Long-term results of polytetrafluoroethylene versus saphenous vein repair of degenerative carotid artery aneurysm.


Journal

Journal of vascular surgery
ISSN: 1097-6809
Titre abrégé: J Vasc Surg
Pays: United States
ID NLM: 8407742

Informations de publication

Date de publication:
10 2020
Historique:
received: 14 08 2019
accepted: 25 11 2019
pubmed: 10 2 2020
medline: 12 3 2021
entrez: 10 2 2020
Statut: ppublish

Résumé

To compare the results of polytetrafluoroethylene (PTFE) and great saphenous vein (GSV) bypass after resection of a degenerative aneurysm of the carotid artery. From January 1994 to November 2017, 37 patients (27 men) with a mean age of 58 years (range, 39-82 years) with a degenerative aneurysm of the carotid artery (median diameter, 28 mm; range, 19-42 mm), underwent resection of the aneurysm followed by a bypass with either a GSV (n = 10) or a PTFE prosthesis (n = 27). Although 31 patients were asymptomatic, 6 patients were symptomatic: transient ischemic attack (n = 4), minor stroke (n = 1), and compression of the hypoglossal nerve (n = 1). The preoperative workup included duplex ultrasound examination of the arteries to the head, and angiography or computed tomography angiography. All patients were operated under general anesthesia and six were intubated through the nose. Sixteen patients were monitored through transcutaneous oximetry. No shunt was used in this series. In 10 patients receiving a PTFE graft, the external carotid artery was implanted in the prosthesis. Mean follow-up was 16.9 ± 2 years (95% confidence interval, 14.5-19.3 years). Primary end points were the 30-day combined stroke/death rate, graft infection, late graft patency, and late stroke-free survival. Secondary end points were cranial nerve injury and length of postoperative hospital stay. Postoperative mortality was nil in both groups. One postoperative stroke was observed in the PTFE group, whereas none occurred in the GSV group (P = .84). No graft infection was observed in either group. At 10 years, survival in the GSV group was 80 ± 12%, and survival in the PTFE group was 76 ± 8% (log-rank [Mantel-Cox], P = .85). In the GSV group, graft patency at 7 and 10 years was 85 ± 13%. In the PTFE group B, graft patency was 100% (log-rank [Mantel-Cox], P = .12). No late stroke was observed. Two transient cranial nerve injuries were observed in the GSV group (20%) and two in the PTFE group (8%) (P = .97). Length of hospital stay was comparable in both groups (GSV group, 6 days; PTFE group, 5 days; P = .12). This study suggests that, after resection of a degenerative aneurysm of the carotid artery, bypass with a PTFE prosthesis gives comparable results to those obtained with the GSV. We recommend sparing the GSV and instead using a PTFE prosthesis in patients with a degenerative aneurysm of the carotid artery.

Identifiants

pubmed: 32035773
pii: S0741-5214(19)32903-9
doi: 10.1016/j.jvs.2019.11.054
pii:
doi:

Substances chimiques

Polytetrafluoroethylene 9002-84-0

Types de publication

Comparative Study Journal Article

Langues

eng

Sous-ensembles de citation

IM

Pagination

1413-1420

Informations de copyright

Copyright © 2019 Society for Vascular Surgery. Published by Elsevier Inc. All rights reserved.

Auteurs

Giulio Illuminati (G)

Department of Surgical Sciences, The University of Rome "La Sapienza", Rome, Italy. Electronic address: giulio.illuminati@uniroma1.it.

Giulia Pizzardi (G)

Department of Surgical Sciences, The University of Rome "La Sapienza", Rome, Italy.

Rocco Pasqua (R)

Department of Surgical Sciences, The University of Rome "La Sapienza", Rome, Italy.

Priscilla Nardi (P)

Department of Surgical Sciences, The University of Rome "La Sapienza", Rome, Italy.

Francesco G Calio' (FG)

Department of Surgical Sciences, The University of Rome "La Sapienza", Rome, Italy.

Jean-Baptiste Ricco (JB)

Department of Surgical Research, The University of Poitiers, Poitiers, France.

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Classifications MeSH