collin Zimmer 1 collaboration

Mergim Meta 1 collaboration

Kevin Schwickert 1 collaboration

Cécile Haeberli 1 collaboration

Werner Kiefer 1 collaboration

Tanja Schirmeister 1 collaboration

Taylor Davie 1 collaboration

Xènia Serrat 1 collaboration

Lea Imhof 1 collaboration

Jamie Snider 1 collaboration

Igor Štagljar 1 collaboration

Hiroyuki Hirano 1 collaboration

Nobumoto Watanabe 1 collaboration

Hiroyuki Osada 1 collaboration

Andrew G Fraser 1 collaboration

Mio Ayana 1 collaboration

Johnny Vlaminck 1 collaboration

Piet Cools 1 collaboration

Shaali Ame 1 collaboration

Marco Albonico 1 collaboration

Daniel Dana 1 collaboration

Helen Manly 1 collaboration

Leonardo F Matoso 1 collaboration

Zeleke Mekonnen 1 collaboration

Antonio Montresor 1 collaboration

Rodrigo Correa-Oliveira 1 collaboration

Laura Rinaldi 1 collaboration

Stephen J Sowerby 1 collaboration

Lensa Tesfaye 1 collaboration

Jozef Vercruysse 1 collaboration

Greg Mirams 1 collaboration

Bruno Levecke 1 collaboration

Wendelin Moser 1 collaboration

Christian Schindler 1 collaboration

Benoît Laleu 1 collaboration

Yves N'Gbesso 1 collaboration

Dionicio Siegel 1 collaboration

Jianbo Huang 1 collaboration

Seth Vigneron 1 collaboration

Anh P Ta 1 collaboration

Danielle E Skinner 1 collaboration

Nelly El-Sakkary 1 collaboration

Jeremiah D Momper 1 collaboration

Jon Gangoiti 1 collaboration

Yuxiang Dong 1 collaboration

Jonathan L Vennerstrom 1 collaboration

Susan A Charman 1 collaboration

Conor R Caffrey 1 collaboration