Manganese-enhanced T
Animals
Contrast Media
/ administration & dosage
Disease Models, Animal
Female
Fluorodeoxyglucose F18
/ administration & dosage
Heart
/ diagnostic imaging
Humans
Magnetic Resonance Imaging
Manganese
/ administration & dosage
Myocardial Infarction
/ diagnostic imaging
Myocardium
/ pathology
Positron-Emission Tomography
Rats
Tissue Survival
Ventricular Remodeling
/ physiology
Journal
Scientific reports
ISSN: 2045-2322
Titre abrégé: Sci Rep
Pays: England
ID NLM: 101563288
Informations de publication
Date de publication:
06 02 2020
06 02 2020
Historique:
received:
29
07
2019
accepted:
08
01
2020
entrez:
8
2
2020
pubmed:
8
2
2020
medline:
21
11
2020
Statut:
epublish
Résumé
Gadolinium chelates are widely used in cardiovascular magnetic resonance imaging (MRI) as passive intravascular and extracellular space markers. Manganese, a biologically active paramagnetic calcium analogue, provides novel intracellular myocardial tissue characterisation. We previously showed manganese-enhanced MRI (MEMRI) more accurately quantifies myocardial infarction than gadolinium delayed-enhancement MRI (DEMRI). Here, we evaluated the potential of MEMRI to assess myocardial viability compared to gold-standard
Identifiants
pubmed: 32029765
doi: 10.1038/s41598-020-58716-x
pii: 10.1038/s41598-020-58716-x
pmc: PMC7005182
doi:
Substances chimiques
Contrast Media
0
Fluorodeoxyglucose F18
0Z5B2CJX4D
Manganese
42Z2K6ZL8P
Types de publication
Comparative Study
Journal Article
Research Support, Non-U.S. Gov't
Validation Study
Langues
eng
Sous-ensembles de citation
IM
Pagination
2018Subventions
Organisme : British Heart Foundation
ID : FS/17/19/32641
Pays : United Kingdom
Organisme : British Heart Foundation
ID : RG/16/10/32375
Pays : United Kingdom
Organisme : British Heart Foundation
ID : FS/14/78/31020
Pays : United Kingdom
Organisme : British Heart Foundation
ID : RG/14/3/30706
Pays : United Kingdom
Organisme : Medical Research Council
ID : G0701127
Pays : United Kingdom
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