In Search of Covariates of HIV-1 Subtype B Spread in the United States-A Cautionary Tale of Large-Scale Bayesian Phylogeography.


Journal

Viruses
ISSN: 1999-4915
Titre abrégé: Viruses
Pays: Switzerland
ID NLM: 101509722

Informations de publication

Date de publication:
05 02 2020
Historique:
received: 20 12 2019
revised: 24 01 2020
accepted: 28 01 2020
entrez: 9 2 2020
pubmed: 9 2 2020
medline: 20 2 2021
Statut: epublish

Résumé

Infections with HIV-1 group M subtype B viruses account for the majority of the HIV epidemic in the Western world. Phylogeographic studies have placed the introduction of subtype B in the United States in New York around 1970, where it grew into a major source of spread. Currently, it is estimated that over one million people are living with HIV in the US and that most are infected with subtype B variants. Here, we aim to identify the drivers of HIV-1 subtype B dispersal in the United States by analyzing a collection of 23,588

Identifiants

pubmed: 32033422
pii: v12020182
doi: 10.3390/v12020182
pmc: PMC7077180
pii:
doi:

Types de publication

Journal Article Research Support, Non-U.S. Gov't

Langues

eng

Sous-ensembles de citation

IM

Subventions

Organisme : Wellcome Trust
ID : 206298/Z/17/Z
Pays : United Kingdom

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Auteurs

Samuel L Hong (SL)

Department of Microbiology, Immunology and Transplantation, Rega Institute for Medical Research, KU Leuven, 3000 Leuven, Belgium.

Simon Dellicour (S)

Department of Microbiology, Immunology and Transplantation, Rega Institute for Medical Research, KU Leuven, 3000 Leuven, Belgium.
Spatial Epidemiology Lab (SpELL), Université Libre de Bruxelles, 1050 Brussels, Belgium.

Bram Vrancken (B)

Department of Microbiology, Immunology and Transplantation, Rega Institute for Medical Research, KU Leuven, 3000 Leuven, Belgium.

Marc A Suchard (MA)

Department of Biomathematics, David Geffen School of Medicine at UCLA, University of California, Los Angeles, CA 90095, USA.
Department of Human Genetics, David Geffen School of Medicine at UCLA, University of California, Los Angeles, CA 90095, USA.
Department of Biostatistics, Fielding School of Public Health, University of California, Los Angeles, CA 90095, USA.

Michael T Pyne (MT)

ARUP Institute for Clinical and Experimental Pathology, Salt Lake City, UT 84108, USA.

David R Hillyard (DR)

Department of Pathology, University of Utah, Salt Lake City, UT 84112, USA.

Philippe Lemey (P)

Department of Microbiology, Immunology and Transplantation, Rega Institute for Medical Research, KU Leuven, 3000 Leuven, Belgium.

Guy Baele (G)

Department of Microbiology, Immunology and Transplantation, Rega Institute for Medical Research, KU Leuven, 3000 Leuven, Belgium.

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Classifications MeSH